Fluorine in PDB 7mxy: Cryo-Em Structure of Pffnt-Inhibitor Complex

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>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 25;

Binding sites:

The binding sites of Fluorine atom in the Cryo-Em Structure of Pffnt-Inhibitor Complex (pdb code 7mxy). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 25 binding sites of Fluorine where determined in the Cryo-Em Structure of Pffnt-Inhibitor Complex, PDB code: 7mxy:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 25 in the Cryo-Em Structure of Pffnt-Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryo-Em Structure of Pffnt-Inhibitor Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:F1001 b:36.9 occ:1.00 F16 A:HV61001 0.0 36.9 1.0 C15 A:HV61001 1.4 36.9 1.0 F18 A:HV61001 2.2 36.9 1.0 F17 A:HV61001 2.2 36.9 1.0 C14 A:HV61001 2.3 36.9 1.0 HB3 A:ALA93 2.5 36.4 1.0 HE1 A:PHE90 2.5 35.2 1.0 F19 A:HV61001 2.6 36.9 1.0 F20 A:HV61001 2.7 36.9 1.0 CE1 A:PHE90 3.1 35.2 1.0 HG11 A:VAL220 3.3 35.6 1.0 CB A:ALA93 3.4 36.4 1.0 HB1 A:ALA93 3.6 36.4 1.0 C12 A:HV61001 3.6 36.9 1.0 H A:PHE94 3.7 37.1 1.0 HZ A:PHE90 3.7 35.2 1.0 CZ A:PHE90 3.7 35.2 1.0 HG13 A:VAL220 3.8 35.6 1.0 CD1 A:PHE90 3.8 35.2 1.0 HB2 A:ALA93 3.9 36.4 1.0 HD1 A:PHE90 3.9 35.2 1.0 HB2 A:PHE94 4.0 37.1 1.0 N A:PHE94 4.0 37.1 1.0 CG1 A:VAL220 4.0 35.6 1.0 HE2 A:PHE223 4.2 35.0 1.0 HD2 A:HIS230 4.3 34.5 1.0 H7 A:HV61001 4.3 36.9 1.0 HG22 A:VAL54 4.3 35.1 1.0 H A:ALA93 4.3 36.4 1.0 CA A:ALA93 4.3 36.4 1.0 C A:ALA93 4.4 36.4 1.0 HG21 A:VAL220 4.4 35.6 1.0 O21 A:HV61001 4.4 36.9 1.0 HE2 A:HIS230 4.4 34.5 1.0 C11 A:HV61001 4.4 36.9 1.0 H9 A:HV61001 4.4 36.9 1.0 HG22 A:VAL220 4.5 35.6 1.0 HA A:PRO91 4.5 36.1 1.0 HA A:PHE94 4.6 37.1 1.0 HG12 A:VAL220 4.6 35.6 1.0 HD11 A:ILE97 4.6 36.7 1.0 HG13 A:VAL54 4.7 35.1 1.0 CA A:PHE94 4.7 37.1 1.0 N A:ALA93 4.7 36.4 1.0 CB A:PHE94 4.8 37.1 1.0 CD2 A:HIS230 4.8 34.5 1.0 CG2 A:VAL220 4.8 35.6 1.0 HD11 A:LEU104 4.8 35.5 1.0 O A:PHE90 4.9 35.2 1.0 NE2 A:HIS230 4.9 34.5 1.0 HD2 A:PHE94 4.9 37.1 1.0 CE2 A:PHE90 4.9 35.2 1.0 HD12 A:LEU104 4.9 35.5 1.0 CG A:PHE90 5.0 35.2 1.0

Fluorine binding site 2 out of 25 in the Cryo-Em Structure of Pffnt-Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Cryo-Em Structure of Pffnt-Inhibitor Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:F1001 b:36.9 occ:1.00 F17 A:HV61001 0.0 36.9 1.0 C15 A:HV61001 1.4 36.9 1.0 F18 A:HV61001 2.2 36.9 1.0 F16 A:HV61001 2.2 36.9 1.0 C14 A:HV61001 2.4 36.9 1.0 F20 A:HV61001 2.7 36.9 1.0 HE2 A:HIS230 2.7 34.5 1.0 HD11 A:LEU104 2.9 35.5 1.0 C12 A:HV61001 2.9 36.9 1.0 HG22 A:VAL54 2.9 35.1 1.0 O21 A:HV61001 3.1 36.9 1.0 NE2 A:HIS230 3.2 34.5 1.0 HD13 A:LEU104 3.2 35.5 1.0 HD12 A:LEU104 3.3 35.5 1.0 CD1 A:LEU104 3.3 35.5 1.0 H9 A:HV61001 3.4 36.9 1.0 F19 A:HV61001 3.5 36.9 1.0 HD2 A:HIS230 3.6 34.5 1.0 HE1 A:PHE90 3.6 35.2 1.0 CD2 A:HIS230 3.7 34.5 1.0 HB3 A:ALA93 3.7 36.4 1.0 C11 A:HV61001 3.8 36.9 1.0 CG2 A:VAL54 3.8 35.1 1.0 HG13 A:VAL54 3.9 35.1 1.0 HZ A:PHE90 3.9 35.2 1.0 HB1 A:ALA93 3.9 36.4 1.0 HG11 A:VAL54 4.0 35.1 1.0 HG21 A:VAL54 4.0 35.1 1.0 H7 A:HV61001 4.1 36.9 1.0 HD11 A:ILE97 4.1 36.7 1.0 HD13 A:ILE97 4.1 36.7 1.0 CE1 A:HIS230 4.2 34.5 1.0 CE1 A:PHE90 4.3 35.2 1.0 CB A:ALA93 4.3 36.4 1.0 CG1 A:VAL54 4.3 35.1 1.0 HD12 A:ILE97 4.4 36.7 1.0 HG23 A:VAL54 4.4 35.1 1.0 CZ A:PHE90 4.4 35.2 1.0 CD1 A:ILE97 4.4 36.7 1.0 HE1 A:HIS230 4.5 34.5 1.0 HG1 A:THR106 4.7 35.3 1.0 CB A:VAL54 4.7 35.1 1.0 CG A:LEU104 4.8 35.5 1.0 CG A:HIS230 4.8 34.5 1.0 HB A:ILE232 4.8 34.3 1.0 HD21 A:LEU104 4.8 35.5 1.0 HB2 A:ALA93 4.8 36.4 1.0 HA A:VAL54 4.9 35.1 1.0 C09 A:HV61001 4.9 36.9 1.0 ND1 A:HIS230 5.0 34.5 1.0

Fluorine binding site 3 out of 25 in the Cryo-Em Structure of Pffnt-Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Cryo-Em Structure of Pffnt-Inhibitor Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:F1001 b:36.9 occ:1.00 F18 A:HV61001 0.0 36.9 1.0 C15 A:HV61001 1.4 36.9 1.0 F16 A:HV61001 2.2 36.9 1.0 F17 A:HV61001 2.2 36.9 1.0 C14 A:HV61001 2.3 36.9 1.0 HD11 A:ILE97 2.5 36.7 1.0 HB3 A:ALA93 2.7 36.4 1.0 H7 A:HV61001 2.8 36.9 1.0 F19 A:HV61001 2.8 36.9 1.0 C12 A:HV61001 2.8 36.9 1.0 HA A:PHE94 2.9 37.1 1.0 HB1 A:ALA93 3.0 36.4 1.0 C11 A:HV61001 3.1 36.9 1.0 N A:PHE94 3.1 37.1 1.0 CD1 A:ILE97 3.2 36.7 1.0 HD12 A:LEU104 3.2 35.5 1.0 CB A:ALA93 3.3 36.4 1.0 C A:ALA93 3.3 36.4 1.0 H A:PHE94 3.3 37.1 1.0 HD12 A:ILE97 3.3 36.7 1.0 HD13 A:ILE97 3.4 36.7 1.0 HD11 A:LEU104 3.4 35.5 1.0 CA A:PHE94 3.4 37.1 1.0 F20 A:HV61001 3.5 36.9 1.0 HB2 A:PHE94 3.5 37.1 1.0 HG22 A:VAL54 3.6 35.1 1.0 O A:ALA93 3.6 36.4 1.0 CD1 A:LEU104 3.8 35.5 1.0 CA A:ALA93 3.9 36.4 1.0 O21 A:HV61001 3.9 36.9 1.0 CB A:PHE94 4.0 37.1 1.0 HB2 A:ALA93 4.1 36.4 1.0 HD13 A:LEU104 4.1 35.5 1.0 H9 A:HV61001 4.3 36.9 1.0 HD2 A:PHE94 4.4 37.1 1.0 C09 A:HV61001 4.4 36.9 1.0 CG2 A:VAL54 4.5 35.1 1.0 HE2 A:HIS230 4.5 34.5 1.0 HB A:ILE97 4.5 36.7 1.0 CG1 A:ILE97 4.6 36.7 1.0 HG23 A:VAL54 4.6 35.1 1.0 HA A:ALA93 4.6 36.4 1.0 HE1 A:PHE90 4.6 35.2 1.0 CG A:PHE94 4.7 37.1 1.0 HG13 A:ILE97 4.7 36.7 1.0 H5 A:HV61001 4.7 36.9 1.0 N A:ALA93 4.8 36.4 1.0 HB3 A:PHE94 4.8 37.1 1.0 H A:ALA93 4.8 36.4 1.0 C A:PHE94 4.8 37.1 1.0 CD2 A:PHE94 4.8 37.1 1.0 HG21 A:VAL54 4.9 35.1 1.0

Fluorine binding site 4 out of 25 in the Cryo-Em Structure of Pffnt-Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Cryo-Em Structure of Pffnt-Inhibitor Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:F1001 b:36.9 occ:1.00 F19 A:HV61001 0.0 36.9 1.0 C14 A:HV61001 1.4 36.9 1.0 F20 A:HV61001 2.2 36.9 1.0 C15 A:HV61001 2.3 36.9 1.0 C12 A:HV61001 2.4 36.9 1.0 HD2 A:PHE94 2.4 37.1 1.0 HB2 A:PHE94 2.6 37.1 1.0 F16 A:HV61001 2.6 36.9 1.0 H7 A:HV61001 2.7 36.9 1.0 F18 A:HV61001 2.8 36.9 1.0 HG22 A:VAL220 2.9 35.6 1.0 C11 A:HV61001 2.9 36.9 1.0 HG21 A:VAL220 3.1 35.6 1.0 CD2 A:PHE94 3.3 37.1 1.0 H9 A:HV61001 3.4 36.9 1.0 CB A:PHE94 3.4 37.1 1.0 CG2 A:VAL220 3.4 35.6 1.0 O21 A:HV61001 3.5 36.9 1.0 F17 A:HV61001 3.5 36.9 1.0 HG11 A:VAL220 3.7 35.6 1.0 HG13 A:VAL220 3.7 35.6 1.0 CG A:PHE94 3.8 37.1 1.0 HG22 A:VAL196 3.8 36.2 1.0 HA A:PHE94 3.8 37.1 1.0 H A:PHE94 3.9 37.1 1.0 CA A:PHE94 4.0 37.1 1.0 CG1 A:VAL220 4.1 35.6 1.0 HG23 A:VAL220 4.1 35.6 1.0 N A:PHE94 4.1 37.1 1.0 HB3 A:PHE94 4.1 37.1 1.0 CE2 A:PHE94 4.3 37.1 1.0 HB3 A:ALA93 4.4 36.4 1.0 CB A:VAL220 4.4 35.6 1.0 C09 A:HV61001 4.4 36.9 1.0 HE2 A:PHE94 4.4 37.1 1.0 HE1 A:PHE90 4.5 35.2 1.0 HG13 A:VAL216 4.6 37.2 1.0 H5 A:HV61001 4.6 36.9 1.0 HE2 A:HIS230 4.7 34.5 1.0 CG2 A:VAL196 4.7 36.2 1.0 HG13 A:VAL196 4.7 36.2 1.0 HD2 A:HIS230 4.8 34.5 1.0 HD12 A:LEU104 4.8 35.5 1.0 HE2 A:PHE223 4.9 35.0 1.0 HG21 A:VAL196 4.9 36.2 1.0 HG12 A:VAL220 5.0 35.6 1.0

Fluorine binding site 5 out of 25 in the Cryo-Em Structure of Pffnt-Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Cryo-Em Structure of Pffnt-Inhibitor Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:F1001 b:36.9 occ:1.00 F20 A:HV61001 0.0 36.9 1.0 C14 A:HV61001 1.4 36.9 1.0 H9 A:HV61001 2.1 36.9 1.0 F19 A:HV61001 2.2 36.9 1.0 C15 A:HV61001 2.3 36.9 1.0 C12 A:HV61001 2.3 36.9 1.0 O21 A:HV61001 2.5 36.9 1.0 F17 A:HV61001 2.7 36.9 1.0 HD2 A:HIS230 2.7 34.5 1.0 F16 A:HV61001 2.7 36.9 1.0 HG22 A:VAL196 2.7 36.2 1.0 HE2 A:HIS230 2.9 34.5 1.0 CD2 A:HIS230 3.2 34.5 1.0 HG21 A:VAL196 3.3 36.2 1.0 NE2 A:HIS230 3.3 34.5 1.0 CG2 A:VAL196 3.4 36.2 1.0 F18 A:HV61001 3.5 36.9 1.0 C11 A:HV61001 3.6 36.9 1.0 HG13 A:VAL220 3.7 35.6 1.0 HE1 A:PHE90 3.7 35.2 1.0 HE2 A:PHE223 3.8 35.0 1.0 HG22 A:VAL220 3.8 35.6 1.0 H7 A:HV61001 3.9 36.9 1.0 HG23 A:VAL196 3.9 36.2 1.0 HG11 A:VAL220 4.2 35.6 1.0 CE2 A:PHE223 4.2 35.0 1.0 HG11 A:VAL196 4.3 36.2 1.0 HD2 A:PHE94 4.3 37.1 1.0 HG13 A:VAL196 4.4 36.2 1.0 HG1 A:THR106 4.4 35.3 1.0 CG1 A:VAL220 4.4 35.6 1.0 CB A:VAL196 4.6 36.2 1.0 HD13 A:LEU104 4.6 35.5 1.0 CG A:HIS230 4.6 34.5 1.0 CG1 A:VAL196 4.6 36.2 1.0 CE1 A:PHE90 4.6 35.2 1.0 HD12 A:LEU104 4.6 35.5 1.0 CG2 A:VAL220 4.6 35.6 1.0 CE1 A:HIS230 4.7 34.5 1.0 HG21 A:VAL220 4.7 35.6 1.0 HB2 A:PHE94 4.7 37.1 1.0 HA A:VAL196 4.8 36.2 1.0 C09 A:HV61001 4.8 36.9 1.0 HZ A:PHE223 4.8 35.0 1.0 HD2 A:PHE223 4.8 35.0 1.0 CZ A:PHE223 4.8 35.0 1.0 CD2 A:PHE223 4.8 35.0 1.0 O10 A:HV61001 4.9 36.9 1.0 CD1 A:LEU104 5.0 35.5 1.0 HD11 A:LEU104 5.0 35.5 1.0

Fluorine binding site 6 out of 25 in the Cryo-Em Structure of Pffnt-Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Cryo-Em Structure of Pffnt-Inhibitor Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:F401 b:36.9 occ:1.00 F16 B:HV6401 0.0 36.9 1.0 C15 B:HV6401 1.4 36.9 1.0 F17 B:HV6401 2.2 36.9 1.0 F18 B:HV6401 2.2 36.9 1.0 C14 B:HV6401 2.4 36.9 1.0 HD12 B:ILE97 2.5 37.1 1.0 C12 B:HV6401 2.8 36.9 1.0 H7 B:HV6401 2.8 36.9 1.0 F20 B:HV6401 2.8 36.9 1.0 C11 B:HV6401 3.0 36.9 1.0 HB3 B:ALA93 3.0 36.8 1.0 HB1 B:ALA93 3.0 36.8 1.0 HG22 B:VAL54 3.0 35.7 1.0 HD11 B:ILE97 3.0 37.1 1.0 CD1 B:ILE97 3.1 37.1 1.0 HD13 B:ILE97 3.2 37.1 1.0 HD22 B:LEU104 3.3 35.7 1.0 CB B:ALA93 3.4 36.8 1.0 HA B:PHE94 3.5 37.1 1.0 F19 B:HV6401 3.5 36.9 1.0 C B:ALA93 3.7 36.8 1.0 N B:PHE94 3.7 37.1 1.0 O21 B:HV6401 3.8 36.9 1.0 CG2 B:VAL54 3.9 35.7 1.0 O B:ALA93 3.9 36.8 1.0 H B:PHE94 4.0 37.1 1.0 CA B:PHE94 4.1 37.1 1.0 HG21 B:VAL54 4.1 35.7 1.0 HG23 B:VAL54 4.1 35.7 1.0 CD2 B:LEU104 4.2 35.7 1.0 CA B:ALA93 4.2 36.8 1.0 C09 B:HV6401 4.2 36.9 1.0 H9 B:HV6401 4.2 36.9 1.0 HB2 B:ALA93 4.2 36.8 1.0 HD2 B:PHE94 4.3 37.1 1.0 HD21 B:LEU104 4.4 35.7 1.0 H5 B:HV6401 4.4 36.9 1.0 CG1 B:ILE97 4.4 37.1 1.0 HB2 B:PHE94 4.4 37.1 1.0 HD23 B:LEU104 4.6 35.7 1.0 HB B:ILE97 4.6 37.1 1.0 HE2 B:PHE90 4.6 36.0 1.0 HG13 B:ILE97 4.6 37.1 1.0 CB B:PHE94 4.7 37.1 1.0 HD13 B:LEU104 4.8 35.7 1.0 O10 B:HV6401 4.8 36.9 1.0 CD2 B:PHE94 4.8 37.1 1.0 HA B:ALA93 4.8 36.8 1.0 HA B:VAL54 4.9 35.7 1.0 HB2 B:LEU104 5.0 35.7 1.0

Fluorine binding site 7 out of 25 in the Cryo-Em Structure of Pffnt-Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Cryo-Em Structure of Pffnt-Inhibitor Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:F401 b:36.9 occ:1.00 F17 B:HV6401 0.0 36.9 1.0 C15 B:HV6401 1.4 36.9 1.0 F16 B:HV6401 2.2 36.9 1.0 F18 B:HV6401 2.2 36.9 1.0 C14 B:HV6401 2.3 36.9 1.0 HE2 B:PHE90 2.5 36.0 1.0 HB3 B:ALA93 2.6 36.8 1.0 F20 B:HV6401 2.6 36.9 1.0 F19 B:HV6401 2.8 36.9 1.0 CE2 B:PHE90 3.0 36.0 1.0 CB B:ALA93 3.4 36.8 1.0 HB1 B:ALA93 3.5 36.8 1.0 HG11 B:VAL220 3.5 36.2 1.0 HZ B:PHE90 3.6 36.0 1.0 CZ B:PHE90 3.6 36.0 1.0 C12 B:HV6401 3.7 36.9 1.0 CD2 B:PHE90 3.8 36.0 1.0 HG22 B:VAL54 3.8 35.7 1.0 HD2 B:PHE90 3.9 36.0 1.0 HB2 B:ALA93 3.9 36.8 1.0 HG21 B:VAL220 4.1 36.2 1.0 H B:PHE94 4.1 37.1 1.0 H7 B:HV6401 4.2 36.9 1.0 N B:PHE94 4.3 37.1 1.0 HG22 B:VAL220 4.3 36.2 1.0 C11 B:HV6401 4.4 36.9 1.0 CG1 B:VAL220 4.4 36.2 1.0 HG13 B:VAL220 4.4 36.2 1.0 CA B:ALA93 4.5 36.8 1.0 C B:ALA93 4.5 36.8 1.0 HD12 B:ILE97 4.6 37.1 1.0 O21 B:HV6401 4.6 36.9 1.0 HG13 B:VAL54 4.6 35.7 1.0 HB2 B:PHE94 4.6 37.1 1.0 H B:ALA93 4.6 36.8 1.0 HD2 B:PHE94 4.6 37.1 1.0 H9 B:HV6401 4.6 36.9 1.0 CG2 B:VAL220 4.6 36.2 1.0 CE1 B:PHE90 4.7 36.0 1.0 HA B:PRO91 4.7 36.3 1.0 HA B:PHE94 4.8 37.1 1.0 CG2 B:VAL54 4.8 35.7 1.0 HD22 B:LEU104 4.8 35.7 1.0 CG B:PHE90 4.8 36.0 1.0 NE2 B:HIS230 4.9 34.7 1.0 HE2 B:PHE223 4.9 35.3 1.0 HG11 B:VAL54 4.9 35.7 1.0 O B:PHE90 4.9 36.0 1.0 N B:ALA93 4.9 36.8 1.0 HD11 B:ILE97 5.0 37.1 1.0

Fluorine binding site 8 out of 25 in the Cryo-Em Structure of Pffnt-Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Cryo-Em Structure of Pffnt-Inhibitor Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:F401 b:36.9 occ:1.00 F18 B:HV6401 0.0 36.9 1.0 C15 B:HV6401 1.4 36.9 1.0 F16 B:HV6401 2.2 36.9 1.0 F17 B:HV6401 2.2 36.9 1.0 C14 B:HV6401 2.4 36.9 1.0 F19 B:HV6401 2.7 36.9 1.0 HG22 B:VAL54 2.7 35.7 1.0 HD22 B:LEU104 2.9 35.7 1.0 C12 B:HV6401 2.9 36.9 1.0 HD21 B:LEU104 3.1 35.7 1.0 O21 B:HV6401 3.2 36.9 1.0 CD2 B:LEU104 3.3 35.7 1.0 H9 B:HV6401 3.4 36.9 1.0 HG21 B:VAL54 3.4 35.7 1.0 NE2 B:HIS230 3.4 34.7 1.0 HE1 B:HIS230 3.4 34.7 1.0 HG11 B:VAL54 3.4 35.7 1.0 CG2 B:VAL54 3.4 35.7 1.0 HE2 B:PHE90 3.5 36.0 1.0 CE1 B:HIS230 3.5 34.7 1.0 F20 B:HV6401 3.5 36.9 1.0 HD23 B:LEU104 3.5 35.7 1.0 HZ B:PHE90 3.6 36.0 1.0 HG13 B:VAL54 3.8 35.7 1.0 C11 B:HV6401 3.9 36.9 1.0 CG1 B:VAL54 4.0 35.7 1.0 HB3 B:ALA93 4.0 36.8 1.0 CE2 B:PHE90 4.1 36.0 1.0 HB1 B:ALA93 4.1 36.8 1.0 HG23 B:VAL54 4.1 35.7 1.0 CZ B:PHE90 4.2 36.0 1.0 HD11 B:ILE97 4.2 37.1 1.0 H7 B:HV6401 4.2 36.9 1.0 CD2 B:HIS230 4.3 34.7 1.0 HD12 B:ILE97 4.3 37.1 1.0 CB B:VAL54 4.3 35.7 1.0 ND1 B:HIS230 4.4 34.7 1.0 HD13 B:ILE97 4.5 37.1 1.0 CB B:ALA93 4.5 36.8 1.0 CD1 B:ILE97 4.6 37.1 1.0 HB B:ILE232 4.7 34.5 1.0 HD2 B:HIS230 4.7 34.7 1.0 HA B:VAL54 4.8 35.7 1.0 CG B:LEU104 4.8 35.7 1.0 HD13 B:LEU104 4.8 35.7 1.0 CG B:HIS230 4.8 34.7 1.0 HB2 B:ALA233 4.8 34.4 1.0 HD1 B:HIS230 4.8 34.7 1.0 HG12 B:VAL54 4.9 35.7 1.0 C09 B:HV6401 5.0 36.9 1.0

Fluorine binding site 9 out of 25 in the Cryo-Em Structure of Pffnt-Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of Cryo-Em Structure of Pffnt-Inhibitor Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:F401 b:36.9 occ:1.00 F19 B:HV6401 0.0 36.9 1.0 C14 B:HV6401 1.4 36.9 1.0 F20 B:HV6401 2.2 36.9 1.0 C15 B:HV6401 2.4 36.9 1.0 C12 B:HV6401 2.4 36.9 1.0 H9 B:HV6401 2.4 36.9 1.0 F18 B:HV6401 2.7 36.9 1.0 HG22 B:VAL196 2.7 36.3 1.0 O21 B:HV6401 2.7 36.9 1.0 NE2 B:HIS230 2.8 34.7 1.0 F17 B:HV6401 2.8 36.9 1.0 HG21 B:VAL196 3.1 36.3 1.0 HD2 B:HIS230 3.1 34.7 1.0 CD2 B:HIS230 3.2 34.7 1.0 CG2 B:VAL196 3.3 36.3 1.0 F16 B:HV6401 3.5 36.9 1.0 C11 B:HV6401 3.5 36.9 1.0 HE2 B:PHE90 3.6 36.0 1.0 CE1 B:HIS230 3.8 34.7 1.0 HG22 B:VAL220 3.8 36.2 1.0 H7 B:HV6401 3.8 36.9 1.0 HG23 B:VAL196 3.9 36.3 1.0 HG11 B:VAL196 4.0 36.3 1.0 HE2 B:PHE223 4.1 35.3 1.0 HE1 B:HIS230 4.2 34.7 1.0 HG13 B:VAL196 4.3 36.3 1.0 HD2 B:PHE223 4.3 35.3 1.0 CG B:HIS230 4.3 34.7 1.0 HD2 B:PHE94 4.3 37.1 1.0 HD22 B:LEU104 4.4 35.7 1.0 CG1 B:VAL196 4.4 36.3 1.0 CB B:VAL196 4.5 36.3 1.0 HD23 B:LEU104 4.5 35.7 1.0 CE2 B:PHE90 4.5 36.0 1.0 HG21 B:VAL220 4.5 36.2 1.0 ND1 B:HIS230 4.6 34.7 1.0 HG11 B:VAL220 4.6 36.2 1.0 CE2 B:PHE223 4.6 35.3 1.0 CG2 B:VAL220 4.6 36.2 1.0 HG13 B:VAL220 4.6 36.2 1.0 CD2 B:PHE223 4.7 35.3 1.0 C09 B:HV6401 4.8 36.9 1.0 HA B:VAL196 4.8 36.3 1.0 CD2 B:LEU104 4.8 35.7 1.0 O10 B:HV6401 4.9 36.9 1.0 HD21 B:LEU104 5.0 35.7 1.0

Fluorine binding site 10 out of 25 in the Cryo-Em Structure of Pffnt-Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of Cryo-Em Structure of Pffnt-Inhibitor Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:F401 b:36.9 occ:1.00 F20 B:HV6401 0.0 36.9 1.0 C14 B:HV6401 1.4 36.9 1.0 F19 B:HV6401 2.2 36.9 1.0 HD2 B:PHE94 2.3 37.1 1.0 C15 B:HV6401 2.4 36.9 1.0 C12 B:HV6401 2.4 36.9 1.0 H7 B:HV6401 2.5 36.9 1.0 F17 B:HV6401 2.6 36.9 1.0 C11 B:HV6401 2.8 36.9 1.0 F16 B:HV6401 2.8 36.9 1.0 HG22 B:VAL220 2.9 36.2 1.0 HG21 B:VAL220 3.0 36.2 1.0 CD2 B:PHE94 3.1 37.1 1.0 CG2 B:VAL220 3.4 36.2 1.0 HB2 B:PHE94 3.4 37.1 1.0 F18 B:HV6401 3.5 36.9 1.0 HG22 B:VAL196 3.6 36.3 1.0 O21 B:HV6401 3.6 36.9 1.0 H9 B:HV6401 3.7 36.9 1.0 HE2 B:PHE94 3.8 37.1 1.0 HG23 B:VAL220 3.9 36.2 1.0 CE2 B:PHE94 3.9 37.1 1.0 HA B:PHE94 4.0 37.1 1.0 HG11 B:VAL220 4.0 36.2 1.0 CG B:PHE94 4.0 37.1 1.0 CB B:PHE94 4.1 37.1 1.0 C09 B:HV6401 4.2 36.9 1.0 H B:PHE94 4.3 37.1 1.0 HG13 B:VAL196 4.3 36.3 1.0 CA B:PHE94 4.4 37.1 1.0 H5 B:HV6401 4.4 36.9 1.0 N B:PHE94 4.4 37.1 1.0 HE2 B:PHE90 4.5 36.0 1.0 HB3 B:ALA93 4.5 36.8 1.0 CG2 B:VAL196 4.5 36.3 1.0 CG1 B:VAL220 4.6 36.2 1.0 HG13 B:VAL220 4.6 36.2 1.0 CB B:VAL220 4.6 36.2 1.0 HG21 B:VAL196 4.7 36.3 1.0 HD12 B:ILE97 4.8 37.1 1.0 HG11 B:VAL196 4.8 36.3 1.0 HA B:VAL196 4.8 36.3 1.0 NE2 B:HIS230 4.9 34.7 1.0 O10 B:HV6401 4.9 36.9 1.0 HB3 B:PHE94 4.9 37.1 1.0 CG1 B:VAL196 5.0 36.3 1.0 HD22 B:LEU104 5.0 35.7 1.0

M.Lyu, C.Su, J.W.Kazura, E.W.Yu. Structural Basis of Transport and Inhibition of the Plasmodium Falciparum Transporter Pffnt Embo Rep V. 22 51628 2021.
ISSN: ISSN 1469-221X
PubMed: 33471955
DOI: 10.15252/EMBR.202051628