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Fluorine in PDB 7m0y: Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Trametinib
Enzymatic activity of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Trametinib
All present enzymatic activity of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Trametinib:
2.7.11.1; 2.7.12.2;
2.7.11.1; 2.7.12.2;
Protein crystallography data
The structure of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Trametinib, PDB code: 7m0y
was solved by
K.Li,
G.Gonzalez Del-Pino,
B.H.Ha,
E.Park,
M.J.Eck,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 47.08 / 3.45 |
| Space group | P 31 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 116.716, 116.716, 129.483, 90, 90, 120 |
| R / Rfree (%) | 19.5 / 21.8 |
Other elements in 7m0y:
The structure of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Trametinib also contains other interesting chemical elements:
| Iodine | (I) | 1 atom |
| Magnesium | (Mg) | 2 atoms |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Trametinib
(pdb code 7m0y). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Trametinib, PDB code: 7m0y:
In total only one binding site of Fluorine was determined in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Trametinib, PDB code: 7m0y:
Fluorine binding site 1 out of 1 in 7m0y
Go back to
Fluorine Binding Sites List in 7m0y
Fluorine binding site 1 out
of 1 in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Trametinib
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Trametinib within 5.0Å range:
|
Reference:
K.Li,
G.Gonzalez Del-Pino,
B.H.Ha,
E.Park,
M.J.Eck.
Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and Binimetinib To Be Published.
Page generated: Tue Jul 15 21:29:52 2025
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