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Atomistry » Fluorine » PDB 5ihc-5j8m » 5j6l » |
Fluorine in PDB 5j6l: Crystal Structure of HSP90-Alpha N-Domain in Complex with N-Butyl-5- [4-(2-Fluoro-Phenyl)-5-Oxo-4,5-Dihydro-1H-[1,2,4]Triazol-3-Yl]-2,4- Dihydroxy-N-Methyl-BenzamideProtein crystallography data
The structure of Crystal Structure of HSP90-Alpha N-Domain in Complex with N-Butyl-5- [4-(2-Fluoro-Phenyl)-5-Oxo-4,5-Dihydro-1H-[1,2,4]Triazol-3-Yl]-2,4- Dihydroxy-N-Methyl-Benzamide, PDB code: 5j6l
was solved by
M.Amaral,
P.Matias,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of HSP90-Alpha N-Domain in Complex with N-Butyl-5- [4-(2-Fluoro-Phenyl)-5-Oxo-4,5-Dihydro-1H-[1,2,4]Triazol-3-Yl]-2,4- Dihydroxy-N-Methyl-Benzamide
(pdb code 5j6l). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of HSP90-Alpha N-Domain in Complex with N-Butyl-5- [4-(2-Fluoro-Phenyl)-5-Oxo-4,5-Dihydro-1H-[1,2,4]Triazol-3-Yl]-2,4- Dihydroxy-N-Methyl-Benzamide, PDB code: 5j6l: Fluorine binding site 1 out of 1 in 5j6lGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Crystal Structure of HSP90-Alpha N-Domain in Complex with N-Butyl-5- [4-(2-Fluoro-Phenyl)-5-Oxo-4,5-Dihydro-1H-[1,2,4]Triazol-3-Yl]-2,4- Dihydroxy-N-Methyl-Benzamide
![]() Mono view ![]() Stereo pair view
Reference:
M.Amaral,
D.B.Kokh,
J.Bomke,
A.Wegener,
H.P.Buchstaller,
H.M.Eggenweiler,
P.Matias,
C.Sirrenberg,
R.C.Wade,
M.Frech.
Protein Conformational Flexibility Modulates Kinetics and Thermodynamics of Drug Binding. Nat Commun V. 8 2276 2017.
Page generated: Tue Jul 15 04:18:00 2025
ISSN: ESSN 2041-1723 PubMed: 29273709 DOI: 10.1038/S41467-017-02258-W |
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