Fluorine in PDB 7rdx: Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class
Enzymatic activity of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class
All present enzymatic activity of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class:
2.7.7.48;
3.6.4.12;
3.6.4.13;
Other elements in 7rdx:
The structure of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class
(pdb code 7rdx). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the
Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class, PDB code: 7rdx:
Jump to Fluorine binding site number:
1;
2;
3;
4;
5;
6;
Fluorine binding site 1 out
of 6 in 7rdx
Go back to
Fluorine Binding Sites List in 7rdx
Fluorine binding site 1 out
of 6 in the Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:F706
b:115.0
occ:1.00
|
F1
|
E:AF3706
|
0.0
|
115.0
|
1.0
|
|
AL
|
E:AF3706
|
1.8
|
115.0
|
1.0
|
|
MG
|
E:MG705
|
2.0
|
108.5
|
1.0
|
|
O3B
|
E:ADP704
|
2.2
|
115.4
|
1.0
|
|
HH12
|
E:ARG443
|
2.4
|
130.5
|
1.0
|
|
HH22
|
E:ARG443
|
2.7
|
130.5
|
1.0
|
|
O1A
|
E:ADP704
|
2.8
|
115.4
|
1.0
|
|
NH1
|
E:ARG443
|
3.0
|
130.5
|
1.0
|
|
F2
|
E:AF3706
|
3.1
|
115.0
|
1.0
|
|
F3
|
E:AF3706
|
3.1
|
115.0
|
1.0
|
|
NH2
|
E:ARG443
|
3.2
|
130.5
|
1.0
|
|
PB
|
E:ADP704
|
3.3
|
115.4
|
1.0
|
|
CZ
|
E:ARG443
|
3.4
|
130.5
|
1.0
|
|
HA2
|
E:GLY538
|
3.4
|
123.4
|
1.0
|
|
O3A
|
E:ADP704
|
3.5
|
115.4
|
1.0
|
|
HH11
|
E:ARG443
|
3.6
|
130.5
|
1.0
|
|
HH21
|
E:ARG567
|
3.6
|
133.8
|
1.0
|
|
OG
|
E:SER289
|
3.6
|
104.9
|
1.0
|
|
PA
|
E:ADP704
|
3.7
|
115.4
|
1.0
|
|
H
|
E:GLY285
|
3.8
|
119.3
|
1.0
|
|
O
|
E:GLY538
|
3.8
|
123.4
|
1.0
|
|
NH2
|
E:ARG567
|
3.8
|
133.8
|
1.0
|
|
O2B
|
E:ADP704
|
3.8
|
115.4
|
1.0
|
|
HH21
|
E:ARG443
|
3.9
|
130.5
|
1.0
|
|
HH22
|
E:ARG567
|
4.0
|
133.8
|
1.0
|
|
HA2
|
E:GLY285
|
4.2
|
119.3
|
1.0
|
|
CA
|
E:GLY538
|
4.2
|
123.4
|
1.0
|
|
C
|
E:GLY538
|
4.3
|
123.4
|
1.0
|
|
H
|
E:GLY538
|
4.3
|
123.4
|
1.0
|
|
CZ
|
E:ARG567
|
4.4
|
133.8
|
1.0
|
|
HB2
|
E:SER289
|
4.4
|
104.9
|
1.0
|
|
HE
|
E:ARG567
|
4.5
|
133.8
|
1.0
|
|
N
|
E:GLY285
|
4.5
|
119.3
|
1.0
|
|
O1B
|
E:ADP704
|
4.6
|
115.4
|
1.0
|
|
NE
|
E:ARG443
|
4.6
|
130.5
|
1.0
|
|
CB
|
E:SER289
|
4.6
|
104.9
|
1.0
|
|
NE
|
E:ARG567
|
4.6
|
133.8
|
1.0
|
|
N
|
E:GLY538
|
4.7
|
123.4
|
1.0
|
|
O2A
|
E:ADP704
|
4.8
|
115.4
|
1.0
|
|
OE2
|
E:GLU375
|
4.8
|
96.7
|
1.0
|
|
O5'
|
E:ADP704
|
4.8
|
115.4
|
1.0
|
|
CA
|
E:GLY285
|
4.9
|
119.3
|
1.0
|
|
H
|
E:SER289
|
4.9
|
104.9
|
1.0
|
|
HA3
|
E:GLY538
|
5.0
|
123.4
|
1.0
|
|
HE2
|
E:LYS288
|
5.0
|
103.1
|
1.0
|
|
Fluorine binding site 2 out
of 6 in 7rdx
Go back to
Fluorine Binding Sites List in 7rdx
Fluorine binding site 2 out
of 6 in the Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:F706
b:115.0
occ:1.00
|
F2
|
E:AF3706
|
0.0
|
115.0
|
1.0
|
|
AL
|
E:AF3706
|
1.8
|
115.0
|
1.0
|
|
HE22
|
E:GLN404
|
2.2
|
113.5
|
1.0
|
|
O3B
|
E:ADP704
|
2.8
|
115.4
|
1.0
|
|
NE2
|
E:GLN404
|
3.0
|
113.5
|
1.0
|
|
F1
|
E:AF3706
|
3.1
|
115.0
|
1.0
|
|
F3
|
E:AF3706
|
3.1
|
115.0
|
1.0
|
|
HA
|
E:PRO284
|
3.2
|
119.0
|
1.0
|
|
HH22
|
E:ARG567
|
3.2
|
133.8
|
1.0
|
|
HZ1
|
E:LYS288
|
3.3
|
103.1
|
1.0
|
|
H
|
E:GLY285
|
3.4
|
119.3
|
1.0
|
|
MG
|
E:MG705
|
3.4
|
108.5
|
1.0
|
|
OE2
|
E:GLU375
|
3.5
|
96.7
|
1.0
|
|
OE1
|
E:GLN404
|
3.6
|
113.5
|
1.0
|
|
NH2
|
E:ARG567
|
3.6
|
133.8
|
1.0
|
|
HE21
|
E:GLN404
|
3.6
|
113.5
|
1.0
|
|
CD
|
E:GLN404
|
3.7
|
113.5
|
1.0
|
|
HB3
|
E:PRO284
|
3.8
|
119.0
|
1.0
|
|
HH12
|
E:ARG567
|
3.8
|
133.8
|
1.0
|
|
HE2
|
E:LYS288
|
3.8
|
103.1
|
1.0
|
|
HE3
|
E:LYS288
|
4.0
|
103.1
|
1.0
|
|
HH21
|
E:ARG567
|
4.0
|
133.8
|
1.0
|
|
CA
|
E:PRO284
|
4.0
|
119.0
|
1.0
|
|
NZ
|
E:LYS288
|
4.0
|
103.1
|
1.0
|
|
N
|
E:GLY285
|
4.1
|
119.3
|
1.0
|
|
CZ
|
E:ARG567
|
4.2
|
133.8
|
1.0
|
|
CE
|
E:LYS288
|
4.2
|
103.1
|
1.0
|
|
NH1
|
E:ARG567
|
4.2
|
133.8
|
1.0
|
|
PB
|
E:ADP704
|
4.2
|
115.4
|
1.0
|
|
CB
|
E:PRO284
|
4.2
|
119.0
|
1.0
|
|
HB2
|
E:PRO284
|
4.3
|
119.0
|
1.0
|
|
HZ2
|
E:LYS288
|
4.3
|
103.1
|
1.0
|
|
CD
|
E:GLU375
|
4.4
|
96.7
|
1.0
|
|
OE1
|
E:GLU375
|
4.5
|
96.7
|
1.0
|
|
HA2
|
E:GLY538
|
4.5
|
123.4
|
1.0
|
|
HG2
|
E:GLN537
|
4.6
|
121.3
|
1.0
|
|
C
|
E:PRO284
|
4.7
|
119.0
|
1.0
|
|
HZ3
|
E:LYS288
|
4.7
|
103.1
|
1.0
|
|
HH12
|
E:ARG443
|
4.7
|
130.5
|
1.0
|
|
H
|
E:GLY538
|
4.8
|
123.4
|
1.0
|
|
O2B
|
E:ADP704
|
4.8
|
115.4
|
1.0
|
|
HG3
|
E:GLN537
|
4.8
|
121.3
|
1.0
|
|
HH11
|
E:ARG567
|
4.8
|
133.8
|
1.0
|
|
O1B
|
E:ADP704
|
4.9
|
115.4
|
1.0
|
|
Fluorine binding site 3 out
of 6 in 7rdx
Go back to
Fluorine Binding Sites List in 7rdx
Fluorine binding site 3 out
of 6 in the Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:F706
b:115.0
occ:1.00
|
F3
|
E:AF3706
|
0.0
|
115.0
|
1.0
|
|
AL
|
E:AF3706
|
1.8
|
115.0
|
1.0
|
|
MG
|
E:MG705
|
2.0
|
108.5
|
1.0
|
|
OE2
|
E:GLU375
|
2.1
|
96.7
|
1.0
|
|
OG
|
E:SER289
|
2.6
|
104.9
|
1.0
|
|
F1
|
E:AF3706
|
3.1
|
115.0
|
1.0
|
|
F2
|
E:AF3706
|
3.1
|
115.0
|
1.0
|
|
HE2
|
E:LYS288
|
3.3
|
103.1
|
1.0
|
|
CD
|
E:GLU375
|
3.3
|
96.7
|
1.0
|
|
O3B
|
E:ADP704
|
3.4
|
115.4
|
1.0
|
|
O2B
|
E:ADP704
|
3.6
|
115.4
|
1.0
|
|
HA2
|
E:GLY538
|
3.7
|
123.4
|
1.0
|
|
HG2
|
E:GLU375
|
3.8
|
96.7
|
1.0
|
|
HB2
|
E:LYS288
|
3.8
|
103.1
|
1.0
|
|
HE3
|
E:LYS288
|
3.9
|
103.1
|
1.0
|
|
CE
|
E:LYS288
|
4.0
|
103.1
|
1.0
|
|
CG
|
E:GLU375
|
4.0
|
96.7
|
1.0
|
|
H
|
E:SER289
|
4.1
|
104.9
|
1.0
|
|
PB
|
E:ADP704
|
4.1
|
115.4
|
1.0
|
|
CB
|
E:SER289
|
4.1
|
104.9
|
1.0
|
|
OD1
|
E:ASP374
|
4.2
|
91.4
|
1.0
|
|
HG3
|
E:GLU375
|
4.2
|
96.7
|
1.0
|
|
OE1
|
E:GLU375
|
4.3
|
96.7
|
1.0
|
|
HB3
|
E:SER289
|
4.5
|
104.9
|
1.0
|
|
HZ1
|
E:LYS288
|
4.5
|
103.1
|
1.0
|
|
O1A
|
E:ADP704
|
4.5
|
115.4
|
1.0
|
|
HB2
|
E:SER289
|
4.5
|
104.9
|
1.0
|
|
N
|
E:SER289
|
4.5
|
104.9
|
1.0
|
|
CA
|
E:GLY538
|
4.6
|
123.4
|
1.0
|
|
HE22
|
E:GLN404
|
4.7
|
113.5
|
1.0
|
|
CA
|
E:SER289
|
4.8
|
104.9
|
1.0
|
|
CB
|
E:LYS288
|
4.8
|
103.1
|
1.0
|
|
OD2
|
E:ASP374
|
4.8
|
91.4
|
1.0
|
|
HA
|
E:SER289
|
4.8
|
104.9
|
1.0
|
|
NZ
|
E:LYS288
|
4.9
|
103.1
|
1.0
|
|
HA3
|
E:GLY538
|
4.9
|
123.4
|
1.0
|
|
CG
|
E:ASP374
|
5.0
|
91.4
|
1.0
|
|
Fluorine binding site 4 out
of 6 in 7rdx
Go back to
Fluorine Binding Sites List in 7rdx
Fluorine binding site 4 out
of 6 in the Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:F1005
b:178.2
occ:1.00
|
F1
|
F:AF31005
|
0.0
|
178.2
|
1.0
|
|
AL
|
F:AF31005
|
1.8
|
178.2
|
1.0
|
|
H
|
F:GLY285
|
2.0
|
175.0
|
1.0
|
|
O3B
|
F:ADP1003
|
2.2
|
177.4
|
1.0
|
|
N
|
F:GLY285
|
2.8
|
175.0
|
1.0
|
|
F3
|
F:AF31005
|
3.1
|
178.2
|
1.0
|
|
F2
|
F:AF31005
|
3.1
|
178.2
|
1.0
|
|
HA
|
F:PRO284
|
3.1
|
175.7
|
1.0
|
|
PB
|
F:ADP1003
|
3.1
|
177.4
|
1.0
|
|
HA2
|
F:GLY285
|
3.2
|
175.0
|
1.0
|
|
O1B
|
F:ADP1003
|
3.2
|
177.4
|
1.0
|
|
HH22
|
F:ARG443
|
3.3
|
176.7
|
1.0
|
|
CA
|
F:GLY285
|
3.5
|
175.0
|
1.0
|
|
HH21
|
F:ARG443
|
3.6
|
176.7
|
1.0
|
|
C
|
F:PRO284
|
3.7
|
175.7
|
1.0
|
|
NH2
|
F:ARG443
|
3.8
|
176.7
|
1.0
|
|
CA
|
F:PRO284
|
3.8
|
175.7
|
1.0
|
|
H
|
F:THR286
|
3.8
|
175.6
|
1.0
|
|
HH22
|
F:ARG567
|
3.8
|
175.7
|
1.0
|
|
HZ1
|
F:LYS288
|
3.9
|
173.3
|
1.0
|
|
HB3
|
F:PRO284
|
4.0
|
175.7
|
1.0
|
|
O2B
|
F:ADP1003
|
4.0
|
177.4
|
1.0
|
|
HH21
|
F:ARG567
|
4.1
|
175.7
|
1.0
|
|
HA3
|
F:GLY285
|
4.2
|
175.0
|
1.0
|
|
NH2
|
F:ARG567
|
4.3
|
175.7
|
1.0
|
|
O3A
|
F:ADP1003
|
4.4
|
177.4
|
1.0
|
|
CB
|
F:PRO284
|
4.4
|
175.7
|
1.0
|
|
N
|
F:THR286
|
4.5
|
175.6
|
1.0
|
|
O2A
|
F:ADP1003
|
4.5
|
177.4
|
1.0
|
|
C
|
F:GLY285
|
4.6
|
175.0
|
1.0
|
|
H
|
F:GLY287
|
4.7
|
171.8
|
1.0
|
|
O5'
|
F:ADP1003
|
4.8
|
177.4
|
1.0
|
|
NZ
|
F:LYS288
|
4.8
|
173.3
|
1.0
|
|
HB2
|
F:PRO284
|
4.9
|
175.7
|
1.0
|
|
O
|
F:PRO284
|
4.9
|
175.7
|
1.0
|
|
PA
|
F:ADP1003
|
4.9
|
177.4
|
1.0
|
|
HE2
|
F:LYS288
|
4.9
|
173.3
|
1.0
|
|
O
|
F:PRO283
|
4.9
|
175.8
|
1.0
|
|
Fluorine binding site 5 out
of 6 in 7rdx
Go back to
Fluorine Binding Sites List in 7rdx
Fluorine binding site 5 out
of 6 in the Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:F1005
b:178.2
occ:1.00
|
F2
|
F:AF31005
|
0.0
|
178.2
|
1.0
|
|
H
|
F:THR286
|
1.7
|
175.6
|
1.0
|
|
AL
|
F:AF31005
|
1.8
|
178.2
|
1.0
|
|
HZ1
|
F:LYS288
|
2.0
|
173.3
|
1.0
|
|
N
|
F:THR286
|
2.5
|
175.6
|
1.0
|
|
OG1
|
F:THR286
|
2.5
|
175.6
|
1.0
|
|
H
|
F:GLY285
|
2.6
|
175.0
|
1.0
|
|
HZ3
|
F:LYS288
|
2.6
|
173.3
|
1.0
|
|
O1B
|
F:ADP1003
|
2.6
|
177.4
|
1.0
|
|
H
|
F:GLY287
|
2.6
|
171.8
|
1.0
|
|
NZ
|
F:LYS288
|
2.7
|
173.3
|
1.0
|
|
N
|
F:GLY285
|
3.0
|
175.0
|
1.0
|
|
O2B
|
F:ADP1003
|
3.1
|
177.4
|
1.0
|
|
HG1
|
F:THR286
|
3.1
|
175.6
|
1.0
|
|
F3
|
F:AF31005
|
3.1
|
178.2
|
1.0
|
|
PB
|
F:ADP1003
|
3.1
|
177.4
|
1.0
|
|
F1
|
F:AF31005
|
3.1
|
178.2
|
1.0
|
|
O
|
F:PRO283
|
3.1
|
175.8
|
1.0
|
|
HZ2
|
F:LYS288
|
3.3
|
173.3
|
1.0
|
|
CA
|
F:THR286
|
3.3
|
175.6
|
1.0
|
|
N
|
F:GLY287
|
3.3
|
171.8
|
1.0
|
|
HE2
|
F:LYS288
|
3.4
|
173.3
|
1.0
|
|
C
|
F:GLY285
|
3.4
|
175.0
|
1.0
|
|
CB
|
F:THR286
|
3.4
|
175.6
|
1.0
|
|
HA
|
F:PRO284
|
3.5
|
175.7
|
1.0
|
|
CA
|
F:GLY285
|
3.5
|
175.0
|
1.0
|
|
HG3
|
F:LYS288
|
3.5
|
173.3
|
1.0
|
|
HA2
|
F:GLY285
|
3.6
|
175.0
|
1.0
|
|
CE
|
F:LYS288
|
3.6
|
173.3
|
1.0
|
|
O3B
|
F:ADP1003
|
3.6
|
177.4
|
1.0
|
|
C
|
F:PRO284
|
3.8
|
175.7
|
1.0
|
|
H
|
F:LYS288
|
3.8
|
173.3
|
1.0
|
|
HG23
|
F:THR286
|
3.8
|
175.6
|
1.0
|
|
C
|
F:THR286
|
3.8
|
175.6
|
1.0
|
|
CA
|
F:PRO284
|
4.1
|
175.7
|
1.0
|
|
CG2
|
F:THR286
|
4.1
|
175.6
|
1.0
|
|
C
|
F:PRO283
|
4.2
|
175.8
|
1.0
|
|
HA
|
F:THR286
|
4.2
|
175.6
|
1.0
|
|
HB
|
F:THR286
|
4.2
|
175.6
|
1.0
|
|
HE3
|
F:LYS288
|
4.3
|
173.3
|
1.0
|
|
HG21
|
F:THR286
|
4.3
|
175.6
|
1.0
|
|
CG
|
F:LYS288
|
4.4
|
173.3
|
1.0
|
|
HA3
|
F:GLY285
|
4.5
|
175.0
|
1.0
|
|
N
|
F:LYS288
|
4.5
|
173.3
|
1.0
|
|
CA
|
F:GLY287
|
4.5
|
171.8
|
1.0
|
|
O
|
F:GLY285
|
4.6
|
175.0
|
1.0
|
|
H5'2
|
F:ADP1003
|
4.6
|
177.4
|
1.0
|
|
HA2
|
F:GLY287
|
4.6
|
171.8
|
1.0
|
|
N
|
F:PRO284
|
4.6
|
175.7
|
1.0
|
|
CD
|
F:LYS288
|
4.6
|
173.3
|
1.0
|
|
O3A
|
F:ADP1003
|
4.6
|
177.4
|
1.0
|
|
O
|
F:PRO284
|
4.7
|
175.7
|
1.0
|
|
HA3
|
F:GLY282
|
4.7
|
174.9
|
1.0
|
|
O
|
F:GLY282
|
4.8
|
174.9
|
1.0
|
|
C
|
F:GLY282
|
4.9
|
174.9
|
1.0
|
|
HG22
|
F:THR286
|
5.0
|
175.6
|
1.0
|
|
HG2
|
F:LYS288
|
5.0
|
173.3
|
1.0
|
|
Fluorine binding site 6 out
of 6 in 7rdx
Go back to
Fluorine Binding Sites List in 7rdx
Fluorine binding site 6 out
of 6 in the Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc - Open Class within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:F1005
b:178.2
occ:1.00
|
F3
|
F:AF31005
|
0.0
|
178.2
|
1.0
|
|
AL
|
F:AF31005
|
1.8
|
178.2
|
1.0
|
|
HZ1
|
F:LYS288
|
2.0
|
173.3
|
1.0
|
|
NZ
|
F:LYS288
|
2.6
|
173.3
|
1.0
|
|
HA
|
F:PRO284
|
2.7
|
175.7
|
1.0
|
|
HZ2
|
F:LYS288
|
2.7
|
173.3
|
1.0
|
|
HE3
|
F:LYS288
|
2.9
|
173.3
|
1.0
|
|
HE2
|
F:LYS288
|
3.0
|
173.3
|
1.0
|
|
CE
|
F:LYS288
|
3.1
|
173.3
|
1.0
|
|
F2
|
F:AF31005
|
3.1
|
178.2
|
1.0
|
|
F1
|
F:AF31005
|
3.1
|
178.2
|
1.0
|
|
HE21
|
F:GLN404
|
3.2
|
172.5
|
1.0
|
|
HZ3
|
F:LYS288
|
3.4
|
173.3
|
1.0
|
|
H
|
F:GLY285
|
3.6
|
175.0
|
1.0
|
|
CA
|
F:PRO284
|
3.6
|
175.7
|
1.0
|
|
NE2
|
F:GLN404
|
3.8
|
172.5
|
1.0
|
|
O
|
F:GLY282
|
4.0
|
174.9
|
1.0
|
|
O
|
F:PRO283
|
4.0
|
175.8
|
1.0
|
|
HE22
|
F:GLN404
|
4.1
|
172.5
|
1.0
|
|
HG3
|
F:GLN404
|
4.1
|
172.5
|
1.0
|
|
N
|
F:PRO284
|
4.2
|
175.7
|
1.0
|
|
O3B
|
F:ADP1003
|
4.2
|
177.4
|
1.0
|
|
N
|
F:GLY285
|
4.2
|
175.0
|
1.0
|
|
HB3
|
F:PRO284
|
4.3
|
175.7
|
1.0
|
|
C
|
F:PRO283
|
4.3
|
175.8
|
1.0
|
|
HG3
|
F:GLN537
|
4.3
|
171.5
|
1.0
|
|
C
|
F:PRO284
|
4.5
|
175.7
|
1.0
|
|
CB
|
F:PRO284
|
4.5
|
175.7
|
1.0
|
|
O2B
|
F:ADP1003
|
4.5
|
177.4
|
1.0
|
|
CD
|
F:LYS288
|
4.6
|
173.3
|
1.0
|
|
HG3
|
F:PRO284
|
4.6
|
175.7
|
1.0
|
|
HE21
|
F:GLN537
|
4.6
|
171.5
|
1.0
|
|
HB2
|
F:ASP401
|
4.7
|
173.0
|
1.0
|
|
CD
|
F:GLN404
|
4.7
|
172.5
|
1.0
|
|
PB
|
F:ADP1003
|
4.7
|
177.4
|
1.0
|
|
H
|
F:THR286
|
4.7
|
175.6
|
1.0
|
|
OE2
|
F:GLU375
|
4.7
|
171.8
|
1.0
|
|
CG
|
F:GLN404
|
4.8
|
172.5
|
1.0
|
|
HG3
|
F:LYS288
|
4.9
|
173.3
|
1.0
|
|
HD3
|
F:LYS288
|
4.9
|
173.3
|
1.0
|
|
C
|
F:GLY282
|
4.9
|
174.9
|
1.0
|
|
OG1
|
F:THR286
|
5.0
|
175.6
|
1.0
|
|
CG
|
F:PRO284
|
5.0
|
175.7
|
1.0
|
|
O1B
|
F:ADP1003
|
5.0
|
177.4
|
1.0
|
|
Reference:
J.Chen,
Q.Wang,
B.Malone,
E.C.Llewellyn,
K.Maruthi,
E.T.Eng,
J.Perry,
E.A.Campbell,
D.E.Shaw,
S.A.Darst.
Ensemble Cryo-Electron Microscopy Reveals Conformational States of the Sars-Cov-2 Helicase Replication-Transcription Complex Biorxiv 2021.
DOI: 10.1101/2021.11.10.468168
Page generated: Tue Jul 15 23:28:12 2025
|
