Fluorine in PDB 7e14: COMPOUND2_GLP-1R_OWL833_GS Complex Structure

The structure of COMPOUND2_GLP-1R_OWL833_GS Complex Structure also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Fluorine atom in the COMPOUND2_GLP-1R_OWL833_GS Complex Structure (pdb code 7e14). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the COMPOUND2_GLP-1R_OWL833_GS Complex Structure, PDB code: 7e14:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the COMPOUND2_GLP-1R_OWL833_GS Complex Structure


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of COMPOUND2_GLP-1R_OWL833_GS Complex Structure within 5.0Å range: probe atom residue distance (Å) B Occ R:F501 b:38.7 occ:1.00 F01 R:V6G501 0.0 38.7 1.0 C27 R:V6G501 1.4 38.7 1.0 C28 R:V6G501 2.5 38.7 1.0 C26 R:V6G501 2.5 38.7 1.0 C32 R:V6G501 3.0 38.7 1.0 C33 R:V6G501 3.0 38.7 1.0 CE1 R:TYR148 3.1 28.4 1.0 CG R:LEU144 3.3 37.5 1.0 CD2 R:LEU144 3.4 37.5 1.0 N R:TYR145 3.6 32.2 1.0 OH R:TYR148 3.7 28.4 1.0 O R:LEU141 3.8 47.0 1.0 CZ R:TYR148 3.8 28.4 1.0 CA R:TYR145 3.8 32.2 1.0 C24 R:V6G501 3.9 38.7 1.0 C25 R:V6G501 3.9 38.7 1.0 CB R:LEU144 3.9 37.5 1.0 CB R:LEU141 3.9 47.0 1.0 C R:LEU144 4.0 37.5 1.0 CD1 R:TYR148 4.1 28.4 1.0 CB R:TYR145 4.1 32.2 1.0 CD1 R:LEU141 4.2 47.0 1.0 C23 R:V6G501 4.4 38.7 1.0 O R:LEU144 4.5 37.5 1.0 CD1 R:LEU144 4.5 37.5 1.0 CA R:LEU144 4.6 37.5 1.0 CG R:LEU141 4.7 47.0 1.0 C R:LEU141 4.8 47.0 1.0

Fluorine binding site 2 out of 2 in the COMPOUND2_GLP-1R_OWL833_GS Complex Structure


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of COMPOUND2_GLP-1R_OWL833_GS Complex Structure within 5.0Å range: probe atom residue distance (Å) B Occ R:F501 b:38.7 occ:1.00 F02 R:V6G501 0.0 38.7 1.0 C35 R:V6G501 1.4 38.7 1.0 C34 R:V6G501 2.5 38.7 1.0 C39 R:V6G501 2.5 38.7 1.0 OD1 R:ASP198 2.7 31.4 1.0 N08 R:V6G501 3.0 38.7 1.0 C30 R:V6G501 3.2 38.7 1.0 C40 R:V6G501 3.3 38.7 1.0 CE1 R:TYR145 3.3 32.2 1.0 CG R:ASP198 3.3 31.4 1.0 CD1 R:TYR145 3.5 32.2 1.0 C38 R:V6G501 3.9 38.7 1.0 C36 R:V6G501 3.9 38.7 1.0 OD2 R:ASP198 3.9 31.4 1.0 OH R:TYR148 4.1 28.4 1.0 CB R:ASP198 4.1 31.4 1.0 C29 R:V6G501 4.1 38.7 1.0 CZ R:TYR145 4.3 32.2 1.0 CA R:ASP198 4.3 31.4 1.0 C37 R:V6G501 4.4 38.7 1.0 C31 R:V6G501 4.4 38.7 1.0 CG R:TYR145 4.6 32.2 1.0 N10 R:V6G501 4.6 38.7 1.0 OH R:TYR145 4.8 32.2 1.0 O04 R:V6G501 4.8 38.7 1.0 N09 R:V6G501 4.8 38.7 1.0 N07 R:V6G501 4.9 38.7 1.0

Z.Cong, L.N.Chen, H.Ma, Q.Zhou, X.Zou, C.Ye, A.Dai, Q.Liu, W.Huang, X.Sun, X.Wang, P.Xu, L.Zhao, T.Xia, W.Zhong, D.Yang, H.Eric Xu, Y.Zhang, M.W.Wang. Molecular Insights Into Ago-Allosteric Modulation of the Human Glucagon-Like Peptide-1 Receptor. Nat Commun V. 12 3763 2021.
ISSN: ESSN 2041-1723
PubMed: 34145245
DOI: 10.1038/S41467-021-24058-Z