Fluorine in PDB 7m0t: Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Selumetinib

Enzymatic activity of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Selumetinib

Protein crystallography data

Other elements in 7m0t:

Fluorine Binding Sites:

Fluorine binding site 1 out of 1 in 7m0t

Fluorine Binding Sites List in 7m0t

Fluorine binding site 1 out of 1 in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Selumetinib


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Selumetinib within 5.0Å range: probe atom residue distance (Å) B Occ B:F401 b:108.2 occ:0.84 F1 B:3EW401 0.0 108.2 0.8 C4 B:3EW401 1.4 112.2 0.8 C3 B:3EW401 2.3 113.2 0.8 C5 B:3EW401 2.4 107.5 0.8 C9 B:3EW401 2.8 102.3 0.8 N1 B:3EW401 2.9 97.1 0.8 N4 B:3EW401 2.9 110.9 0.8 CG1 B:VAL211 3.1 108.0 1.0 C8 B:3EW401 3.1 98.5 0.8 O B:PHE209 3.4 118.4 1.0 CD2 B:LEU115 3.4 88.3 1.0 C2 B:3EW401 3.6 113.1 0.8 C6 B:3EW401 3.7 112.1 0.8 C10 B:3EW401 3.9 105.9 0.8 C1 B:3EW401 4.1 114.7 0.8 C14 B:3EW401 4.2 111.1 0.8 CD1 B:LEU118 4.2 93.8 1.0 N B:VAL211 4.3 110.3 1.0 N B:SER212 4.4 115.5 1.0 C B:PHE209 4.5 118.0 1.0 CB B:VAL211 4.5 110.0 1.0 C13 B:3EW401 4.5 101.1 0.8 N3 B:3EW401 4.5 108.3 0.8 CD2 B:LEU215 4.6 103.6 1.0 CB B:SER212 4.7 105.2 1.0 CG B:LEU115 4.8 81.6 1.0 CA B:VAL211 4.8 111.3 1.0 N B:PHE209 4.9 106.1 1.0 CD1 B:ILE141 5.0 87.9 1.0

Reference: