|
Atomistry » Fluorine » PDB 5jxy-5ko1 » 5kae | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5jxy-5ko1 » 5kae » |
Fluorine in PDB 5kae: Crystal Structure of Human PI3K-Gamma in Complex with Quinoline- Containing Inhibitor 5GEnzymatic activity of Crystal Structure of Human PI3K-Gamma in Complex with Quinoline- Containing Inhibitor 5G
All present enzymatic activity of Crystal Structure of Human PI3K-Gamma in Complex with Quinoline- Containing Inhibitor 5G:
2.7.1.153; 2.7.11.1; Protein crystallography data
The structure of Crystal Structure of Human PI3K-Gamma in Complex with Quinoline- Containing Inhibitor 5G, PDB code: 5kae
was solved by
D.A.Whittington,
J.Tang,
P.Yakowec,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human PI3K-Gamma in Complex with Quinoline- Containing Inhibitor 5G
(pdb code 5kae). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Human PI3K-Gamma in Complex with Quinoline- Containing Inhibitor 5G, PDB code: 5kae: Fluorine binding site 1 out of 1 in 5kaeGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Crystal Structure of Human PI3K-Gamma in Complex with Quinoline- Containing Inhibitor 5G
![]() Mono view ![]() Stereo pair view
Reference:
F.Gonzalez-Lopez De Turiso,
X.Hao,
Y.Shin,
M.Bui,
I.Campuzano,
M.Cardozo,
M.C.Dunn,
J.Duquette,
B.Fisher,
R.S.Foti,
K.Henne,
X.He,
Y.-L.Hu,
R.C.Kelly,
M.G.Johnson,
B.S.Lucas,
J.Mccarter,
L.R.Mcgee,
J.C.Medina,
D.Metz,
T.San Miguel,
D.Mohn,
T.Tran,
C.Vissinga,
S.Wannberg,
D.A.Whittington,
J.Whoriskey,
G.Yu,
L.Zalameda,
X.Zhang,
T.D.Cushing.
Discovery and in Vivo Evaluation of the Potent and Selective PI3K-Delta Inhibitors Am-0687 and Am-1430 To Be Published.
Page generated: Tue Jul 15 04:40:49 2025
|
Last articlesFe in 2YXOFe in 2YRS Fe in 2YXC Fe in 2YNM Fe in 2YVJ Fe in 2YP1 Fe in 2YU2 Fe in 2YU1 Fe in 2YQB Fe in 2YOO |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |