Fluorine in PDB 6myp: Avian Mitochondrial Complex II with Ttfa (Thenoyltrifluoroacetone) Bound

All present enzymatic activity of Avian Mitochondrial Complex II with Ttfa (Thenoyltrifluoroacetone) Bound:
1.3.5.1;

The structure of Avian Mitochondrial Complex II with Ttfa (Thenoyltrifluoroacetone) Bound, PDB code: 6myp was solved by E.A.Berry, L.-S.Huang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.36 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	69.951, 84.303, 290.194, 90.00, 90.00, 90.00
R / Rfree (%)	23.5 / 25.9

The structure of Avian Mitochondrial Complex II with Ttfa (Thenoyltrifluoroacetone) Bound also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Potassium	(K)	1 atom
Iron	(Fe)	10 atoms

The binding sites of Fluorine atom in the Avian Mitochondrial Complex II with Ttfa (Thenoyltrifluoroacetone) Bound (pdb code 6myp). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Avian Mitochondrial Complex II with Ttfa (Thenoyltrifluoroacetone) Bound, PDB code: 6myp:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the Avian Mitochondrial Complex II with Ttfa (Thenoyltrifluoroacetone) Bound


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Avian Mitochondrial Complex II with Ttfa (Thenoyltrifluoroacetone) Bound within 5.0Å range: probe atom residue distance (Å) B Occ C:F202 b:51.4 occ:1.00 F1 C:TTF202 0.0 51.4 1.0 C8 C:TTF202 1.3 49.5 1.0 F3 C:TTF202 2.1 49.3 1.0 F2 C:TTF202 2.2 51.2 1.0 C7 C:TTF202 2.3 47.9 1.0 O2 C:TTF202 2.5 51.4 1.0 CD1 C:ILE27 3.3 52.4 1.0 C6 C:TTF202 3.7 45.0 1.0 CZ2 B:TRP173 4.1 36.0 1.0 CZ3 B:TRP172 4.2 38.8 1.0 CG1 C:ILE27 4.2 52.0 1.0 CB B:PRO169 4.3 36.3 1.0 CE C:MET36 4.3 39.8 1.0 CG B:PRO169 4.5 38.6 1.0 CE3 B:TRP172 4.6 38.2 1.0 C1 D:UNL204 4.7 46.6 1.0 CB C:ILE27 4.7 49.8 1.0 CH2 C:TRP32 4.8 67.1 1.0 C5 C:TTF202 4.8 40.6 1.0 CE2 B:TRP173 4.9 31.9 1.0 C2 D:UNL204 5.0 44.4 1.0 CH2 B:TRP173 5.0 37.6 1.0 NE1 B:TRP173 5.0 31.4 1.0

Fluorine binding site 2 out of 3 in the Avian Mitochondrial Complex II with Ttfa (Thenoyltrifluoroacetone) Bound


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Avian Mitochondrial Complex II with Ttfa (Thenoyltrifluoroacetone) Bound within 5.0Å range: probe atom residue distance (Å) B Occ C:F202 b:51.2 occ:1.00 F2 C:TTF202 0.0 51.2 1.0 C8 C:TTF202 1.3 49.5 1.0 F1 C:TTF202 2.2 51.4 1.0 F3 C:TTF202 2.2 49.3 1.0 C7 C:TTF202 2.3 47.9 1.0 C6 C:TTF202 2.9 45.0 1.0 O2 C:TTF202 3.3 51.4 1.0 CH2 C:TRP32 3.8 67.1 1.0 CB C:ILE40 4.1 46.4 1.0 C2 D:UNL204 4.2 44.4 1.0 CG1 C:ILE40 4.2 50.9 1.0 CD1 C:ILE40 4.3 51.2 1.0 CD1 C:ILE27 4.3 52.4 1.0 C5 C:TTF202 4.4 40.6 1.0 C1 D:UNL204 4.5 46.6 1.0 CZ2 C:TRP32 4.5 67.0 1.0 CZ3 C:TRP32 4.6 66.5 1.0 CG2 C:ILE40 4.7 46.7 1.0 CE C:MET36 4.8 39.8 1.0 O1 C:TTF202 5.0 36.9 1.0

Fluorine binding site 3 out of 3 in the Avian Mitochondrial Complex II with Ttfa (Thenoyltrifluoroacetone) Bound


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Avian Mitochondrial Complex II with Ttfa (Thenoyltrifluoroacetone) Bound within 5.0Å range: probe atom residue distance (Å) B Occ C:F202 b:49.3 occ:1.00 F3 C:TTF202 0.0 49.3 1.0 C8 C:TTF202 1.3 49.5 1.0 F1 C:TTF202 2.1 51.4 1.0 F2 C:TTF202 2.2 51.2 1.0 C7 C:TTF202 2.3 47.9 1.0 C6 C:TTF202 3.1 45.0 1.0 O2 C:TTF202 3.2 51.4 1.0 CE C:MET36 3.3 39.8 1.0 CG B:PRO169 3.6 38.6 1.0 CB B:PRO169 4.0 36.3 1.0 CH2 C:TRP32 4.2 67.1 1.0 CG C:MET36 4.3 36.0 1.0 C5 C:TTF202 4.3 40.6 1.0 CZ3 C:TRP32 4.5 66.5 1.0 CD1 C:ILE27 4.6 52.4 1.0 SD C:MET36 4.6 41.0 1.0 O1 C:TTF202 4.9 36.9 1.0 CZ2 C:TRP32 5.0 67.0 1.0

L.-S.Huang, E.A.Berry. Crystallographic Studies of the Binding of Ligands to the Ubiquinone-Binding Site of Mitochondrial Respiratory Complex II To Be Published.