Fluorine in PDB 7m0z: Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766

Enzymatic activity of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766

All present enzymatic activity of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766:
2.7.11.1; 2.7.12.2;

Protein crystallography data

The structure of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766, PDB code: 7m0z was solved by K.Li, G.Gonzalez Del-Pino, B.H.Ha, E.Park, M.J.Eck, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	43.33 / 3.12
*Space group*	P 3₁ 2 1
*Cell size a, b, c (Å), α, β, γ (°)*	116.784, 116.784, 129.256, 90, 90, 120
*R / R_free (%)*	19.1 / 22.5

Other elements in 7m0z:

The structure of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766 also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766 (pdb code 7m0z). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766, PDB code: 7m0z:

Fluorine binding site 1 out of 1 in 7m0z

Go back to

Fluorine Binding Sites List in 7m0z

Fluorine binding site 1 out of 1 in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766

Mono view

Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766 within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
B:F402 b:82.0 occ:1.00	F33	B:CHU402	0.0	82.0	1.0
	C22	B:CHU402	1.3	77.7	1.0
	C23	B:CHU402	2.3	82.8	1.0
	C14	B:CHU402	2.4	74.1	1.0
	N27	B:CHU402	2.7	91.4	1.0
	C13	B:CHU402	2.8	70.5	1.0
	CA	B:ILE216	3.1	77.5	1.0
	CB	B:MET219	3.4	71.0	1.0
	O	B:ILE216	3.6	75.8	1.0
	N24	B:CHU402	3.6	79.3	1.0
	C26	B:CHU402	3.7	81.5	1.0
	CB	B:ILE216	3.7	74.9	1.0
	CG2	B:ILE216	3.8	80.9	1.0
	C	B:ILE216	3.8	76.7	1.0
	CG1	B:ILE216	3.8	72.3	1.0
	O	B:LEU215	3.8	75.3	1.0
	CE	B:MET219	3.9	74.5	1.0
	N	B:ILE216	4.0	77.3	1.0
	C25	B:CHU402	4.1	77.3	1.0
	CG	B:MET219	4.1	88.0	1.0
	C	B:LEU215	4.2	73.9	1.0
	C8	B:CHU402	4.3	74.3	1.0
	S28	B:CHU402	4.3	87.1	1.0
	CA	B:MET219	4.7	76.7	1.0
	C12	B:CHU402	4.7	76.6	1.0
	O32	B:CHU402	4.7	74.8	1.0
	SD	B:MET219	4.9	96.3	1.0
	N	B:MET219	5.0	81.7	1.0

Reference:

K.Li, G.Gonzalez Del-Pino, B.H.Ha, E.Park, M.J.Eck. Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766 To Be Published.

Page generated: Tue Jul 15 21:29:52 2025

Last articles

Mg in 3CCE
Mg in 3CC7
Mg in 3CC4
Mg in 3CB3
Mg in 3CC6
Mg in 3C9U
Mg in 3CBT
Mg in 3CBQ
Mg in 3CBG
Mg in 3CBE

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy