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Atomistry » Fluorine » PDB 7m8o-7mmh » 7mm9 » |
Fluorine in PDB 7mm9: Crystal Structure of Hcv NS3/4A Protease in Complex with NR01-149Protein crystallography data
The structure of Crystal Structure of Hcv NS3/4A Protease in Complex with NR01-149, PDB code: 7mm9
was solved by
J.Zephyr,
C.A.Schiffer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7mm9:
The structure of Crystal Structure of Hcv NS3/4A Protease in Complex with NR01-149 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Hcv NS3/4A Protease in Complex with NR01-149
(pdb code 7mm9). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Hcv NS3/4A Protease in Complex with NR01-149, PDB code: 7mm9: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 7mm9Go back to![]() ![]()
Fluorine binding site 1 out
of 2 in the Crystal Structure of Hcv NS3/4A Protease in Complex with NR01-149
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 2 in 7mm9Go back to![]() ![]()
Fluorine binding site 2 out
of 2 in the Crystal Structure of Hcv NS3/4A Protease in Complex with NR01-149
![]() Mono view ![]() Stereo pair view
Reference:
J.Zephyr,
D.Nageswara Rao,
S.V.Vo,
M.Henes,
K.Kosovrasti,
A.N.Matthew,
A.K.Hedger,
J.Timm,
E.T.Chan,
A.Ali,
N.Kurt Yilmaz,
C.A.Schiffer.
Deciphering the Molecular Mechanism of Hcv Protease Inhibitor Fluorination As A General Approach to Avoid Drug Resistance. J.Mol.Biol. V. 434 67503 2022.
Page generated: Tue Jul 15 21:46:43 2025
ISSN: ESSN 1089-8638 PubMed: 35183560 DOI: 10.1016/J.JMB.2022.167503 |
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