Fluorine in PDB 6g2f: X-Ray Structure of NSD3-PWWP1 in Complex with Compound 16

All present enzymatic activity of X-Ray Structure of NSD3-PWWP1 in Complex with Compound 16:
2.1.1.43;

The structure of X-Ray Structure of NSD3-PWWP1 in Complex with Compound 16, PDB code: 6g2f was solved by J.Boettcher, B.J.Muellauer, A.Weiss-Puxbaum, A.Zoephel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.39 / 1.74
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	43.927, 48.127, 63.662, 90.00, 90.00, 90.00
R / Rfree (%)	19.7 / 21.1

The binding sites of Fluorine atom in the X-Ray Structure of NSD3-PWWP1 in Complex with Compound 16 (pdb code 6g2f). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the X-Ray Structure of NSD3-PWWP1 in Complex with Compound 16, PDB code: 6g2f:

Fluorine binding site 1 out of 1 in the X-Ray Structure of NSD3-PWWP1 in Complex with Compound 16


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of X-Ray Structure of NSD3-PWWP1 in Complex with Compound 16 within 5.0Å range: probe atom residue distance (Å) B Occ A:F401 b:38.1 occ:1.00 F24 A:EHW401 0.0 38.1 1.0 C2 A:EHW401 1.4 37.9 1.0 C3 A:EHW401 2.3 33.5 1.0 C1 A:EHW401 2.3 36.6 1.0 CB A:GLN367 3.3 41.3 1.0 C4 A:EHW401 3.6 34.3 1.0 CG A:GLN367 3.6 57.5 1.0 C6 A:EHW401 3.6 32.7 1.0 CH2 A:TRP284 3.7 32.5 1.0 NE2 A:GLN367 3.8 75.5 1.0 CD A:GLN367 4.0 79.4 1.0 C5 A:EHW401 4.1 29.3 1.0 CA A:GLU364 4.1 44.4 1.0 CG A:GLU364 4.2 48.9 1.0 O A:GLU364 4.3 41.1 1.0 CZ2 A:TRP284 4.3 30.9 1.0 CZ3 A:TRP284 4.5 31.3 1.0 CB A:GLU364 4.6 45.1 1.0 N7 A:EHW401 4.7 32.7 1.0 C A:GLU364 4.8 44.9 1.0 CA A:GLN367 4.8 39.2 1.0 OE1 A:GLN367 4.9 70.3 1.0 O A:ARG363 5.0 55.1 1.0

J.Boettcher, B.J.Muellauer, A.Weiss-Puxbaum, A.Zoephel. X-Ray Structure of NSD3-PWWP1 in Complex with Compound 14 To Be Published.