Atomistry » Fluorine » PDB 6ffb-6g0l » 6fn1
Atomistry »
  Fluorine »
    PDB 6ffb-6g0l »
      6fn1 »

Fluorine in PDB 6fn1: Zosuquidar and UIC2 Fab Complex of Human-Mouse Chimeric ABCB1 (ABCB1HM)

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Zosuquidar and UIC2 Fab Complex of Human-Mouse Chimeric ABCB1 (ABCB1HM) (pdb code 6fn1). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Zosuquidar and UIC2 Fab Complex of Human-Mouse Chimeric ABCB1 (ABCB1HM), PDB code: 6fn1:
Jump to Fluorine binding site number: 1; 2; 3; 4;

Fluorine binding site 1 out of 4 in 6fn1

Go back to Fluorine Binding Sites List in 6fn1
Fluorine binding site 1 out of 4 in the Zosuquidar and UIC2 Fab Complex of Human-Mouse Chimeric ABCB1 (ABCB1HM)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Zosuquidar and UIC2 Fab Complex of Human-Mouse Chimeric ABCB1 (ABCB1HM) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1304

b:65.1
occ:1.00
F01 A:ZQU1304 0.0 65.1 1.0
C03 A:ZQU1304 1.4 65.1 1.0
F02 A:ZQU1304 2.2 65.1 1.0
C01 A:ZQU1304 2.5 65.1 1.0
C02 A:ZQU1304 2.5 65.1 1.0
C04 A:ZQU1304 2.9 65.1 1.0
C05 A:ZQU1304 3.0 65.1 1.0
C09 A:ZQU1304 3.1 65.1 1.0
CD2 A:LEU338 3.1 0.9 1.0
CG2 A:ILE339 3.4 0.2 1.0
C10 A:ZQU1304 3.4 65.1 1.0
CA A:ILE339 3.8 0.2 1.0
C07 A:ZQU1304 3.8 65.1 1.0
N A:ILE339 3.8 0.2 1.0
O A:LEU338 3.8 0.9 1.0
C08 A:ZQU1304 3.9 65.1 1.0
C A:LEU338 3.9 0.9 1.0
CB A:ILE339 4.1 0.2 1.0
C17 A:ZQU1304 4.2 65.1 1.0
CG A:LEU338 4.2 0.9 1.0
CB A:PHE342 4.4 0.0 1.0
C18 A:ZQU1304 4.5 65.1 1.0
C06 A:ZQU1304 4.5 65.1 1.0
CG A:PHE342 4.6 0.0 1.0
CB A:LEU338 4.6 0.9 1.0
F02 A:ZQU1305 4.7 64.3 1.0
C13 A:ZQU1304 4.7 65.1 1.0
CD2 A:PHE342 4.8 0.0 1.0
C14 A:ZQU1304 4.9 65.1 1.0
C19 A:ZQU1304 4.9 65.1 1.0
CA A:LEU338 4.9 0.9 1.0

Fluorine binding site 2 out of 4 in 6fn1

Go back to Fluorine Binding Sites List in 6fn1
Fluorine binding site 2 out of 4 in the Zosuquidar and UIC2 Fab Complex of Human-Mouse Chimeric ABCB1 (ABCB1HM)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Zosuquidar and UIC2 Fab Complex of Human-Mouse Chimeric ABCB1 (ABCB1HM) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1304

b:65.1
occ:1.00
F02 A:ZQU1304 0.0 65.1 1.0
C03 A:ZQU1304 1.4 65.1 1.0
F01 A:ZQU1304 2.2 65.1 1.0
C01 A:ZQU1304 2.5 65.1 1.0
C02 A:ZQU1304 2.5 65.1 1.0
CD2 A:LEU338 3.1 0.9 1.0
F02 A:ZQU1305 3.4 64.3 1.0
C04 A:ZQU1304 3.7 65.1 1.0
C05 A:ZQU1304 3.8 65.1 1.0
CG A:PHE342 3.8 0.0 1.0
CD2 A:PHE342 3.9 0.0 1.0
C09 A:ZQU1304 4.0 65.1 1.0
CD1 A:PHE342 4.1 0.0 1.0
CG2 A:ILE305 4.1 0.4 1.0
CE2 A:PHE342 4.2 0.0 1.0
CG A:LEU338 4.2 0.9 1.0
C10 A:ZQU1304 4.3 65.1 1.0
CE1 A:PHE342 4.3 0.0 1.0
CZ A:PHE342 4.3 0.0 1.0
CB A:PHE342 4.4 0.0 1.0
CB A:ILE305 4.6 0.4 1.0
O A:LEU338 4.6 0.9 1.0
C03 A:ZQU1305 4.7 64.3 1.0
C07 A:ZQU1304 4.9 65.1 1.0
CD1 A:ILE305 4.9 0.4 1.0
C08 A:ZQU1304 5.0 65.1 1.0

Fluorine binding site 3 out of 4 in 6fn1

Go back to Fluorine Binding Sites List in 6fn1
Fluorine binding site 3 out of 4 in the Zosuquidar and UIC2 Fab Complex of Human-Mouse Chimeric ABCB1 (ABCB1HM)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Zosuquidar and UIC2 Fab Complex of Human-Mouse Chimeric ABCB1 (ABCB1HM) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1305

b:64.3
occ:1.00
F01 A:ZQU1305 0.0 64.3 1.0
C03 A:ZQU1305 1.4 64.3 1.0
F02 A:ZQU1305 2.2 64.3 1.0
C02 A:ZQU1305 2.5 64.3 1.0
C01 A:ZQU1305 2.5 64.3 1.0
C04 A:ZQU1305 2.9 64.3 1.0
C05 A:ZQU1305 2.9 64.3 1.0
C09 A:ZQU1305 3.2 64.3 1.0
C10 A:ZQU1305 3.3 64.3 1.0
CD1 A:TRP231 3.3 0.2 1.0
NE1 A:TRP231 3.3 0.2 1.0
CE1 A:PHE342 3.8 0.0 1.0
CD1 A:PHE342 3.8 0.0 1.0
C07 A:ZQU1305 3.9 64.3 1.0
C08 A:ZQU1305 3.9 64.3 1.0
C17 A:ZQU1305 4.2 64.3 1.0
C18 A:ZQU1305 4.3 64.3 1.0
C06 A:ZQU1305 4.5 64.3 1.0
CG A:TRP231 4.6 0.2 1.0
CE2 A:TRP231 4.6 0.2 1.0
C13 A:ZQU1305 4.8 64.3 1.0
C14 A:ZQU1305 4.8 64.3 1.0
C19 A:ZQU1305 4.9 64.3 1.0
C20 A:ZQU1305 5.0 64.3 1.0

Fluorine binding site 4 out of 4 in 6fn1

Go back to Fluorine Binding Sites List in 6fn1
Fluorine binding site 4 out of 4 in the Zosuquidar and UIC2 Fab Complex of Human-Mouse Chimeric ABCB1 (ABCB1HM)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Zosuquidar and UIC2 Fab Complex of Human-Mouse Chimeric ABCB1 (ABCB1HM) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1305

b:64.3
occ:1.00
F02 A:ZQU1305 0.0 64.3 1.0
C03 A:ZQU1305 1.4 64.3 1.0
F01 A:ZQU1305 2.2 64.3 1.0
C01 A:ZQU1305 2.4 64.3 1.0
C02 A:ZQU1305 2.6 64.3 1.0
CD1 A:PHE342 3.0 0.0 1.0
C01 A:ZQU1304 3.2 65.1 1.0
CE1 A:PHE342 3.2 0.0 1.0
F02 A:ZQU1304 3.4 65.1 1.0
C04 A:ZQU1305 3.6 64.3 1.0
C03 A:ZQU1304 3.7 65.1 1.0
CG A:PHE342 3.8 0.0 1.0
C05 A:ZQU1305 3.8 64.3 1.0
C09 A:ZQU1304 3.8 65.1 1.0
C04 A:ZQU1304 3.9 65.1 1.0
C09 A:ZQU1305 3.9 64.3 1.0
CZ A:PHE342 4.2 0.0 1.0
C10 A:ZQU1305 4.3 64.3 1.0
C02 A:ZQU1304 4.4 65.1 1.0
CB A:PHE342 4.4 0.0 1.0
F01 A:ZQU1304 4.7 65.1 1.0
CD2 A:PHE342 4.7 0.0 1.0
CG2 A:ILE305 4.7 0.4 1.0
C07 A:ZQU1305 4.8 64.3 1.0
CE2 A:PHE342 4.9 0.0 1.0
C08 A:ZQU1305 5.0 64.3 1.0
C17 A:ZQU1304 5.0 65.1 1.0

Reference:

A.Alam, R.Kung, J.Kowal, R.A.Mcleod, N.Tremp, E.V.Broude, I.B.Roninson, H.Stahlberg, K.P.Locher. Structure of A Zosuquidar and UIC2-Bound Human-Mouse Chimeric ABCB1. Proc. Natl. Acad. Sci. V. 115 E1973 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 29440498
DOI: 10.1073/PNAS.1717044115
Page generated: Tue Jul 15 11:33:35 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy