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Atomistry » Fluorine » PDB 5zg2-6aol » 5zma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5zg2-6aol » 5zma » |
Fluorine in PDB 5zma: Structural Basis For An Allosteric EYA2 Phosphatase InhibitorEnzymatic activity of Structural Basis For An Allosteric EYA2 Phosphatase Inhibitor
All present enzymatic activity of Structural Basis For An Allosteric EYA2 Phosphatase Inhibitor:
3.1.3.48; Protein crystallography data
The structure of Structural Basis For An Allosteric EYA2 Phosphatase Inhibitor, PDB code: 5zma
was solved by
J.Anantharajan,
A.E.Jansson,
C.Kang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structural Basis For An Allosteric EYA2 Phosphatase Inhibitor
(pdb code 5zma). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Structural Basis For An Allosteric EYA2 Phosphatase Inhibitor, PDB code: 5zma: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 5zmaGo back to![]() ![]()
Fluorine binding site 1 out
of 3 in the Structural Basis For An Allosteric EYA2 Phosphatase Inhibitor
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 3 in 5zmaGo back to![]() ![]()
Fluorine binding site 2 out
of 3 in the Structural Basis For An Allosteric EYA2 Phosphatase Inhibitor
![]() Mono view ![]() Stereo pair view
Fluorine binding site 3 out of 3 in 5zmaGo back to![]() ![]()
Fluorine binding site 3 out
of 3 in the Structural Basis For An Allosteric EYA2 Phosphatase Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
J.Anantharajan,
H.Zhou,
L.Zhang,
T.Hotz,
M.Y.Vincent,
M.A.Blevins,
A.E.Jansson,
J.W.L.Kuan,
E.Y.Ng,
Y.K.Yeo,
N.Baburajendran,
G.Lin,
A.W.Hung,
J.Joy,
S.Patnaik,
J.Marugan,
P.Rudra,
D.Ghosh,
J.Hill,
T.H.Keller,
R.Zhao,
H.L.Ford,
C.Kang.
Structural and Functional Analyses of An Allosteric EYA2 Phosphatase Inhibitor That Has on-Target Effects in Human Lung Cancer Cells. Mol.Cancer Ther. V. 18 1484 2019.
Page generated: Tue Jul 15 09:37:55 2025
ISSN: ESSN 1538-8514 PubMed: 31285279 DOI: 10.1158/1535-7163.MCT-18-1239 |
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