Fluorine in PDB 7axx: Structure of WDR5:Cs-VIP8 Crystal After Illumination at 405 Nm and Room Temperature

The structure of Structure of WDR5:Cs-VIP8 Crystal After Illumination at 405 Nm and Room Temperature, PDB code: 7axx was solved by L.Werel, L.-O.Essen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.01 / 1.79
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	46.03, 46.9, 126.32, 90, 90, 90
R / Rfree (%)	16.6 / 21.4

The binding sites of Fluorine atom in the Structure of WDR5:Cs-VIP8 Crystal After Illumination at 405 Nm and Room Temperature (pdb code 7axx). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Structure of WDR5:Cs-VIP8 Crystal After Illumination at 405 Nm and Room Temperature, PDB code: 7axx:
Jump to Fluorine binding site number: 1; 2; 3; 4;

Fluorine binding site 1 out of 4 in the Structure of WDR5:Cs-VIP8 Crystal After Illumination at 405 Nm and Room Temperature


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of WDR5:Cs-VIP8 Crystal After Illumination at 405 Nm and Room Temperature within 5.0Å range: probe atom residue distance (Å) B Occ B:F103 b:55.5 occ:1.00 FA2 B:S7Z103 0.0 55.5 1.0 CA2 B:S7Z103 1.4 52.4 1.0 CA3 B:S7Z103 2.3 49.6 1.0 CA1 B:S7Z103 2.4 52.3 1.0 NA1 B:S7Z103 2.9 55.5 1.0 CA4 B:S7Z103 3.6 46.6 1.0 CA6 B:S7Z103 3.7 49.8 1.0 FB2 B:S7Z103 3.8 56.9 1.0 NB1 B:S7Z103 3.9 56.0 1.0 CA5 B:S7Z103 4.1 47.0 1.0 CB2 B:S7Z103 4.6 54.2 1.0 CB1 B:S7Z103 4.7 54.5 1.0 FA6 B:S7Z103 4.8 50.2 1.0 CA B:S7Z103 4.8 43.6 1.0

Fluorine binding site 2 out of 4 in the Structure of WDR5:Cs-VIP8 Crystal After Illumination at 405 Nm and Room Temperature


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of WDR5:Cs-VIP8 Crystal After Illumination at 405 Nm and Room Temperature within 5.0Å range: probe atom residue distance (Å) B Occ B:F103 b:50.2 occ:1.00 FA6 B:S7Z103 0.0 50.2 1.0 CA6 B:S7Z103 1.4 49.8 1.0 CA5 B:S7Z103 2.4 47.0 1.0 CA1 B:S7Z103 2.4 52.3 1.0 NA1 B:S7Z103 2.9 55.5 1.0 FB6 B:S7Z103 3.1 54.7 1.0 CB6 B:S7Z103 3.1 53.3 1.0 CB1 B:S7Z103 3.2 54.5 1.0 NB1 B:S7Z103 3.3 56.0 1.0 CD1 B:DPN5 3.4 41.2 1.0 CE1 B:DPN5 3.4 42.4 1.0 CA2 B:S7Z103 3.7 52.4 1.0 CA4 B:S7Z103 3.7 46.6 1.0 CB5 B:S7Z103 3.9 51.6 1.0 CB2 B:S7Z103 4.1 54.2 1.0 CA3 B:S7Z103 4.2 49.6 1.0 CG B:DPN5 4.2 39.7 1.0 CZ B:DPN5 4.2 42.0 1.0 CB4 B:S7Z103 4.6 51.2 1.0 CB3 B:S7Z103 4.7 52.3 1.0 FB2 B:S7Z103 4.8 56.9 1.0 FA2 B:S7Z103 4.8 55.5 1.0 CD2 B:DPN5 4.8 39.0 1.0 CE2 B:DPN5 4.8 40.2 1.0 CB B:DPN5 4.9 39.3 1.0 CA B:S7Z103 4.9 43.6 1.0

Fluorine binding site 3 out of 4 in the Structure of WDR5:Cs-VIP8 Crystal After Illumination at 405 Nm and Room Temperature


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structure of WDR5:Cs-VIP8 Crystal After Illumination at 405 Nm and Room Temperature within 5.0Å range: probe atom residue distance (Å) B Occ B:F103 b:56.9 occ:1.00 FB2 B:S7Z103 0.0 56.9 1.0 CB2 B:S7Z103 1.4 54.2 1.0 CB1 B:S7Z103 2.4 54.5 1.0 CB3 B:S7Z103 2.4 52.3 1.0 NB1 B:S7Z103 2.7 56.0 1.0 NA1 B:S7Z103 3.3 55.5 1.0 CA1 B:S7Z103 3.5 52.3 1.0 CB6 B:S7Z103 3.6 53.3 1.0 CB4 B:S7Z103 3.7 51.2 1.0 CA2 B:S7Z103 3.7 52.4 1.0 FA2 B:S7Z103 3.8 55.5 1.0 CB5 B:S7Z103 4.1 51.6 1.0 CA6 B:S7Z103 4.3 49.8 1.0 CA3 B:S7Z103 4.6 49.6 1.0 FB6 B:S7Z103 4.7 54.7 1.0 FA6 B:S7Z103 4.8 50.2 1.0 CB B:S7Z103 4.9 50.4 1.0

Fluorine binding site 4 out of 4 in the Structure of WDR5:Cs-VIP8 Crystal After Illumination at 405 Nm and Room Temperature


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Structure of WDR5:Cs-VIP8 Crystal After Illumination at 405 Nm and Room Temperature within 5.0Å range: probe atom residue distance (Å) B Occ B:F103 b:54.7 occ:1.00 FB6 B:S7Z103 0.0 54.7 1.0 CB6 B:S7Z103 1.4 53.3 1.0 CB5 B:S7Z103 2.4 51.6 1.0 CB1 B:S7Z103 2.4 54.5 1.0 NB1 B:S7Z103 2.9 56.0 1.0 FA6 B:S7Z103 3.1 50.2 1.0 CB2 B:S7Z103 3.6 54.2 1.0 CB4 B:S7Z103 3.7 51.2 1.0 NA1 B:S7Z103 3.7 55.5 1.0 CA6 B:S7Z103 4.1 49.8 1.0 CB3 B:S7Z103 4.1 52.3 1.0 CA1 B:S7Z103 4.4 52.3 1.0 FB2 B:S7Z103 4.7 56.9 1.0 CD1 B:DPN5 4.9 41.2 1.0 CB B:S7Z103 4.9 50.4 1.0 CE1 B:DPN5 4.9 42.4 1.0

L.Albert, J.Nagpal, W.Steinchen, L.Zhang, L.Werel, N.Djokovic, D.Ruzic, M.Hoffarth, J.Xu, J.Kaspareit, F.Abendroth, A.Royant, G.Bange, K.Nikolic, S.Ryu, Y.Dou, L.-O.Essen, O.Vazquez. Bistable Photoswitch Allows in Vivo Control of Hematopoiesis To Be Published.