|
Atomistry » Fluorine » PDB 7k6z-7kpb » 7kko | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 7k6z-7kpb » 7kko » |
Fluorine in PDB 7kko: Structure of the Catalytic Domain of Tankyrase 1 in Complex with OlaparibProtein crystallography data
The structure of Structure of the Catalytic Domain of Tankyrase 1 in Complex with Olaparib, PDB code: 7kko
was solved by
K.S.Gajiwala,
K.Ryan,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7kko:
The structure of Structure of the Catalytic Domain of Tankyrase 1 in Complex with Olaparib also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of the Catalytic Domain of Tankyrase 1 in Complex with Olaparib
(pdb code 7kko). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Structure of the Catalytic Domain of Tankyrase 1 in Complex with Olaparib, PDB code: 7kko: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 7kkoGo back to![]() ![]()
Fluorine binding site 1 out
of 3 in the Structure of the Catalytic Domain of Tankyrase 1 in Complex with Olaparib
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 3 in 7kkoGo back to![]() ![]()
Fluorine binding site 2 out
of 3 in the Structure of the Catalytic Domain of Tankyrase 1 in Complex with Olaparib
![]() Mono view ![]() Stereo pair view
Fluorine binding site 3 out of 3 in 7kkoGo back to![]() ![]()
Fluorine binding site 3 out
of 3 in the Structure of the Catalytic Domain of Tankyrase 1 in Complex with Olaparib
![]() Mono view ![]() Stereo pair view
Reference:
K.Ryan,
B.Bolanos,
M.Smith,
P.Palde,
P.D.Cuenca,
T.L.Vanarsdale,
S.Niessen,
L.Zhang,
D.Behenna,
M.A.Ornelas,
K.T.Tran,
S.Kaiser,
L.Lum,
A.Stewart,
K.S.Gajiwala.
Dissecting the Molecular Determinants of Clinical PARP1 Inhibitor Selectivity For TANKYRASE1. J.Biol.Chem. 2020.
Page generated: Tue Jul 15 20:51:43 2025
ISSN: ESSN 1083-351X PubMed: 33361107 DOI: 10.1074/JBC.RA120.016573 |
Last articlesFe in 2YXOFe in 2YRS Fe in 2YXC Fe in 2YNM Fe in 2YVJ Fe in 2YP1 Fe in 2YU2 Fe in 2YU1 Fe in 2YQB Fe in 2YOO |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |