|
Atomistry » Fluorine » PDB 5le1-5lz5 » 5llc | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5le1-5lz5 » 5llc » |
Fluorine in PDB 5llc: Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3- (Methylamino)-2,5,6-Trifluoro-4-[(2-Phenylethyl) Sulfonyl]BenzenesulfonamideEnzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3- (Methylamino)-2,5,6-Trifluoro-4-[(2-Phenylethyl) Sulfonyl]Benzenesulfonamide
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3- (Methylamino)-2,5,6-Trifluoro-4-[(2-Phenylethyl) Sulfonyl]Benzenesulfonamide:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3- (Methylamino)-2,5,6-Trifluoro-4-[(2-Phenylethyl) Sulfonyl]Benzenesulfonamide, PDB code: 5llc
was solved by
E.Manakova,
A.Smirnov,
S.Grazulis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5llc:
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3- (Methylamino)-2,5,6-Trifluoro-4-[(2-Phenylethyl) Sulfonyl]Benzenesulfonamide also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3- (Methylamino)-2,5,6-Trifluoro-4-[(2-Phenylethyl) Sulfonyl]Benzenesulfonamide
(pdb code 5llc). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3- (Methylamino)-2,5,6-Trifluoro-4-[(2-Phenylethyl) Sulfonyl]Benzenesulfonamide, PDB code: 5llc: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 5llcGo back to![]() ![]()
Fluorine binding site 1 out
of 3 in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3- (Methylamino)-2,5,6-Trifluoro-4-[(2-Phenylethyl) Sulfonyl]Benzenesulfonamide
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 3 in 5llcGo back to![]() ![]()
Fluorine binding site 2 out
of 3 in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3- (Methylamino)-2,5,6-Trifluoro-4-[(2-Phenylethyl) Sulfonyl]Benzenesulfonamide
![]() Mono view ![]() Stereo pair view
Fluorine binding site 3 out of 3 in 5llcGo back to![]() ![]()
Fluorine binding site 3 out
of 3 in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3- (Methylamino)-2,5,6-Trifluoro-4-[(2-Phenylethyl) Sulfonyl]Benzenesulfonamide
![]() Mono view ![]() Stereo pair view
Reference:
A.Smirnov,
A.Zubriene,
E.Manakova,
S.Grazulis,
D.Matulis.
Crystal Structure Correlations with the Intrinsic Thermodynamics of Human Carbonic Anhydrase Inhibitor Binding. Peerj V. 6 E4412 2018.
Page generated: Tue Jul 15 05:00:38 2025
ISSN: ESSN 2167-8359 PubMed: 29503769 DOI: 10.7717/PEERJ.4412 |
Last articlesFe in 2YXOFe in 2YRS Fe in 2YXC Fe in 2YNM Fe in 2YVJ Fe in 2YP1 Fe in 2YU2 Fe in 2YU1 Fe in 2YQB Fe in 2YOO |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |