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Atomistry » Fluorine » PDB 6x3d-6xk9 » 6xdf | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 6x3d-6xk9 » 6xdf » |
Fluorine in PDB 6xdf: Crystal Structure of IRE1A in Complex with G-4100Enzymatic activity of Crystal Structure of IRE1A in Complex with G-4100
All present enzymatic activity of Crystal Structure of IRE1A in Complex with G-4100:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of IRE1A in Complex with G-4100, PDB code: 6xdf
was solved by
S.Steinbacher,
W.Wang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6xdf:
The structure of Crystal Structure of IRE1A in Complex with G-4100 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of IRE1A in Complex with G-4100
(pdb code 6xdf). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of IRE1A in Complex with G-4100, PDB code: 6xdf: Fluorine binding site 1 out of 1 in 6xdfGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Crystal Structure of IRE1A in Complex with G-4100
![]() Mono view ![]() Stereo pair view
Reference:
R.E.Beveridge,
H.A.Wallweber,
A.Ashkenazi,
M.Beresini,
K.R.Clark,
P.Gibbons,
E.Ghiro,
S.Kaufman,
A.Larivee,
M.Leblanc,
J.P.Leclerc,
A.Lemire,
C.Ly,
J.Rudolph,
J.B.Schwarz,
S.Srivastava,
W.Wang,
L.Zhao,
M.G.Braun.
Identification of Braf-Sparing Amino-Thienopyrimidines with Potent IRE1 Alpha Inhibitory Activity. Acs Med.Chem.Lett. V. 11 2389 2020.
Page generated: Tue Jul 15 17:22:13 2025
ISSN: ISSN 1948-5875 PubMed: 33335661 DOI: 10.1021/ACSMEDCHEMLETT.0C00344 |
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