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Atomistry » Fluorine » PDB 7qmw-7r9f » 7r53 » |
Fluorine in PDB 7r53: Crystal Structure of Human TLR8 in Complex with Compound 15Protein crystallography data
The structure of Crystal Structure of Human TLR8 in Complex with Compound 15, PDB code: 7r53
was solved by
M.Faller,
F.Zink,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human TLR8 in Complex with Compound 15
(pdb code 7r53). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Human TLR8 in Complex with Compound 15, PDB code: 7r53: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 7r53Go back to![]() ![]()
Fluorine binding site 1 out
of 2 in the Crystal Structure of Human TLR8 in Complex with Compound 15
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 2 in 7r53Go back to![]() ![]()
Fluorine binding site 2 out
of 2 in the Crystal Structure of Human TLR8 in Complex with Compound 15
![]() Mono view ![]() Stereo pair view
Reference:
C.Betschart,
M.Faller,
F.Zink,
R.Hemmig,
J.Blank,
E.Vangrevelinghe,
M.Bourrel,
R.Glatthar,
D.Behnke,
K.Barker,
A.Heizmann,
D.Angst,
P.Nimsgern,
S.Jacquier,
T.Junt,
G.Zipfel,
G.Ruzzante,
P.Loetscher,
S.Limonta,
S.Hawtin,
C.B.Andre,
T.Boulay,
R.Feifel,
T.Knoepfel.
Structure-Based Optimization of A Fragment-Like TLR8 Binding Screening Hit to An in Vivo Efficacious TLR7/8 Antagonist. Acs Med.Chem.Lett. V. 13 658 2022.
Page generated: Tue Jul 15 23:26:09 2025
ISSN: ISSN 1948-5875 PubMed: 35450354 DOI: 10.1021/ACSMEDCHEMLETT.1C00696 |
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