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Atomistry » Fluorine » PDB 7vsg-7wgs » 7wcx | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 7vsg-7wgs » 7wcx » |
Fluorine in PDB 7wcx: Crystal Structure of FGFR4(V550M) Kinase Domain with 7VEnzymatic activity of Crystal Structure of FGFR4(V550M) Kinase Domain with 7V
All present enzymatic activity of Crystal Structure of FGFR4(V550M) Kinase Domain with 7V:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of FGFR4(V550M) Kinase Domain with 7V, PDB code: 7wcx
was solved by
X.J.Chen,
Q.M.Lin,
S.Y.Dai,
Y.H.Chen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7wcx:
The structure of Crystal Structure of FGFR4(V550M) Kinase Domain with 7V also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of FGFR4(V550M) Kinase Domain with 7V
(pdb code 7wcx). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of FGFR4(V550M) Kinase Domain with 7V, PDB code: 7wcx: Fluorine binding site 1 out of 1 in 7wcxGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Crystal Structure of FGFR4(V550M) Kinase Domain with 7V
![]() Mono view ![]() Stereo pair view
Reference:
M.Shao,
X.Chen,
F.Yang,
X.Song,
Y.Zhou,
Q.Lin,
Y.Fu,
R.Ortega,
X.Lin,
Z.Tu,
A.V.Patterson,
J.B.Smaill,
Y.Chen,
X.Lu.
Design, Synthesis, and Biological Evaluation of Aminoindazole Derivatives As Highly Selective Covalent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR4. J.Med.Chem. V. 65 5113 2022.
Page generated: Wed Jul 16 01:27:53 2025
ISSN: ISSN 0022-2623 PubMed: 35271262 DOI: 10.1021/ACS.JMEDCHEM.2C00096 |
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