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Atomistry » Fluorine » PDB 6hmp-6i77 » 6i3s | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 6hmp-6i77 » 6i3s » |
Fluorine in PDB 6i3s: Crystal Structure of MDM2 in Complex with Compound 13.Enzymatic activity of Crystal Structure of MDM2 in Complex with Compound 13.
All present enzymatic activity of Crystal Structure of MDM2 in Complex with Compound 13.:
2.3.2.27; Protein crystallography data
The structure of Crystal Structure of MDM2 in Complex with Compound 13., PDB code: 6i3s
was solved by
G.Bader,
D.Kessler,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6i3s:
The structure of Crystal Structure of MDM2 in Complex with Compound 13. also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of MDM2 in Complex with Compound 13.
(pdb code 6i3s). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of MDM2 in Complex with Compound 13., PDB code: 6i3s: Fluorine binding site 1 out of 1 in 6i3sGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Crystal Structure of MDM2 in Complex with Compound 13.
![]() Mono view ![]() Stereo pair view
Reference:
A.Gollner,
H.Weinstabl,
J.E.Fuchs,
D.Rudolph,
G.Garavel,
K.S.Hofbauer,
J.Karolyi-Oezguer,
G.Gmaschitz,
W.Hela,
N.Kerres,
E.Grondal,
P.Werni,
J.Ramharter,
J.Broeker,
D.B.Mcconnell.
Targeted Synthesis of Complex Spiro[3H-Indole-3,2'-Pyrrolidin]-2(1H)-Ones By Intramolecular Cyclization of Azomethine Ylides: Highly Potent MDM2-P53 Inhibitors. Chemmedchem V. 14 88 2019.
Page generated: Thu Aug 1 21:21:35 2024
ISSN: ESSN 1860-7187 PubMed: 30458062 DOI: 10.1002/CMDC.201800617 |
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