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Fluorine in PDB 6v2u: Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib
Enzymatic activity of Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib
All present enzymatic activity of Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib:
2.7.11.1;
2.7.11.1;
Protein crystallography data
The structure of Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib, PDB code: 6v2u
was solved by
K.Li,
G.Gonzalez Del-Pino,
E.Park,
M.J.Eck,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 41.48 / 3.78 |
| Space group | P 41 21 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 89.618, 89.618, 164.583, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 28.1 / 30.9 |
Other elements in 6v2u:
The structure of Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib also contains other interesting chemical elements:
| Chlorine | (Cl) | 1 atom |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib
(pdb code 6v2u). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib, PDB code: 6v2u:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;
In total 6 binding sites of Fluorine where determined in the Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib, PDB code: 6v2u:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;
Fluorine binding site 1 out of 6 in 6v2u
Go back to
Fluorine Binding Sites List in 6v2u
Fluorine binding site 1 out
of 6 in the Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib within 5.0Å range:
|
Fluorine binding site 2 out of 6 in 6v2u
Go back to
Fluorine Binding Sites List in 6v2u
Fluorine binding site 2 out
of 6 in the Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib within 5.0Å range:
|
Fluorine binding site 3 out of 6 in 6v2u
Go back to
Fluorine Binding Sites List in 6v2u
Fluorine binding site 3 out
of 6 in the Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib within 5.0Å range:
|
Fluorine binding site 4 out of 6 in 6v2u
Go back to
Fluorine Binding Sites List in 6v2u
Fluorine binding site 4 out
of 6 in the Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib within 5.0Å range:
|
Fluorine binding site 5 out of 6 in 6v2u
Go back to
Fluorine Binding Sites List in 6v2u
Fluorine binding site 5 out
of 6 in the Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib within 5.0Å range:
|
Fluorine binding site 6 out of 6 in 6v2u
Go back to
Fluorine Binding Sites List in 6v2u
Fluorine binding site 6 out
of 6 in the Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib within 5.0Å range:
|
Reference:
K.Li,
G.Gonzalez Del-Pino,
E.Park,
M.J.Eck.
Crystal Structure of the Insect Cell-Expressed Wt-Braf Kinase in Complex with Dabrafenib To Be Published.
Page generated: Tue Jul 15 16:25:59 2025
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