Fluorine in PDB 7mge: Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1

The structure of Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1 also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Fluorine atom in the Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1 (pdb code 7mge). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1, PDB code: 7mge:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1 within 5.0Å range: probe atom residue distance (Å) B Occ E:F201 b:130.9 occ:1.00 F1 E:BEF201 0.0 130.9 1.0 BE E:BEF201 1.5 130.9 1.0 O E:VAL68 2.1 133.4 1.0 OG1 E:THR48 2.3 123.5 1.0 F3 E:BEF201 2.5 130.9 1.0 F2 E:BEF201 2.6 130.9 1.0 OD1 E:ASP67 2.8 136.1 1.0 CE E:LYS30 3.1 139.8 1.0 OD2 E:ASP67 3.2 136.1 1.0 C E:VAL68 3.3 133.4 1.0 OG1 E:THR31 3.3 143.5 1.0 CG E:ASP67 3.4 136.1 1.0 NZ E:LYS30 3.4 139.8 1.0 MG E:MG202 3.6 140.0 1.0 CB E:THR48 3.7 123.5 1.0 CA E:GLY69 3.9 141.0 1.0 O1B E:GDP200 4.0 146.3 1.0 N E:GLY69 4.0 141.0 1.0 O2B E:GDP200 4.1 146.3 1.0 N E:THR48 4.3 123.5 1.0 N E:VAL68 4.3 133.4 1.0 CG2 E:THR48 4.3 123.5 1.0 CA E:VAL68 4.4 133.4 1.0 CD E:LYS30 4.5 139.8 1.0 O E:THR48 4.5 123.5 1.0 CA E:THR48 4.5 123.5 1.0 CG E:LYS30 4.6 139.8 1.0 PB E:GDP200 4.7 146.3 1.0 CB E:THR31 4.7 143.5 1.0 CB E:ASP67 4.9 136.1 1.0 C E:THR48 4.9 123.5 1.0 C E:ASP67 4.9 136.1 1.0 C E:GLY69 5.0 141.0 1.0

Fluorine binding site 2 out of 3 in the Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1 within 5.0Å range: probe atom residue distance (Å) B Occ E:F201 b:130.9 occ:1.00 F2 E:BEF201 0.0 130.9 1.0 BE E:BEF201 1.6 130.9 1.0 MG E:MG202 1.9 140.0 1.0 OG1 E:THR31 2.1 143.5 1.0 O1B E:GDP200 2.3 146.3 1.0 F3 E:BEF201 2.5 130.9 1.0 F1 E:BEF201 2.6 130.9 1.0 PB E:GDP200 3.2 146.3 1.0 O2A E:GDP200 3.2 146.3 1.0 CB E:THR31 3.3 143.5 1.0 O3A E:GDP200 3.3 146.3 1.0 O2B E:GDP200 3.5 146.3 1.0 OG1 E:THR48 3.6 123.5 1.0 PA E:GDP200 3.6 146.3 1.0 NZ E:LYS30 3.7 139.8 1.0 O1A E:GDP200 3.8 146.3 1.0 OD1 E:ASP67 4.1 136.1 1.0 N E:THR48 4.2 123.5 1.0 N E:THR31 4.2 143.5 1.0 CE E:LYS30 4.2 139.8 1.0 CG2 E:THR31 4.2 143.5 1.0 CA E:THR31 4.3 143.5 1.0 OD2 E:ASP67 4.5 136.1 1.0 O3B E:GDP200 4.5 146.3 1.0 CG2 E:THR48 4.5 123.5 1.0 CB E:THR48 4.6 123.5 1.0 CG E:LYS30 4.6 139.8 1.0 O E:VAL68 4.7 133.4 1.0 CA E:PRO47 4.7 117.4 1.0 CG E:ASP67 4.7 136.1 1.0 C E:PRO47 5.0 117.4 1.0 O E:ILE46 5.0 127.5 1.0

Fluorine binding site 3 out of 3 in the Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1 within 5.0Å range: probe atom residue distance (Å) B Occ E:F201 b:130.9 occ:1.00 F3 E:BEF201 0.0 130.9 1.0 BE E:BEF201 1.5 130.9 1.0 MG E:MG202 1.8 140.0 1.0 NZ E:LYS30 2.2 139.8 1.0 O2B E:GDP200 2.4 146.3 1.0 F2 E:BEF201 2.5 130.9 1.0 F1 E:BEF201 2.5 130.9 1.0 CE E:LYS30 3.1 139.8 1.0 PB E:GDP200 3.2 146.3 1.0 O1B E:GDP200 3.3 146.3 1.0 O3A E:GDP200 3.4 146.3 1.0 O E:VAL68 4.0 133.4 1.0 OG1 E:THR48 4.2 123.5 1.0 OG1 E:THR31 4.3 143.5 1.0 N E:GLY70 4.4 144.4 1.0 CD E:LYS30 4.4 139.8 1.0 CA E:GLY69 4.5 141.0 1.0 PA E:GDP200 4.5 146.3 1.0 CG E:LYS30 4.6 139.8 1.0 O3B E:GDP200 4.6 146.3 1.0 O1A E:GDP200 4.7 146.3 1.0 OE1 E:GLN71 4.7 138.5 1.0 N E:THR48 4.8 123.5 1.0 O2A E:GDP200 4.8 146.3 1.0 OD1 E:ASP67 4.9 136.1 1.0 C E:GLY69 4.9 141.0 1.0 N E:ALA27 4.9 144.9 1.0 O E:LEU25 5.0 150.9 1.0 C E:VAL68 5.0 133.4 1.0

M.-Y.Su, S.A.Fromm, J.H.Hurley. Structural Basis For the Arf Gap Activity and Specificity of the C9ORF72 Complex To Be Published.