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Atomistry » Fluorine » PDB 6gqy-6hay » 6gx8 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 6gqy-6hay » 6gx8 » |
Fluorine in PDB 6gx8: Alpha-Galactosidase From Thermotoga Maritima in Complex with Hydrolysed Cyclohexene-Based Carbasugar Mimic of GalactoseEnzymatic activity of Alpha-Galactosidase From Thermotoga Maritima in Complex with Hydrolysed Cyclohexene-Based Carbasugar Mimic of Galactose
All present enzymatic activity of Alpha-Galactosidase From Thermotoga Maritima in Complex with Hydrolysed Cyclohexene-Based Carbasugar Mimic of Galactose:
3.2.1.22; Protein crystallography data
The structure of Alpha-Galactosidase From Thermotoga Maritima in Complex with Hydrolysed Cyclohexene-Based Carbasugar Mimic of Galactose, PDB code: 6gx8
was solved by
T.M.Gloster,
V.Oehler,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6gx8:
The structure of Alpha-Galactosidase From Thermotoga Maritima in Complex with Hydrolysed Cyclohexene-Based Carbasugar Mimic of Galactose also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Alpha-Galactosidase From Thermotoga Maritima in Complex with Hydrolysed Cyclohexene-Based Carbasugar Mimic of Galactose
(pdb code 6gx8). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Alpha-Galactosidase From Thermotoga Maritima in Complex with Hydrolysed Cyclohexene-Based Carbasugar Mimic of Galactose, PDB code: 6gx8: Fluorine binding site 1 out of 1 in 6gx8Go back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Alpha-Galactosidase From Thermotoga Maritima in Complex with Hydrolysed Cyclohexene-Based Carbasugar Mimic of Galactose
![]() Mono view ![]() Stereo pair view
Reference:
W.Ren,
R.Pengelly,
M.Farren-Dai,
S.Shamsi Kazem Abadi,
V.Oehler,
O.Akintola,
J.Draper,
M.Meanwell,
S.Chakladar,
K.Swiderek,
V.Moliner,
R.Britton,
T.M.Gloster,
A.J.Bennet.
Revealing the Mechanism For Covalent Inhibition of Glycoside Hydrolases By Carbasugars at An Atomic Level. Nat Commun V. 9 3243 2018.
Page generated: Tue Jul 15 12:03:53 2025
ISSN: ESSN 2041-1723 PubMed: 30104598 DOI: 10.1038/S41467-018-05702-7 |
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