Fluorine in PDB 6xg6: Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3

The structure of Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3 also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Potassium	(K)	2 atoms

The binding sites of Fluorine atom in the Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3 (pdb code 6xg6). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3, PDB code: 6xg6:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;

Fluorine binding site 1 out of 6 in the Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3 within 5.0Å range: probe atom residue distance (Å) B Occ A:F902 b:40.4 occ:1.00 F1 A:BEF902 0.0 40.4 1.0 BE A:BEF902 1.5 40.4 1.0 MG A:MG903 2.0 39.0 1.0 F3 A:BEF902 2.5 40.4 1.0 F2 A:BEF902 2.6 40.4 1.0 O1B A:ADP901 2.6 51.2 1.0 OE1 A:GLU115 3.1 38.7 1.0 O3A A:ADP901 3.1 51.2 1.0 PB A:ADP901 3.3 51.2 1.0 CA A:GLY204 3.3 39.7 1.0 N A:GLY204 3.4 39.7 1.0 O3B A:ADP901 3.5 51.2 1.0 NH1 A:ARG402 3.6 37.3 1.0 OD1 A:ASN119 3.9 41.6 1.0 NE A:ARG402 4.1 37.3 1.0 CD A:GLU115 4.1 38.7 1.0 O1A A:ADP901 4.2 51.2 1.0 CZ A:ARG402 4.2 37.3 1.0 PA A:ADP901 4.3 51.2 1.0 CA A:GLY199 4.3 40.0 1.0 OE2 A:GLU115 4.5 38.7 1.0 C A:GLY204 4.6 39.7 1.0 C A:VAL203 4.6 36.5 1.0 O2B A:ADP901 4.7 51.2 1.0 N A:VAL203 4.7 36.5 1.0 N A:GLY202 4.8 41.9 1.0 CG A:ASN119 4.9 41.6 1.0 N A:GLN200 4.9 37.1 1.0

Fluorine binding site 2 out of 6 in the Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3 within 5.0Å range: probe atom residue distance (Å) B Occ A:F902 b:40.4 occ:1.00 F2 A:BEF902 0.0 40.4 1.0 BE A:BEF902 1.6 40.4 1.0 F3 A:BEF902 2.5 40.4 1.0 F1 A:BEF902 2.6 40.4 1.0 N A:GLY204 3.2 39.7 1.0 CA A:GLY204 3.5 39.7 1.0 CD2 A:PHE201 3.6 36.3 1.0 CG2 A:VAL203 3.6 36.5 1.0 CB A:PHE201 3.7 36.3 1.0 OH A:TYR106 3.7 40.0 1.0 NE A:ARG402 3.8 37.3 1.0 OE1 A:GLU115 3.8 38.7 1.0 C A:VAL203 3.8 36.5 1.0 OE2 A:GLU115 3.9 38.7 1.0 N A:VAL203 3.9 36.5 1.0 NH1 A:ARG402 4.0 37.3 1.0 O1B A:ADP901 4.0 51.2 1.0 CG A:PHE201 4.1 36.3 1.0 CD A:GLU115 4.2 38.7 1.0 CA A:VAL203 4.3 36.5 1.0 CZ A:ARG402 4.3 37.3 1.0 O A:VAL203 4.4 36.5 1.0 O3A A:ADP901 4.5 51.2 1.0 N A:GLY202 4.5 41.9 1.0 CB A:VAL203 4.6 36.5 1.0 O A:LEU400 4.6 36.0 1.0 CA A:PHE201 4.6 36.3 1.0 MG A:MG903 4.6 39.0 1.0 N A:PHE201 4.6 36.3 1.0 CE2 A:PHE201 4.7 36.3 1.0 CG A:ARG402 4.7 37.3 1.0 CD A:ARG402 4.8 37.3 1.0 C A:PHE201 4.8 36.3 1.0 PB A:ADP901 5.0 51.2 1.0

Fluorine binding site 3 out of 6 in the Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3 within 5.0Å range: probe atom residue distance (Å) B Occ A:F902 b:40.4 occ:1.00 F3 A:BEF902 0.0 40.4 1.0 BE A:BEF902 1.5 40.4 1.0 O1B A:ADP901 2.3 51.2 1.0 NH1 A:ARG402 2.4 37.3 1.0 F2 A:BEF902 2.5 40.4 1.0 F1 A:BEF902 2.5 40.4 1.0 N A:PHE201 2.7 36.3 1.0 N A:GLN200 3.2 37.1 1.0 CB A:PHE201 3.3 36.3 1.0 CD2 A:PHE201 3.3 36.3 1.0 CA A:PHE201 3.4 36.3 1.0 CZ A:ARG402 3.5 37.3 1.0 N A:GLY202 3.5 41.9 1.0 CG A:PHE201 3.6 36.3 1.0 C A:GLN200 3.7 37.1 1.0 NE A:ARG402 3.7 37.3 1.0 PB A:ADP901 3.7 51.2 1.0 C A:PHE201 3.9 36.3 1.0 CA A:GLY199 3.9 40.0 1.0 CA A:GLN200 4.0 37.1 1.0 C A:GLY199 4.0 40.0 1.0 MG A:MG903 4.0 39.0 1.0 O3A A:ADP901 4.1 51.2 1.0 CE2 A:PHE201 4.3 36.3 1.0 CG A:GLN200 4.3 37.1 1.0 N A:VAL203 4.6 36.5 1.0 O3B A:ADP901 4.6 51.2 1.0 CA A:GLY202 4.6 41.9 1.0 NH2 A:ARG402 4.7 37.3 1.0 N A:GLY204 4.7 39.7 1.0 O2B A:ADP901 4.7 51.2 1.0 CB A:GLN200 4.8 37.1 1.0 CD1 A:PHE201 4.8 36.3 1.0 O A:GLN200 4.9 37.1 1.0 O A:ILE198 4.9 37.4 1.0

Fluorine binding site 4 out of 6 in the Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3 within 5.0Å range: probe atom residue distance (Å) B Occ B:F902 b:37.9 occ:1.00 F1 B:BEF902 0.0 37.9 1.0 BE B:BEF902 1.5 37.9 1.0 O3B B:ADP901 2.4 51.2 1.0 F3 B:BEF902 2.5 37.9 1.0 N B:PHE201 2.5 38.2 1.0 F2 B:BEF902 2.6 37.9 1.0 N B:GLN200 2.8 38.5 1.0 NH2 B:ARG402 3.0 37.7 1.0 N B:GLY202 3.2 40.1 1.0 O1B B:ADP901 3.2 51.2 1.0 PB B:ADP901 3.3 51.2 1.0 CA B:PHE201 3.3 38.2 1.0 C B:GLN200 3.5 38.5 1.0 CB B:PHE201 3.5 38.2 1.0 CA B:GLY199 3.5 38.6 1.0 C B:GLY199 3.5 38.6 1.0 CD2 B:PHE201 3.6 38.2 1.0 CA B:GLN200 3.7 38.5 1.0 C B:PHE201 3.7 38.2 1.0 CG B:PHE201 3.8 38.2 1.0 O3A B:ADP901 3.9 51.2 1.0 CZ B:ARG402 4.1 37.7 1.0 CA B:GLY202 4.3 40.1 1.0 NE B:ARG402 4.4 37.7 1.0 N B:VAL203 4.5 35.6 1.0 CG B:GLN200 4.6 38.5 1.0 N B:GLY204 4.6 36.9 1.0 CE2 B:PHE201 4.6 38.2 1.0 MG B:MG903 4.6 42.7 1.0 O2B B:ADP901 4.6 51.2 1.0 O B:GLN200 4.6 38.5 1.0 O B:GLY199 4.7 38.6 1.0 CB B:GLN200 4.7 38.5 1.0 O B:ILE198 4.7 39.6 1.0 N B:GLY199 4.8 38.6 1.0 C B:GLY202 4.9 40.1 1.0 O B:PHE201 4.9 38.2 1.0

Fluorine binding site 5 out of 6 in the Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3 within 5.0Å range: probe atom residue distance (Å) B Occ B:F902 b:37.9 occ:1.00 F2 B:BEF902 0.0 37.9 1.0 BE B:BEF902 1.6 37.9 1.0 O1B B:ADP901 2.3 51.2 1.0 F3 B:BEF902 2.5 37.9 1.0 MG B:MG903 2.5 42.7 1.0 F1 B:BEF902 2.6 37.9 1.0 OE2 B:GLU115 2.8 36.4 1.0 NH2 B:ARG402 3.4 37.7 1.0 PB B:ADP901 3.4 51.2 1.0 CA B:GLY204 3.5 36.9 1.0 O3B B:ADP901 3.7 51.2 1.0 N B:GLY204 3.8 36.9 1.0 OD1 B:ASN119 3.9 39.1 1.0 NE B:ARG402 3.9 37.7 1.0 O3A B:ADP901 3.9 51.2 1.0 CA B:GLY199 4.0 38.6 1.0 CD B:GLU115 4.0 36.4 1.0 CZ B:ARG402 4.1 37.7 1.0 O1A B:ADP901 4.2 51.2 1.0 N B:GLN200 4.7 38.5 1.0 C B:GLY204 4.7 36.9 1.0 O2B B:ADP901 4.7 51.2 1.0 PA B:ADP901 4.8 51.2 1.0 OE1 B:GLU115 4.8 36.4 1.0 N B:GLY199 4.9 38.6 1.0 CG B:ASN119 4.9 39.1 1.0 C B:GLY199 4.9 38.6 1.0 CD2 B:PHE201 4.9 38.2 1.0 C B:VAL203 5.0 35.6 1.0

Fluorine binding site 6 out of 6 in the Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Full-Length Human Mitochondrial HSP90 (TRAP1) with Adp-BEF3 within 5.0Å range: probe atom residue distance (Å) B Occ B:F902 b:37.9 occ:1.00 F3 B:BEF902 0.0 37.9 1.0 BE B:BEF902 1.5 37.9 1.0 F2 B:BEF902 2.5 37.9 1.0 F1 B:BEF902 2.5 37.9 1.0 N B:GLY204 2.9 36.9 1.0 CA B:GLY204 3.3 36.9 1.0 CD2 B:PHE201 3.5 38.2 1.0 CB B:PHE201 3.6 38.2 1.0 C B:VAL203 3.6 35.6 1.0 N B:VAL203 3.6 35.6 1.0 OE2 B:GLU115 3.7 36.4 1.0 CG2 B:VAL203 3.8 35.6 1.0 N B:GLY202 4.0 40.1 1.0 CG B:PHE201 4.0 38.2 1.0 O1B B:ADP901 4.1 51.2 1.0 CA B:VAL203 4.1 35.6 1.0 OH B:TYR106 4.1 38.8 1.0 NE B:ARG402 4.2 37.7 1.0 NH2 B:ARG402 4.2 37.7 1.0 O3B B:ADP901 4.3 51.2 1.0 MG B:MG903 4.3 42.7 1.0 N B:PHE201 4.3 38.2 1.0 CA B:PHE201 4.3 38.2 1.0 O B:VAL203 4.3 35.6 1.0 O3A B:ADP901 4.4 51.2 1.0 C B:PHE201 4.4 38.2 1.0 PB B:ADP901 4.5 51.2 1.0 CB B:VAL203 4.6 35.6 1.0 C B:GLY202 4.6 40.1 1.0 CE2 B:PHE201 4.7 38.2 1.0 CZ B:ARG402 4.7 37.7 1.0 CD B:GLU115 4.8 36.4 1.0 C B:GLY204 4.8 36.9 1.0 CA B:GLY202 4.8 40.1 1.0

F.Wang, Y.Liu, Z.Yu, S.Li, S.Feng, Y.Cheng, D.A.Agard. General and Robust Covalently Linked Graphene Oxide Affinity Grids For High-Resolution Cryo-Em. Proc.Natl.Acad.Sci.Usa V. 117 24269 2020.
ISSN: ESSN 1091-6490
PubMed: 32913054
DOI: 10.1073/PNAS.2009707117