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Atomistry » Fluorine » PDB 6d4w-6dkw » 6d5h | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 6d4w-6dkw » 6d5h » |
Fluorine in PDB 6d5h: Ras:Sos:Ras in Complex with A Small Molecule ActivatorProtein crystallography data
The structure of Ras:Sos:Ras in Complex with A Small Molecule Activator, PDB code: 6d5h
was solved by
J.Phan,
T.Hodges,
S.W.Fesik,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6d5h:
The structure of Ras:Sos:Ras in Complex with A Small Molecule Activator also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Ras:Sos:Ras in Complex with A Small Molecule Activator
(pdb code 6d5h). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Ras:Sos:Ras in Complex with A Small Molecule Activator, PDB code: 6d5h: Fluorine binding site 1 out of 1 in 6d5hGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Ras:Sos:Ras in Complex with A Small Molecule Activator
![]() Mono view ![]() Stereo pair view
Reference:
T.R.Hodges,
J.R.Abbott,
A.J.Little,
D.Sarkar,
J.M.Salovich,
J.E.Howes,
D.T.Akan,
J.Sai,
A.L.Arnold,
C.Browning,
M.C.Burns,
T.Sobolik,
Q.Sun,
Y.Beesetty,
J.A.Coker,
D.Scharn,
H.Stadtmueller,
O.W.Rossanese,
J.Phan,
A.G.Waterson,
D.B.Mcconnell,
S.W.Fesik.
Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on Ras. J. Med. Chem. V. 61 8875 2018.
Page generated: Tue Jul 15 10:37:08 2025
ISSN: ISSN 1520-4804 PubMed: 30205005 DOI: 10.1021/ACS.JMEDCHEM.8B01108 |
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