Atomistry » Fluorine » PDB 6xl4-6y8n » 6xv1
Atomistry »
  Fluorine »
    PDB 6xl4-6y8n »
      6xv1 »

Fluorine in PDB 6xv1: Human SIRT6 13-308 in Complex with Adp-Ribose and the Activator Mdl- 801

Enzymatic activity of Human SIRT6 13-308 in Complex with Adp-Ribose and the Activator Mdl- 801

All present enzymatic activity of Human SIRT6 13-308 in Complex with Adp-Ribose and the Activator Mdl- 801:
2.3.1.286;

Protein crystallography data

The structure of Human SIRT6 13-308 in Complex with Adp-Ribose and the Activator Mdl- 801, PDB code: 6xv1 was solved by W.You, C.Steegborn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 45.59 / 1.95
Space group P 63
Cell size a, b, c (Å), α, β, γ (°) 91.175, 91.175, 143.584, 90.00, 90.00, 120.00
R / Rfree (%) 15 / 16.5

Other elements in 6xv1:

The structure of Human SIRT6 13-308 in Complex with Adp-Ribose and the Activator Mdl- 801 also contains other interesting chemical elements:

Zinc (Zn) 2 atoms
Bromine (Br) 1 atom
Chlorine (Cl) 2 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Human SIRT6 13-308 in Complex with Adp-Ribose and the Activator Mdl- 801 (pdb code 6xv1). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Human SIRT6 13-308 in Complex with Adp-Ribose and the Activator Mdl- 801, PDB code: 6xv1:

Fluorine binding site 1 out of 1 in 6xv1

Go back to Fluorine Binding Sites List in 6xv1
Fluorine binding site 1 out of 1 in the Human SIRT6 13-308 in Complex with Adp-Ribose and the Activator Mdl- 801


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human SIRT6 13-308 in Complex with Adp-Ribose and the Activator Mdl- 801 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F403

b:64.7
occ:1.00
 F1 A:8L9403 0.0 64.7 1.0
C39 A:8L9403 1.4 69.2 1.0
C38 A:8L9403 2.4 66.2 1.0
C40 A:8L9403 2.4 65.3 1.0
BR1 A:8L9403 3.0 54.3 1.0
CG2 A:VAL115 3.4 23.7 1.0
C42 A:8L9403 3.6 70.1 1.0
C36 A:8L9403 3.7 67.6 1.0
CZ A:PHE86 3.8 39.9 1.0
CE1 A:PHE86 3.8 36.5 1.0
C35 A:8L9403 4.1 76.9 1.0
CZ A:PHE64 4.2 27.9 1.0
N A:ASP116 4.5 23.4 1.0
CB A:ASP116 4.6 25.8 1.0
CE2 A:PHE64 4.6 30.0 1.0
CA A:ASP116 4.6 23.6 1.0
CG2 A:ILE61 4.7 31.0 1.0
CB A:VAL115 4.8 23.0 1.0
C A:VAL115 4.8 19.6 1.0
C43 A:8L9403 4.9 72.6 1.0
N A:VAL115 4.9 22.8 1.0
CE2 A:PHE86 5.0 37.0 1.0

Reference:

W.You, C.Steegborn. Crystal Structures of SIRT6 Complexes with the Allosteric Activator Mdl-801 Reveal Binding Site and Interaction Details To Be Published.
Page generated: Tue Jul 15 17:33:19 2025

Last articles

Mg in 9F37
Mg in 9EZL
Mg in 9F28
Mg in 9F2R
Mg in 9F12
Mg in 9F11
Mg in 9F10
Mg in 9F0Z
Mg in 9F0Y
Mg in 9F07
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy