Fluorine in PDB 6bq1: Human PI4KIIIA Lipid Kinase Complex

All present enzymatic activity of Human PI4KIIIA Lipid Kinase Complex:
2.7.1.67;

The binding sites of Fluorine atom in the Human PI4KIIIA Lipid Kinase Complex (pdb code 6bq1). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Human PI4KIIIA Lipid Kinase Complex, PDB code: 6bq1:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the Human PI4KIIIA Lipid Kinase Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human PI4KIIIA Lipid Kinase Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:F2201 b:77.1 occ:1.00 F01 A:E4S2201 0.0 77.1 1.0 C29 A:E4S2201 1.4 77.1 1.0 C28 A:E4S2201 2.3 77.1 1.0 C24 A:E4S2201 2.5 77.1 1.0 H27 A:E4S2201 2.5 77.1 1.0 OD1 A:ASN1962 2.6 1.0 1.0 O04 A:E4S2201 2.7 77.1 1.0 N06 A:E4S2201 2.9 77.1 1.0 S01 A:E4S2201 3.3 77.1 1.0 H23 A:E4S2201 3.4 77.1 1.0 C25 A:E4S2201 3.7 77.1 1.0 CG A:ASN1962 3.7 1.0 1.0 C27 A:E4S2201 3.7 77.1 1.0 O03 A:E4S2201 3.9 77.1 1.0 ND2 A:ASN1962 4.1 1.0 1.0 C26 A:E4S2201 4.2 77.1 1.0 H24 A:E4S2201 4.4 77.1 1.0 H26 A:E4S2201 4.5 77.1 1.0 O A:SER1797 4.9 0.2 1.0 C03 A:E4S2201 4.9 77.1 1.0 CB A:ASN1962 5.0 1.0 1.0

Fluorine binding site 2 out of 2 in the Human PI4KIIIA Lipid Kinase Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Human PI4KIIIA Lipid Kinase Complex within 5.0Å range: probe atom residue distance (Å) B Occ E:F2201 b:66.5 occ:1.00 F01 E:E4S2201 0.0 66.5 1.0 C29 E:E4S2201 1.4 66.5 1.0 C28 E:E4S2201 2.3 66.5 1.0 C24 E:E4S2201 2.5 66.5 1.0 H27 E:E4S2201 2.5 66.5 1.0 O04 E:E4S2201 2.6 66.5 1.0 OD1 E:ASN1962 2.9 0.9 1.0 N06 E:E4S2201 2.9 66.5 1.0 S01 E:E4S2201 3.3 66.5 1.0 H23 E:E4S2201 3.4 66.5 1.0 C25 E:E4S2201 3.7 66.5 1.0 C27 E:E4S2201 3.7 66.5 1.0 CG E:ASN1962 4.0 0.9 1.0 O03 E:E4S2201 4.2 66.5 1.0 C26 E:E4S2201 4.2 66.5 1.0 H24 E:E4S2201 4.4 66.5 1.0 H26 E:E4S2201 4.5 66.5 1.0 ND2 E:ASN1962 4.6 0.9 1.0 C03 E:E4S2201 4.6 66.5 1.0 O E:SER1797 4.9 0.6 1.0

J.A.Lees, Y.Zhang, M.S.Oh, C.M.Schauder, X.Yu, J.M.Baskin, K.Dobbs, L.D.Notarangelo, P.De Camilli, T.Walz, K.M.Reinisch. Architecture of the Human PI4KIII Alpha Lipid Kinase Complex. Proc. Natl. Acad. Sci. V. 114 13720 2017U.S.A..
ISSN: ESSN 1091-6490
PubMed: 29229838
DOI: 10.1073/PNAS.1718471115