|
Atomistry » Fluorine » PDB 6yhc-6z4b » 6yti | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 6yhc-6z4b » 6yti » |
Fluorine in PDB 6yti: CLK1 Bound with ETH1610 (Cpd 17)Enzymatic activity of CLK1 Bound with ETH1610 (Cpd 17)
All present enzymatic activity of CLK1 Bound with ETH1610 (Cpd 17):
2.7.12.1; Protein crystallography data
The structure of CLK1 Bound with ETH1610 (Cpd 17), PDB code: 6yti
was solved by
M.Schroeder,
A.Chaikuad,
S.Knapp,
Structural Genomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the CLK1 Bound with ETH1610 (Cpd 17)
(pdb code 6yti). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the CLK1 Bound with ETH1610 (Cpd 17), PDB code: 6yti: Fluorine binding site 1 out of 1 in 6ytiGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the CLK1 Bound with ETH1610 (Cpd 17)
![]() Mono view ![]() Stereo pair view
Reference:
M.Schroder,
A.N.Bullock,
O.Fedorov,
F.Bracher,
A.Chaikuad,
S.Knapp.
Dfg-1 Residue Controls Inhibitor Binding Mode and Affinity, Providing A Basis For Rational Design of Kinase Inhibitor Selectivity. J.Med.Chem. V. 63 10224 2020.
Page generated: Fri Aug 2 04:46:34 2024
ISSN: ISSN 0022-2623 PubMed: 32787076 DOI: 10.1021/ACS.JMEDCHEM.0C00898 |
Last articlesCl in 3L28Cl in 3L27 Cl in 3L29 Cl in 3L26 Cl in 3L25 Cl in 3L12 Cl in 3L21 Cl in 3L1S Cl in 3L1R Cl in 3L14 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |