Fluorine in PDB 7sse: Crystal Structure of the Wdr Domain of Human DCAF1 in Complex with Cyca-117-70

All present enzymatic activity of Crystal Structure of the Wdr Domain of Human DCAF1 in Complex with Cyca-117-70:
2.7.11.1;

The structure of Crystal Structure of the Wdr Domain of Human DCAF1 in Complex with Cyca-117-70, PDB code: 7sse was solved by S.Kimani, J.Owen, A.Dong, Y.Li, A.Hutchinson, A.Seitova, V.M.Shahani, M.Schapira, C.H.Arrowsmith, A.M.Edwards, L.Halabelian, Structuralgenomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.00 / 1.62
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	48.956, 87.919, 73.878, 90, 98.72, 90
R / Rfree (%)	20.6 / 23.4

The binding sites of Fluorine atom in the Crystal Structure of the Wdr Domain of Human DCAF1 in Complex with Cyca-117-70 (pdb code 7sse). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the Wdr Domain of Human DCAF1 in Complex with Cyca-117-70, PDB code: 7sse:

Fluorine binding site 1 out of 1 in the Crystal Structure of the Wdr Domain of Human DCAF1 in Complex with Cyca-117-70


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of the Wdr Domain of Human DCAF1 in Complex with Cyca-117-70 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1401 b:40.9 occ:1.00 F A:B1I1401 0.0 40.9 1.0 C9 A:B1I1401 1.4 37.4 1.0 C8 A:B1I1401 2.3 35.0 1.0 C10 A:B1I1401 2.3 35.7 1.0 CD2 A:LEU1313 3.0 36.9 1.0 CG A:LEU1313 3.4 36.5 1.0 CD1 A:LEU1313 3.4 37.9 1.0 CG A:ARG1225 3.6 34.1 1.0 C7 A:B1I1401 3.6 36.2 1.0 C5 A:B1I1401 3.6 35.2 1.0 CD1 A:ILE1262 3.7 25.7 1.0 CB A:ARG1225 3.7 30.9 1.0 CD A:ARG1225 3.8 37.1 1.0 C6 A:B1I1401 4.1 35.5 1.0 NE A:ARG1225 4.3 42.2 1.0 CB A:ARG1298 4.4 30.7 1.0 CE1 A:PHE1330 4.5 32.0 1.0 N A:ARG1298 4.8 28.6 1.0 N A:B1I1401 4.8 34.5 1.0 CA A:ARG1298 4.9 28.9 1.0 CB A:LEU1313 4.9 35.7 1.0 CZ A:PHE1330 5.0 31.0 1.0 O A:HOH1542 5.0 27.6 1.0 CZ A:ARG1225 5.0 45.2 1.0

S.Kimani, J.Owen, A.Dong, Y.Li, A.Hutchinson, A.Seitova, V.M.Shahani, M.Schapira, C.H.Arrowsmith, A.M.Edwards, L.Halabelian, Structural Genomics Consortium (Sgc). Crystal Structure of the Wdr Domain of Human DCAF1 in Complex with Cyca-117-70 To Be Published.