Fluorine in PDB 6zcu: Syk in Complex with 57262_SYKB-AZ13344324-2

All present enzymatic activity of Syk in Complex with 57262_SYKB-AZ13344324-2:
2.7.10.2;

The structure of Syk in Complex with 57262_SYKB-AZ13344324-2, PDB code: 6zcu was solved by J.A.Read, J.Patel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	60.26 / 1.73
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	39.46, 82.791, 87.876, 90, 90, 90
R / Rfree (%)	18.8 / 21.8

The structure of Syk in Complex with 57262_SYKB-AZ13344324-2 also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Fluorine atom in the Syk in Complex with 57262_SYKB-AZ13344324-2 (pdb code 6zcu). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Syk in Complex with 57262_SYKB-AZ13344324-2, PDB code: 6zcu:

Fluorine binding site 1 out of 1 in the Syk in Complex with 57262_SYKB-AZ13344324-2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Syk in Complex with 57262_SYKB-AZ13344324-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:F701 b:32.6 occ:1.00 F11 A:5JG701 0.0 32.6 1.0 C6 A:5JG701 1.4 30.5 1.0 C7 A:5JG701 2.3 32.3 1.0 C5 A:5JG701 2.4 27.8 1.0 N13 A:5JG701 2.7 25.1 1.0 O A:ALA451 2.8 28.1 1.0 C12 A:5JG701 2.8 25.3 1.0 O A:GLU452 3.1 26.8 1.0 C A:GLU452 3.4 29.5 1.0 N A:GLY454 3.4 27.1 1.0 CA A:GLY454 3.6 26.2 1.0 C8 A:5JG701 3.6 34.1 1.0 C4 A:5JG701 3.6 28.2 1.0 CA A:GLU452 3.7 26.8 1.0 C A:ALA451 3.8 28.2 1.0 C14 A:5JG701 4.0 24.1 1.0 N A:LEU453 4.1 26.6 1.0 C3 A:5JG701 4.1 31.9 1.0 SD A:MET450 4.1 38.2 1.0 N16 A:5JG701 4.1 21.6 1.0 C A:LEU453 4.2 31.5 1.0 N A:GLU452 4.2 27.3 1.0 CD2 A:LEU377 4.5 30.6 1.0 CA A:LEU453 4.6 26.6 1.0 C15 A:5JG701 4.7 23.2 1.0 O9 A:5JG701 4.8 37.7 1.0 N20 A:5JG701 4.8 25.3 1.0 O A:LEU453 4.9 31.3 1.0

J.A.Read, J.A.Read, J.Patel. N/A N/A.