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Atomistry » Fluorine » PDB 5ddf-5dy7 » 5dos » |
Fluorine in PDB 5dos: Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122Enzymatic activity of Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122
All present enzymatic activity of Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122:
2.7.11.1; Protein crystallography data
The structure of Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122, PDB code: 5dos
was solved by
M.Janecek,
M.Rossmann,
P.Sharma,
A.Emery,
G.J.Mckenzie,
D.J.Huggins,
S.Stockwell,
J.A.Stokes,
E.G.Almeida,
B.Hardwick,
A.J.Narvaez,
M.Hyvonen,
D.R.Spring,
A.R.Venkitaraman,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5dos:
The structure of Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122
(pdb code 5dos). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122, PDB code: 5dos: Fluorine binding site 1 out of 1 in 5dosGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122
![]() Mono view ![]() Stereo pair view
Reference:
M.Janecek,
M.Rossmann,
P.Sharma,
A.Emery,
D.J.Huggins,
S.R.Stockwell,
J.E.Stokes,
Y.S.Tan,
E.G.Almeida,
B.Hardwick,
A.J.Narvaez,
M.Hyvonen,
D.R.Spring,
G.J.Mckenzie,
A.R.Venkitaraman.
Allosteric Modulation of Aurka Kinase Activity By A Small-Molecule Inhibitor of Its Protein-Protein Interaction with TPX2. Sci Rep V. 6 28528 2016.
Page generated: Tue Jul 15 03:05:33 2025
ISSN: ESSN 2045-2322 PubMed: 27339427 DOI: 10.1038/SREP28528 |
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