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Atomistry » Fluorine » PDB 8aau-8b96 » 8aqf » |
Fluorine in PDB 8aqf: Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515Enzymatic activity of Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515
All present enzymatic activity of Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515:
3.1.1.23; Protein crystallography data
The structure of Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515, PDB code: 8aqf
was solved by
M.Jiang,
M.Huizenga,
J.Wirt,
J.Paloczi,
A.Amedi,
R.Van Der Berg,
J.Benz,
L.Collin,
H.Deng,
W.Driever,
B.Florea,
U.Grether,
A.Janssen,
L.Heitman,
T.W.Lam,
F.Mohr,
A.Pavlovic,
I.Ruf,
H.Rutjes,
F.Stevens,
D.Van Der Vliet,
T.Van Der Wel,
M.Wittwer,
C.Boeckel,
P.Pacher,
A.Hohmann,
M.Van Der Stelt,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8aqf:
The structure of Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515
(pdb code 8aqf). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515, PDB code: 8aqf: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 8aqfGo back to![]() ![]()
Fluorine binding site 1 out
of 2 in the Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 2 in 8aqfGo back to![]() ![]()
Fluorine binding site 2 out
of 2 in the Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515
![]() Mono view ![]() Stereo pair view
Reference:
M.Jiang,
M.Van Der Stelt.
Discovery of A Peripheral Restricted, Reversible Monoacylglycerol Lipase Inhibitor That Reduces Liver Injury and Chemotherapy-Induced Neuropathy To Be Published.
Page generated: Wed Jul 16 02:42:11 2025
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