Atomistry » Fluorine » PDB 5olx-5p93 » 5olx
Atomistry »
  Fluorine »
    PDB 5olx-5p93 »
      5olx »

Fluorine in PDB 5olx: 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form

Enzymatic activity of 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form

All present enzymatic activity of 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form:
5.4.2.6;

Protein crystallography data

The structure of 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form, PDB code: 5olx was solved by M.W.Bowler, J.Von Velsen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 1.38
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 37.530, 54.164, 104.225, 90.00, 90.00, 90.00
R / Rfree (%) 15.4 / 20.9

Other elements in 5olx:

The structure of 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form also contains other interesting chemical elements:

Magnesium (Mg) 3 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form (pdb code 5olx). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 5 binding sites of Fluorine where determined in the 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form, PDB code: 5olx:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5;

Fluorine binding site 1 out of 5 in 5olx

Go back to Fluorine Binding Sites List in 5olx
Fluorine binding site 1 out of 5 in the 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F24

b:11.3
occ:1.00
F A:FTR24 0.0 11.3 1.0
CZ3 A:FTR24 1.3 8.5 1.0
CH2 A:FTR24 2.3 8.4 1.0
CE3 A:FTR24 2.4 7.4 1.0
CD1 A:LEU27 3.5 8.5 1.0
CD1 A:LEU53 3.5 8.3 1.0
CB A:LEU53 3.5 8.1 1.0
CZ2 A:FTR24 3.6 7.3 1.0
CG A:LEU27 3.6 9.2 1.0
CD2 A:FTR24 3.6 6.6 1.0
CG A:LEU53 3.9 7.5 1.0
CA A:LEU53 4.0 8.5 1.0
CB A:LYS76 4.0 6.4 1.0
CE2 A:FTR24 4.1 6.2 1.0
CD2 A:LEU53 4.2 9.1 1.0
O A:LEU72 4.2 8.3 1.0
CG A:LYS76 4.4 7.9 1.0
CB A:LEU27 4.4 7.8 1.0
CA A:ALA73 4.5 8.8 1.0
C A:LEU72 4.5 6.7 1.0
N A:LEU53 4.5 7.9 1.0
CD1 A:ILE56 4.7 10.2 1.0
N A:ALA73 4.7 7.9 1.0
CD2 A:LEU27 4.7 10.4 1.0
CD A:LYS76 4.9 7.5 1.0
CG A:FTR24 4.9 6.6 1.0

Fluorine binding site 2 out of 5 in 5olx

Go back to Fluorine Binding Sites List in 5olx
Fluorine binding site 2 out of 5 in the 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F216

b:18.1
occ:1.00
F A:FTR216 0.0 18.1 1.0
CZ3 A:FTR216 1.3 13.1 1.0
CE3 A:FTR216 2.3 10.6 1.0
CH2 A:FTR216 2.3 13.4 1.0
O A:SER165 3.0 9.9 1.0
CB A:LEU184 3.3 10.1 1.0
C A:SER165 3.5 8.2 1.0
CD2 A:FTR216 3.5 10.3 1.0
CZ2 A:FTR216 3.6 12.2 1.0
CG1 A:ILE166 3.6 7.8 1.0
N A:SER165 4.0 8.2 1.0
CD2 A:LEU184 4.0 17.6 1.0
N A:ILE166 4.0 7.2 1.0
CE2 A:FTR216 4.0 12.2 1.0
N A:LEU184 4.1 8.6 1.0
CB A:PHE2 4.2 8.4 1.0
CA A:SER165 4.3 8.3 1.0
CG A:LEU184 4.3 12.8 1.0
O A:SER163 4.3 16.7 1.0
CA A:LEU184 4.3 8.5 1.0
CA A:ILE166 4.3 7.5 1.0
C A:GLU164 4.4 8.3 1.0
CD1 A:ILE166 4.6 8.9 1.0
CB A:ILE166 4.6 7.3 1.0
O A:GLU164 4.8 11.4 1.0
CA A:GLU164 4.8 11.2 1.0
CG A:FTR216 4.9 10.9 1.0
C A:SER163 4.9 13.4 1.0

Fluorine binding site 3 out of 5 in 5olx

Go back to Fluorine Binding Sites List in 5olx
Fluorine binding site 3 out of 5 in the 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F305

b:7.4
occ:1.00
MG A:MGF304 1.9 8.0 1.0
MG A:MG301 2.0 7.1 1.0
O2 A:BG6302 2.6 8.0 1.0
O A:HOH485 2.8 6.6 1.0
O1 A:BG6302 2.8 7.4 1.0
O A:HOH428 2.9 5.8 1.0
O A:ASP10 2.9 5.8 1.0
OD2 A:ASP8 3.0 6.8 1.0
OD1 A:ASP8 3.0 8.5 1.0
F1 A:MGF306 3.0 7.4 1.0
CB A:ASP10 3.2 5.7 1.0
CG A:ASP8 3.3 6.1 1.0
F1 A:MGF307 3.3 11.1 1.0
C2 A:BG6302 3.4 7.0 1.0
C1 A:BG6302 3.5 7.8 1.0
N A:ASP10 3.5 5.9 1.0
CA A:ASP10 3.6 5.4 1.0
C A:ASP10 3.6 5.2 1.0
OD2 A:ASP10 3.8 7.0 1.0
CG A:ASP10 3.9 5.9 1.0
OD1 A:ASP170 4.0 6.0 1.0
O A:HOH541 4.3 8.2 1.0
N A:GLY46 4.4 7.1 1.0
CA A:GLY46 4.5 7.7 1.0
C A:LEU9 4.6 6.0 1.0
N A:LEU9 4.7 5.4 1.0
C3 A:BG6302 4.8 7.8 1.0
O5 A:BG6302 4.8 7.3 1.0
CB A:ASP8 4.8 6.1 1.0
CG A:ASP170 4.9 5.9 1.0
N A:GLY11 4.9 6.3 1.0
OD2 A:ASP170 4.9 6.7 1.0

Fluorine binding site 4 out of 5 in 5olx

Go back to Fluorine Binding Sites List in 5olx
Fluorine binding site 4 out of 5 in the 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F306

b:7.4
occ:1.00
MG A:MGF304 1.9 8.0 1.0
OG A:SER114 2.6 7.5 1.0
O1 A:BG6302 2.7 7.4 1.0
N A:ASP10 2.7 5.9 1.0
OD1 A:ASP8 2.8 8.5 1.0
N A:LEU9 2.9 5.4 1.0
F1 A:MGF305 3.0 7.4 1.0
CB A:LEU9 3.2 5.9 1.0
OD2 A:ASP10 3.3 7.0 1.0
CB A:SER114 3.3 8.4 1.0
CA A:LEU9 3.3 6.5 1.0
F1 A:MGF307 3.4 11.1 1.0
C A:LEU9 3.5 6.0 1.0
CG A:ASP10 3.6 5.9 1.0
CG A:ASP8 3.6 6.1 1.0
CA A:SER114 3.7 8.2 1.0
CB A:ASP10 3.8 5.7 1.0
CA A:ASP10 3.8 5.4 1.0
C A:ASP8 4.0 6.0 1.0
OD2 A:ASP8 4.1 6.8 1.0
C1 A:BG6302 4.1 7.8 1.0
OD1 A:ASP10 4.2 8.2 1.0
N A:ALA115 4.4 9.0 1.0
CA A:ASP8 4.4 5.4 1.0
MG A:MG301 4.5 7.1 1.0
C A:SER114 4.5 8.5 1.0
O A:ASP10 4.5 5.8 1.0
CG A:LEU9 4.6 8.1 1.0
CB A:ASP8 4.6 6.1 1.0
CB A:SER116 4.7 8.0 1.0
O A:LEU9 4.7 5.8 1.0
C A:ASP10 4.7 5.2 1.0
N A:SER116 4.8 8.3 1.0
O5 A:BG6302 4.8 7.3 1.0
C2 A:BG6302 4.8 7.0 1.0
N A:SER114 4.9 8.7 1.0
O2 A:BG6302 4.9 8.0 1.0
CD2 A:LEU9 4.9 9.3 1.0

Fluorine binding site 5 out of 5 in 5olx

Go back to Fluorine Binding Sites List in 5olx
Fluorine binding site 5 out of 5 in the 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of 5-Fluorotryptophan Labeled Beta-Phosphoglucomutase in A Closed Conformation, Orthorhomic Crystal Form within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F307

b:11.1
occ:1.00
MG A:MGF304 1.8 8.0 1.0
NZ A:LYS145 2.5 8.5 1.0
O1 A:BG6302 2.8 7.4 1.0
OD1 A:ASP8 2.8 8.5 1.0
N A:ALA115 2.9 9.0 1.0
C1 A:BG6302 3.3 7.8 1.0
F1 A:MGF305 3.3 7.4 1.0
F1 A:MGF306 3.4 7.4 1.0
CB A:ALA115 3.4 12.2 1.0
CE A:LYS145 3.4 9.1 1.0
CA A:ALA115 3.7 10.0 1.0
CA A:SER114 3.7 8.2 1.0
C A:SER114 3.7 8.5 1.0
CD A:LYS145 3.8 8.3 1.0
O A:HOH485 3.9 6.6 1.0
CG A:ASP8 3.9 6.1 1.0
CA A:GLY46 4.0 7.7 1.0
O2 A:BG6302 4.1 8.0 1.0
OG A:SER114 4.2 7.5 1.0
O5 A:BG6302 4.2 7.3 1.0
OE2 A:GLU169 4.3 10.1 1.0
C2 A:BG6302 4.3 7.0 1.0
O A:ALA113 4.3 8.0 1.0
OD2 A:ASP8 4.5 6.8 1.0
CB A:SER114 4.5 8.4 1.0
O A:GLY46 4.5 9.7 1.0
N A:SER116 4.6 8.3 1.0
C A:GLY46 4.6 8.9 1.0
C A:ALA115 4.6 8.8 1.0
MG A:MG301 4.7 7.1 1.0
N A:SER114 4.8 8.7 1.0
O A:SER114 4.9 11.2 1.0
N A:GLY46 4.9 7.1 1.0
CB A:ASP8 5.0 6.1 1.0
C A:ALA113 5.0 7.5 1.0

Reference:

A.Ampaw, M.Carroll, J.Von Velsen, D.Bhattasali, A.Cohen, M.W.Bowler, D.L.Jakeman. Observing Enzyme Ternary Transition State Analogue Complexes BY19F uc(Nmr) Spectroscopy. Chem Sci V. 8 8427 2017.
ISSN: ISSN 2041-6520
PubMed: 29619190
DOI: 10.1039/C7SC04204C
Page generated: Tue Jul 15 05:51:41 2025

Last articles

Mg in 6CA4
Mg in 6C90
Mg in 6CA0
Mg in 6C9Y
Mg in 6C8Z
Mg in 6C8P
Mg in 6C8N
Mg in 6C8O
Mg in 6C8D
Mg in 6C8L
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy