Atomistry » Fluorine » PDB 6ffb-6g0l » 6fvf
Atomistry »
  Fluorine »
    PDB 6ffb-6g0l »
      6fvf »

Fluorine in PDB 6fvf: The Structure of CK2ALPHA with CCH503 Bound

Enzymatic activity of The Structure of CK2ALPHA with CCH503 Bound

All present enzymatic activity of The Structure of CK2ALPHA with CCH503 Bound:
2.7.11.1;

Protein crystallography data

The structure of The Structure of CK2ALPHA with CCH503 Bound, PDB code: 6fvf was solved by P.Brear, R.Prudent, B.Laudet, O.Filhol, C.Cochet, C.Sautel, V.Moucadel, B.Bestgen, M.Engel, M.Ettaoussi, T.Lomberget, M.Le Borgne, I.Kufareva, R.Abagyan, M.Hyvonen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 58.53 / 1.47
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 58.987, 45.250, 62.751, 90.00, 111.15, 90.00
R / Rfree (%) 20 / 22.2

Fluorine Binding Sites:

The binding sites of Fluorine atom in the The Structure of CK2ALPHA with CCH503 Bound (pdb code 6fvf). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the The Structure of CK2ALPHA with CCH503 Bound, PDB code: 6fvf:

Fluorine binding site 1 out of 1 in 6fvf

Go back to Fluorine Binding Sites List in 6fvf
Fluorine binding site 1 out of 1 in the The Structure of CK2ALPHA with CCH503 Bound


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of The Structure of CK2ALPHA with CCH503 Bound within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F401

b:47.9
occ:1.00
F A:503401 0.0 47.9 1.0
C5 A:503401 1.4 49.7 1.0
C6 A:503401 2.3 50.2 1.0
C4 A:503401 2.3 50.8 1.0
CB A:ALA110 3.1 33.7 1.0
OD1 A:ASP103 3.1 59.4 1.0
CG1 A:ILE69 3.1 34.4 1.0
CD1 A:ILE69 3.2 40.3 1.0
CB A:ASP103 3.6 48.7 1.0
C3 A:503401 3.6 53.7 1.0
C7 A:503401 3.6 52.7 1.0
CA A:ASP103 3.7 46.6 1.0
CG A:ASP103 3.8 59.6 1.0
CG1 A:VAL67 4.0 31.1 1.0
C2 A:503401 4.1 54.5 1.0
CG2 A:ILE69 4.2 33.9 1.0
CB A:ILE69 4.2 33.9 1.0
N A:ASP103 4.3 46.0 1.0
CA A:ALA110 4.5 32.9 1.0
CD A:PRO104 4.8 54.3 1.0
CG2 A:VAL101 4.9 37.8 1.0
C8 A:503401 5.0 54.9 1.0
C A:LYS102 5.0 47.9 1.0

Reference:

R.Prudent, B.Laudet, O.Filhol, C.Cochet, C.Sautel, V.Moucadel, B.Bestgen, M.Engel, M.Ettaoussi, T.Lomberget, M.Le Borgne, I.Kufareva, R.Abagyan, P.Brear, M.Hyvonen. Structure-Based Discovery of Small Molecules Targeting the Flexible CK2 Subunit Interface To Be Published.
Page generated: Tue Jul 15 11:41:20 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy