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Atomistry » Fluorine » PDB 5mt0-5nk2 » 5mt0 » |
Fluorine in PDB 5mt0: Complement Factor D in Complex with A Reversible Indole Carboxylic Acid Based InhibitorEnzymatic activity of Complement Factor D in Complex with A Reversible Indole Carboxylic Acid Based Inhibitor
All present enzymatic activity of Complement Factor D in Complex with A Reversible Indole Carboxylic Acid Based Inhibitor:
3.4.21.46; Protein crystallography data
The structure of Complement Factor D in Complex with A Reversible Indole Carboxylic Acid Based Inhibitor, PDB code: 5mt0
was solved by
A.Mac Sweeney,
N.Ostermann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Complement Factor D in Complex with A Reversible Indole Carboxylic Acid Based Inhibitor
(pdb code 5mt0). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Complement Factor D in Complex with A Reversible Indole Carboxylic Acid Based Inhibitor, PDB code: 5mt0: Fluorine binding site 1 out of 1 in 5mt0Go back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Complement Factor D in Complex with A Reversible Indole Carboxylic Acid Based Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
A.Vulpetti,
S.Randl,
S.Rudisser,
N.Ostermann,
P.Erbel,
A.Mac Sweeney,
T.Zoller,
B.Salem,
B.Gerhartz,
F.Cumin,
U.Hommel,
C.Dalvit,
E.Lorthiois,
J.Maibaum.
Structure-Based Library Design and Fragment Screening For the Identification of Reversible Complement Factor D Protease Inhibitors. J. Med. Chem. V. 60 1946 2017.
Page generated: Tue Jul 15 05:22:28 2025
ISSN: ISSN 1520-4804 PubMed: 28157311 DOI: 10.1021/ACS.JMEDCHEM.6B01684 |
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