Atomistry » Fluorine » PDB 6v34-6viw » 6vg0
Atomistry »
  Fluorine »
    PDB 6v34-6viw »
      6vg0 »

Fluorine in PDB 6vg0: Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056

Enzymatic activity of Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056

All present enzymatic activity of Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056:
1.1.1.42;

Protein crystallography data

The structure of Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056, PDB code: 6vg0 was solved by A.Padyana, L.Jin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 41.20 / 2.66
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 196.770, 89.160, 90.750, 90.00, 90.00, 90.00
R / Rfree (%) 20.6 / 26.4

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056 (pdb code 6vg0). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 9 binding sites of Fluorine where determined in the Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056, PDB code: 6vg0:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9;

Fluorine binding site 1 out of 9 in 6vg0

Go back to Fluorine Binding Sites List in 6vg0
Fluorine binding site 1 out of 9 in the Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F501

b:33.3
occ:0.44
 F27 B:QWM501 0.0 33.3 0.4
C22 B:QWM501 1.0 33.1 0.6
C26 B:QWM501 1.4 28.1 0.4
C20 B:QWM501 1.9 28.2 0.6
C24 B:QWM501 2.1 34.8 0.6
F28 B:QWM501 2.2 30.6 0.4
F29 B:QWM501 2.2 26.5 0.4
C19 B:QWM501 2.4 30.1 0.4
N18 B:QWM501 2.7 33.8 0.4
C19 B:QWM501 3.1 30.9 0.6
CA B:ASP273 3.3 25.8 1.0
C11 B:QWM501 3.3 35.3 0.6
OD1 B:ASP273 3.4 21.2 1.0
NE2 B:GLN277 3.4 36.9 0.6
CB B:ASP273 3.5 34.9 1.0
O B:ASP273 3.5 35.7 1.0
N18 B:QWM501 3.6 34.9 0.6
C20 B:QWM501 3.6 29.5 0.4
CG B:ASP273 3.8 30.9 1.0
C B:ASP273 3.8 36.0 1.0
CD1 B:ILE251 4.0 30.3 1.0
OE1 B:GLN277 4.0 39.7 0.4
C11 B:QWM501 4.1 35.2 0.4
CG B:GLN277 4.1 35.9 0.6
CD B:GLN277 4.3 38.4 0.6
CD B:GLN277 4.3 34.7 0.4
C26 B:QWM501 4.4 27.9 0.6
NE2 B:GLN277 4.4 29.9 0.4
CG1 B:ILE251 4.5 30.3 1.0
N B:ASP273 4.5 28.7 1.0
C06 B:QWM501 4.5 36.8 0.6
F29 B:QWM501 4.6 32.1 0.6
CB B:VAL276 4.7 29.4 1.0
C22 B:QWM501 4.7 30.6 0.4
F28 B:QWM501 4.8 25.7 0.6
N01 B:QWM501 4.8 36.7 0.4
N05 B:QWM501 4.8 36.5 0.6
CG2 B:VAL255 4.8 35.9 1.0
CG1 B:VAL276 4.8 40.4 1.0
CG1 A:VAL276 4.8 36.6 1.0
OD2 B:ASP273 4.8 41.1 1.0
O B:TYR272 4.9 27.0 1.0
C06 B:QWM501 4.9 37.0 0.4
C24 B:QWM501 4.9 33.0 0.4

Fluorine binding site 2 out of 9 in 6vg0

Go back to Fluorine Binding Sites List in 6vg0
Fluorine binding site 2 out of 9 in the Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F501

b:30.7
occ:0.56
 F27 B:QWM501 0.0 30.7 0.6
C22 B:QWM501 0.9 30.6 0.4
C26 B:QWM501 1.4 27.9 0.6
C20 B:QWM501 1.9 29.5 0.4
C24 B:QWM501 1.9 33.0 0.4
F28 B:QWM501 2.2 25.7 0.6
F29 B:QWM501 2.2 32.1 0.6
C19 B:QWM501 2.4 30.9 0.6
N18 B:QWM501 2.7 34.9 0.6
C19 B:QWM501 3.1 30.1 0.4
C11 B:QWM501 3.1 35.2 0.4
CA A:ASP273 3.3 30.7 1.0
OD1 A:ASP273 3.3 29.6 1.0
O A:ASP273 3.4 33.3 1.0
CB A:ASP273 3.4 28.4 1.0
N18 B:QWM501 3.5 33.8 0.4
C20 B:QWM501 3.6 28.2 0.6
NE2 A:GLN277 3.6 36.3 0.4
CG A:ASP273 3.7 29.6 1.0
C A:ASP273 3.8 32.4 1.0
NE2 A:GLN277 3.8 38.3 0.6
OE1 A:GLN277 3.9 33.3 0.4
CD1 A:ILE251 4.1 23.5 1.0
C11 B:QWM501 4.1 35.3 0.6
CD A:GLN277 4.1 36.1 0.4
CG1 A:VAL276 4.1 36.6 1.0
CB A:VAL276 4.3 35.9 1.0
C06 B:QWM501 4.3 37.0 0.4
C26 B:QWM501 4.4 28.1 0.4
CG1 A:ILE251 4.5 26.5 1.0
N A:ASP273 4.5 27.5 1.0
CG A:GLN277 4.6 37.4 0.6
CD A:GLN277 4.6 36.7 0.6
N05 B:QWM501 4.6 37.1 0.4
F29 B:QWM501 4.7 26.5 0.4
C22 B:QWM501 4.7 33.1 0.6
OD2 A:ASP273 4.8 34.9 1.0
F28 B:QWM501 4.8 30.6 0.4
N01 B:QWM501 4.8 37.6 0.6
O A:TYR272 4.8 28.7 1.0
CG1 A:VAL255 4.9 30.3 1.0
C24 B:QWM501 4.9 34.8 0.6
C06 B:QWM501 4.9 36.8 0.6

Fluorine binding site 3 out of 9 in 6vg0

Go back to Fluorine Binding Sites List in 6vg0
Fluorine binding site 3 out of 9 in the Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F501

b:30.6
occ:0.44
 F28 B:QWM501 0.0 30.6 0.4
C26 B:QWM501 1.4 28.1 0.4
C20 B:QWM501 1.8 28.2 0.6
C22 B:QWM501 2.0 33.1 0.6
F27 B:QWM501 2.2 33.3 0.4
F29 B:QWM501 2.2 26.5 0.4
C19 B:QWM501 2.4 30.1 0.4
C19 B:QWM501 2.9 30.9 0.6
OD1 B:ASP273 3.0 21.2 1.0
C20 B:QWM501 3.2 29.5 0.4
CG1 B:ILE251 3.2 30.3 1.0
N18 B:QWM501 3.2 33.8 0.4
C24 B:QWM501 3.2 34.8 0.6
F29 B:QWM501 3.4 32.1 0.6
OH A:TYR272 3.4 30.7 1.0
CG1 A:VAL276 3.4 36.6 1.0
CD1 B:ILE251 3.5 30.3 1.0
CE2 A:TYR272 3.6 31.6 1.0
CG2 A:VAL276 3.6 33.9 1.0
C26 B:QWM501 3.8 27.9 0.6
CZ A:TYR272 3.8 28.4 1.0
CG B:ASP273 3.8 30.9 1.0
N18 B:QWM501 3.9 34.9 0.6
CB A:VAL276 4.0 35.9 1.0
C11 B:QWM501 4.0 35.3 0.6
C22 B:QWM501 4.4 30.6 0.4
CB B:ASP273 4.4 34.9 1.0
C11 B:QWM501 4.4 35.2 0.4
CA B:ASP273 4.5 25.8 1.0
CB B:ILE251 4.6 24.0 1.0
F28 B:QWM501 4.6 25.7 0.6
CD2 A:TYR272 4.6 24.7 1.0
OD2 B:ASP273 4.7 41.1 1.0
F27 B:QWM501 4.8 30.7 0.6
CG2 B:VAL255 4.9 35.9 1.0
C24 B:QWM501 4.9 33.0 0.4
CG2 B:ILE251 4.9 26.2 1.0
CE1 A:TYR272 5.0 24.8 1.0

Fluorine binding site 4 out of 9 in 6vg0

Go back to Fluorine Binding Sites List in 6vg0
Fluorine binding site 4 out of 9 in the Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F501

b:25.7
occ:0.56
 F28 B:QWM501 0.0 25.7 0.6
C26 B:QWM501 1.4 27.9 0.6
C20 B:QWM501 1.7 29.5 0.4
C22 B:QWM501 1.8 30.6 0.4
F27 B:QWM501 2.2 30.7 0.6
F29 B:QWM501 2.2 32.1 0.6
C19 B:QWM501 2.4 30.9 0.6
C19 B:QWM501 2.8 30.1 0.4
C24 B:QWM501 3.0 33.0 0.4
OD1 A:ASP273 3.0 29.6 1.0
C20 B:QWM501 3.2 28.2 0.6
N18 B:QWM501 3.2 34.9 0.6
CG1 A:ILE251 3.3 26.5 1.0
F29 B:QWM501 3.5 26.5 0.4
CE2 B:TYR272 3.5 24.6 1.0
OH B:TYR272 3.5 24.6 1.0
CG1 B:VAL276 3.5 40.4 1.0
CD1 A:ILE251 3.7 23.5 1.0
N18 B:QWM501 3.7 33.8 0.4
C11 B:QWM501 3.7 35.2 0.4
CG A:ASP273 3.8 29.6 1.0
C26 B:QWM501 3.8 28.1 0.4
CZ B:TYR272 3.8 20.0 1.0
CG2 B:VAL276 3.9 29.2 1.0
CB B:VAL276 4.1 29.4 1.0
CB A:ASP273 4.4 28.4 1.0
C22 B:QWM501 4.4 33.1 0.6
C11 B:QWM501 4.4 35.3 0.6
CD2 B:TYR272 4.5 22.0 1.0
OD2 A:ASP273 4.5 34.9 1.0
CA A:ASP273 4.6 30.7 1.0
F28 B:QWM501 4.6 30.6 0.4
CB A:ILE251 4.7 20.6 1.0
F27 B:QWM501 4.8 33.3 0.4
C24 B:QWM501 4.9 34.8 0.6
CG1 A:VAL255 5.0 30.3 1.0
CG2 A:ILE251 5.0 23.4 1.0

Fluorine binding site 5 out of 9 in 6vg0

Go back to Fluorine Binding Sites List in 6vg0
Fluorine binding site 5 out of 9 in the Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F501

b:26.5
occ:0.44
 F29 B:QWM501 0.0 26.5 0.4
C26 B:QWM501 1.4 28.1 0.4
C20 B:QWM501 1.8 28.2 0.6
F28 B:QWM501 2.2 30.6 0.4
F27 B:QWM501 2.2 33.3 0.4
C19 B:QWM501 2.4 30.1 0.4
C22 B:QWM501 2.6 33.1 0.6
C20 B:QWM501 2.8 29.5 0.4
OD1 B:ASP273 2.8 21.2 1.0
C19 B:QWM501 2.9 30.9 0.6
F29 B:QWM501 3.1 32.1 0.6
CD2 B:TYR272 3.3 22.0 1.0
CA B:ASP273 3.3 25.8 1.0
C26 B:QWM501 3.3 27.9 0.6
CE2 B:TYR272 3.4 24.6 1.0
F28 B:QWM501 3.5 25.7 0.6
N18 B:QWM501 3.6 33.8 0.4
CE2 A:TYR272 3.6 31.6 1.0
CG B:ASP273 3.7 30.9 1.0
C24 B:QWM501 3.8 34.8 0.6
N B:ASP273 3.8 28.7 1.0
CB B:ASP273 3.9 34.9 1.0
O B:TYR272 4.0 27.0 1.0
N18 B:QWM501 4.0 34.9 0.6
C B:TYR272 4.1 26.1 1.0
C22 B:QWM501 4.1 30.6 0.4
OH A:TYR272 4.2 30.7 1.0
O B:ASP273 4.3 35.7 1.0
CB B:VAL276 4.3 29.4 1.0
C B:ASP273 4.3 36.0 1.0
CG B:TYR272 4.4 24.2 1.0
CZ A:TYR272 4.4 28.4 1.0
C11 B:QWM501 4.4 35.3 0.6
CG2 B:VAL276 4.5 29.2 1.0
CD2 A:TYR272 4.6 24.7 1.0
CG1 B:VAL276 4.6 40.4 1.0
CZ B:TYR272 4.6 20.0 1.0
C11 B:QWM501 4.7 35.2 0.4
F27 B:QWM501 4.7 30.7 0.6
C24 B:QWM501 4.9 33.0 0.4
OD2 B:ASP273 4.9 41.1 1.0
CB B:TYR272 4.9 28.3 1.0

Fluorine binding site 6 out of 9 in 6vg0

Go back to Fluorine Binding Sites List in 6vg0
Fluorine binding site 6 out of 9 in the Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F501

b:32.1
occ:0.56
 F29 B:QWM501 0.0 32.1 0.6
C26 B:QWM501 1.4 27.9 0.6
C20 B:QWM501 1.6 29.5 0.4
F28 B:QWM501 2.2 25.7 0.6
F27 B:QWM501 2.2 30.7 0.6
C22 B:QWM501 2.3 30.6 0.4
C19 B:QWM501 2.4 30.9 0.6
C19 B:QWM501 2.7 30.1 0.4
OD1 A:ASP273 2.8 29.6 1.0
C20 B:QWM501 2.8 28.2 0.6
F29 B:QWM501 3.1 26.5 0.4
C26 B:QWM501 3.2 28.1 0.4
CD2 A:TYR272 3.3 24.7 1.0
CE2 A:TYR272 3.3 31.6 1.0
F28 B:QWM501 3.4 30.6 0.4
CA A:ASP273 3.5 30.7 1.0
N18 B:QWM501 3.6 34.9 0.6
C24 B:QWM501 3.6 33.0 0.4
CE2 B:TYR272 3.6 24.6 1.0
CG A:ASP273 3.7 29.6 1.0
N18 B:QWM501 3.8 33.8 0.4
CB A:VAL276 3.9 35.9 1.0
CB A:ASP273 4.0 28.4 1.0
CG1 A:VAL276 4.0 36.6 1.0
CG2 A:VAL276 4.0 33.9 1.0
N A:ASP273 4.1 27.5 1.0
O A:TYR272 4.1 28.7 1.0
C22 B:QWM501 4.1 33.1 0.6
C11 B:QWM501 4.2 35.2 0.4
C A:TYR272 4.3 28.7 1.0
OH B:TYR272 4.4 24.6 1.0
O A:ASP273 4.4 33.3 1.0
CD2 B:TYR272 4.4 22.0 1.0
CG A:TYR272 4.4 30.1 1.0
C A:ASP273 4.5 32.4 1.0
CZ A:TYR272 4.5 28.4 1.0
CZ B:TYR272 4.5 20.0 1.0
F27 B:QWM501 4.6 33.3 0.4
C11 B:QWM501 4.7 35.3 0.6
OD2 A:ASP273 4.9 34.9 1.0
C24 B:QWM501 4.9 34.8 0.6

Fluorine binding site 7 out of 9 in 6vg0

Go back to Fluorine Binding Sites List in 6vg0
Fluorine binding site 7 out of 9 in the Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F501

b:40.9
occ:0.47
 F27 C:QWM501 0.0 40.9 0.5
C26 C:QWM501 1.4 42.4 0.5
F28 C:QWM501 2.2 37.1 0.5
F29 C:QWM501 2.2 46.9 0.5
C19 C:QWM501 2.4 47.3 0.5
N18 C:QWM501 2.7 53.2 0.5
CA C:ASP273 3.3 31.0 1.0
OD1 C:ASP273 3.3 33.5 1.0
OE1 C:GLN277 3.3 47.9 0.6
CB C:ASP273 3.5 33.5 1.0
O C:ASP273 3.5 43.7 1.0
C20 C:QWM501 3.6 44.8 0.5
CG C:ASP273 3.7 31.0 1.0
C C:ASP273 3.8 36.1 1.0
CG1 C:VAL276 4.0 48.7 1.0
C11 C:QWM501 4.0 55.2 0.5
CB C:VAL276 4.1 46.0 1.0
CD1 C:ILE251 4.2 34.2 1.0
CD C:GLN277 4.2 54.7 0.6
NE2 C:GLN277 4.3 55.7 0.4
CG C:GLN277 4.4 51.5 0.4
CG1 C:ILE251 4.5 37.7 1.0
N C:ASP273 4.5 33.4 1.0
NE2 C:GLN277 4.5 55.8 0.6
C22 C:QWM501 4.7 43.0 0.5
CD C:GLN277 4.7 56.0 0.4
N01 C:QWM501 4.7 55.1 0.5
O C:TYR272 4.8 37.1 1.0
OD2 C:ASP273 4.8 41.2 1.0
C24 C:QWM501 4.9 49.8 0.5
C06 C:QWM501 4.9 55.1 0.5
CG2 C:VAL276 4.9 41.0 1.0

Fluorine binding site 8 out of 9 in 6vg0

Go back to Fluorine Binding Sites List in 6vg0
Fluorine binding site 8 out of 9 in the Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F501

b:37.1
occ:0.47
 F28 C:QWM501 0.0 37.1 0.5
C26 C:QWM501 1.4 42.4 0.5
F29 C:QWM501 2.2 46.9 0.5
F27 C:QWM501 2.2 40.9 0.5
C19 C:QWM501 2.4 47.3 0.5
OD1 C:ASP273 2.9 33.5 1.0
CG1 C:ILE251 3.1 37.7 1.0
N18 C:QWM501 3.2 53.2 0.5
C20 C:QWM501 3.2 44.8 0.5
CD1 C:ILE251 3.5 34.2 1.0
CG C:ASP273 3.6 31.0 1.0
CB C:ASP273 4.2 33.5 1.0
CB C:ILE251 4.4 32.5 1.0
C11 C:QWM501 4.4 55.2 0.5
OD2 C:ASP273 4.4 41.2 1.0
C22 C:QWM501 4.4 43.0 0.5
CA C:ASP273 4.5 31.0 1.0
CG2 C:ILE251 4.6 42.8 1.0
C24 C:QWM501 4.9 49.8 0.5

Fluorine binding site 9 out of 9 in 6vg0

Go back to Fluorine Binding Sites List in 6vg0
Fluorine binding site 9 out of 9 in the Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with Nadph and Agi-15056 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F501

b:46.9
occ:0.47
 F29 C:QWM501 0.0 46.9 0.5
C26 C:QWM501 1.4 42.4 0.5
F28 C:QWM501 2.2 37.1 0.5
F27 C:QWM501 2.2 40.9 0.5
C19 C:QWM501 2.4 47.3 0.5
OD1 C:ASP273 2.7 33.5 1.0
C20 C:QWM501 2.8 44.8 0.5
CE2 C:TYR272 3.3 41.1 1.0
CD2 C:TYR272 3.3 33.4 1.0
N18 C:QWM501 3.6 53.2 0.5
CA C:ASP273 3.7 31.0 1.0
CG C:ASP273 3.7 31.0 1.0
C22 C:QWM501 4.1 43.0 0.5
CB C:ASP273 4.1 33.5 1.0
N C:ASP273 4.2 33.4 1.0
CB C:VAL276 4.2 46.0 1.0
CG2 C:VAL276 4.3 41.0 1.0
CG1 C:VAL276 4.3 48.7 1.0
O C:TYR272 4.4 37.1 1.0
CZ C:TYR272 4.4 37.8 1.0
C C:TYR272 4.5 35.8 1.0
CG C:TYR272 4.5 35.3 1.0
C11 C:QWM501 4.7 55.2 0.5
C C:ASP273 4.7 36.1 1.0
O C:ASP273 4.8 43.7 1.0
OD2 C:ASP273 4.8 41.2 1.0
C24 C:QWM501 4.9 49.8 0.5

Reference:

Z.Konteatis, E.Artin, B.Nicolay, K.Straley, A.K.Padyana, L.Jin, Y.Chen, R.Narayaraswamy, S.Tong, F.Wang, D.Zhou, D.Cui, Z.Cai, Z.Luo, C.Fang, H.Tang, X.Lv, R.Nagaraja, H.Yang, S.M.Su, Z.Sui, L.Dang, K.Yen, J.Popovici-Muller, P.Codega, C.Campos, I.K.Mellinghoff, S.Biller. Vorasidenib (Ag-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 For Treatment of Glioma Acs Med.Chem.Lett. 2020.
ISSN: ISSN 1948-5875
DOI: 10.1021/ACSMEDCHEMLETT.9B00509
Page generated: Fri Aug 2 03:01:25 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy