Fluorine in PDB 6hmo: Solution Structure of the Rna Duplex Formed By the 5'-End of U1SNRNA and the 5'-Splice Site of SMN2 EXON7 in Complex with the Smn-C5 Splicing Modifier

The binding sites of Fluorine atom in the Solution Structure of the Rna Duplex Formed By the 5'-End of U1SNRNA and the 5'-Splice Site of SMN2 EXON7 in Complex with the Smn-C5 Splicing Modifier (pdb code 6hmo). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Solution Structure of the Rna Duplex Formed By the 5'-End of U1SNRNA and the 5'-Splice Site of SMN2 EXON7 in Complex with the Smn-C5 Splicing Modifier, PDB code: 6hmo:

Fluorine binding site 1 out of 1 in the Solution Structure of the Rna Duplex Formed By the 5'-End of U1SNRNA and the 5'-Splice Site of SMN2 EXON7 in Complex with the Smn-C5 Splicing Modifier


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Solution Structure of the Rna Duplex Formed By the 5'-End of U1SNRNA and the 5'-Splice Site of SMN2 EXON7 in Complex with the Smn-C5 Splicing Modifier within 5.0Å range: probe atom residue distance (Å) B Occ A:F101 b:0.0 occ:1.00 F4 A:GDZ101 0.0 0.0 1.0 C3 A:GDZ101 1.3 0.0 1.0 C5 A:GDZ101 2.4 0.0 1.0 C2 A:GDZ101 2.4 0.0 1.0 H2 A:GDZ101 2.6 0.0 1.0 N11 A:GDZ101 3.0 0.0 1.0 N6 A:GDZ101 3.6 0.0 1.0 C1 A:GDZ101 3.7 0.0 1.0 C7 A:GDZ101 4.1 0.0 1.0 C9 A:GDZ101 4.3 0.0 1.0 C8 A:GDZ101 4.6 0.0 1.0 C19 A:GDZ101 4.9 0.0 1.0

S.Campagne, S.Boigner, S.Rudisser, A.Moursy, A.Knorlein, J.Hall, H.Ratni, A.Clery, F.H.Allain. Structural Basis For Specific Rna Splicing Correction Induced By A Small Molecule To Be Published.