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Atomistry » Fluorine » PDB 5p93-5pzk » 5p9g | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5p93-5pzk » 5p9g » |
Fluorine in PDB 5p9g: Structure of Btk with RN486Enzymatic activity of Structure of Btk with RN486
All present enzymatic activity of Structure of Btk with RN486:
2.7.10.2; Protein crystallography data
The structure of Structure of Btk with RN486, PDB code: 5p9g
was solved by
A.S.Gardberg,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of Btk with RN486
(pdb code 5p9g). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structure of Btk with RN486, PDB code: 5p9g: Fluorine binding site 1 out of 1 in 5p9gGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Structure of Btk with RN486
![]() Mono view ![]() Stereo pair view
Reference:
A.T.Bender,
A.Gardberg,
A.Pereira,
T.Johnson,
Y.Wu,
R.Grenningloh,
J.Head,
F.Morandi,
P.Haselmayer,
L.Liu-Bujalski.
Ability of Bruton'S Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency For Inhibition of Fc Receptor But Not B-Cell Receptor Signaling. Mol. Pharmacol. V. 91 208 2017.
Page generated: Thu Aug 1 12:44:43 2024
ISSN: ESSN 1521-0111 PubMed: 28062735 DOI: 10.1124/MOL.116.107037 |
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