Fluorine in PDB 6xi8: Yeast Tfiik (KIN28/CCL1/TFB3) Complex

All present enzymatic activity of Yeast Tfiik (KIN28/CCL1/TFB3) Complex:
2.7.11.23;

The structure of Yeast Tfiik (KIN28/CCL1/TFB3) Complex also contains other interesting chemical elements:

Aluminium

(Al)

1 atom

The binding sites of Fluorine atom in the Yeast Tfiik (KIN28/CCL1/TFB3) Complex (pdb code 6xi8). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Yeast Tfiik (KIN28/CCL1/TFB3) Complex, PDB code: 6xi8:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the Yeast Tfiik (KIN28/CCL1/TFB3) Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Yeast Tfiik (KIN28/CCL1/TFB3) Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:F402 b:107.3 occ:1.00 F1 A:AF3402 0.0 107.3 1.0 AL A:AF3402 1.7 107.3 1.0 F3 A:AF3402 3.0 107.3 1.0 F2 A:AF3402 3.0 107.3 1.0 O1A A:ADP401 3.5 105.6 1.0 O3' A:ADP401 3.7 105.6 1.0 C3' A:ADP401 4.2 105.6 1.0 C4' A:ADP401 4.3 105.6 1.0 O1B A:ADP401 4.4 105.6 1.0 O5' A:ADP401 4.4 105.6 1.0 PA A:ADP401 4.5 105.6 1.0 C5' A:ADP401 4.5 105.6 1.0 O3A A:ADP401 5.0 105.6 1.0

Fluorine binding site 2 out of 3 in the Yeast Tfiik (KIN28/CCL1/TFB3) Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Yeast Tfiik (KIN28/CCL1/TFB3) Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:F402 b:107.3 occ:1.00 F2 A:AF3402 0.0 107.3 1.0 AL A:AF3402 1.7 107.3 1.0 F1 A:AF3402 3.0 107.3 1.0 F3 A:AF3402 3.0 107.3 1.0 O1B A:ADP401 3.1 105.6 1.0 ND2 A:ASN133 3.6 72.6 1.0 NZ A:LYS131 4.4 73.4 1.0 CG A:ASN133 4.4 72.6 1.0 PB A:ADP401 4.5 105.6 1.0 O1A A:ADP401 4.5 105.6 1.0 O3A A:ADP401 4.8 105.6 1.0 CB A:ASN133 5.0 72.6 1.0

Fluorine binding site 3 out of 3 in the Yeast Tfiik (KIN28/CCL1/TFB3) Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Yeast Tfiik (KIN28/CCL1/TFB3) Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:F402 b:107.3 occ:1.00 F3 A:AF3402 0.0 107.3 1.0 AL A:AF3402 1.7 107.3 1.0 O3' A:ADP401 2.8 105.6 1.0 F1 A:AF3402 3.0 107.3 1.0 F2 A:AF3402 3.0 107.3 1.0 C3' A:ADP401 3.4 105.6 1.0 O2' A:ADP401 4.4 105.6 1.0 C2' A:ADP401 4.5 105.6 1.0 C4' A:ADP401 4.6 105.6 1.0

T.Van Eeuwen, T.Li, H.J.Kim, J.J.Gorbea Colon, M.I.Parker, R.L.Dunbrack, B.A.Garcia, K.L.Tsai, K.Murakami. Structure of Tfiik For Phosphorylation of Ctd of Rna Polymerase II. Sci Adv V. 7 2021.
ISSN: ESSN 2375-2548
PubMed: 33827808
DOI: 10.1126/SCIADV.ABD4420