Fluorine »
PDB 7y4g-7yzq »
7yy3 »
Fluorine in PDB 7yy3: Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7
Enzymatic activity of Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7
All present enzymatic activity of Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7:
2.7.7.3;
2.7.7.3;
Protein crystallography data
The structure of Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7, PDB code: 7yy3
was solved by
S.E.Thomas,
A.G.Coyne,
T.L.Blundell,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 57.05 / 1.54 |
| Space group | C 2 2 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 75.931, 125.405, 119.364, 90, 90, 90 |
| R / Rfree (%) | 21 / 23.6 |
Other elements in 7yy3:
The structure of Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7 also contains other interesting chemical elements:
| Magnesium | (Mg) | 3 atoms |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7
(pdb code 7yy3). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7, PDB code: 7yy3:
Jump to Fluorine binding site number: 1; 2; 3;
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7, PDB code: 7yy3:
Jump to Fluorine binding site number: 1; 2; 3;
Fluorine binding site 1 out of 3 in 7yy3
Go back to
Fluorine Binding Sites List in 7yy3
Fluorine binding site 1 out
of 3 in the Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7 within 5.0Å range:
|
Fluorine binding site 2 out of 3 in 7yy3
Go back to
Fluorine Binding Sites List in 7yy3
Fluorine binding site 2 out
of 3 in the Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7 within 5.0Å range:
|
Fluorine binding site 3 out of 3 in 7yy3
Go back to
Fluorine Binding Sites List in 7yy3
Fluorine binding site 3 out
of 3 in the Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Crystal Structure of Mycobacterium Abscessus Phosphopantetheine Adenylyltransferase in Complex with Fragment 7 within 5.0Å range:
|
Reference:
S.E.Thomas,
W.J.Mccarthy,
J.El Bakali,
K.P.Brown,
S.Y.Kim,
M.Blaszczyk,
V.Mendes,
C.Abell,
R.A.Floto,
A.G.Coyne,
T.L.Blundell.
Structural Characterization of Mycobacterium Abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications For Fragment-Based Drug Design. Front Mol Biosci V. 9 80432 2022.
ISSN: ESSN 2296-889X
PubMed: 35712348
DOI: 10.3389/FMOLB.2022.880432
Page generated: Wed Jul 16 02:19:40 2025
ISSN: ESSN 2296-889X
PubMed: 35712348
DOI: 10.3389/FMOLB.2022.880432
Last articles
Fe in 4PK6Fe in 4PK5
Fe in 4PJY
Fe in 4PIZ
Fe in 4PD4
Fe in 4PIY
Fe in 4PH9
Fe in 4PBU
Fe in 4PIX
Fe in 4PGK
