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Atomistry » Fluorine » PDB 5xdk-5y6d » 5xst » |
Fluorine in PDB 5xst: Novel Orally Efficacious Inhibitors Complexed with PARP1Enzymatic activity of Novel Orally Efficacious Inhibitors Complexed with PARP1
All present enzymatic activity of Novel Orally Efficacious Inhibitors Complexed with PARP1:
2.4.2.30; Protein crystallography data
The structure of Novel Orally Efficacious Inhibitors Complexed with PARP1, PDB code: 5xst
was solved by
Q.Liu,
Y.Xu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Novel Orally Efficacious Inhibitors Complexed with PARP1
(pdb code 5xst). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Novel Orally Efficacious Inhibitors Complexed with PARP1, PDB code: 5xst: Fluorine binding site 1 out of 1 in 5xstGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Novel Orally Efficacious Inhibitors Complexed with PARP1
![]() Mono view ![]() Stereo pair view
Reference:
X.Chen,
X.Huan,
Q.Liu,
Y.Wang,
Q.He,
C.Tan,
Y.Chen,
J.Ding,
Y.Xu,
Z.Miao,
C.Yang.
Design and Synthesis of 2-(4,5,6,7-Tetrahydrothienopyridin-2-Yl)-Benzoimidazole Carboxamides As Novel Orally Efficacious Poly(Adp-Ribose)Polymerase (Parp) Inhibitors Eur J Med Chem V. 145 389 2018.
Page generated: Tue Jul 15 09:19:20 2025
ISSN: ISSN 1768-3254 PubMed: 29335205 DOI: 10.1016/J.EJMECH.2018.01.018 |
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