Fluorine in PDB 8b9g: Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna

All present enzymatic activity of Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna:
3.6.4.13;

The structure of Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna also contains other interesting chemical elements:

Aluminium

(Al)

1 atom

The binding sites of Fluorine atom in the Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna (pdb code 8b9g). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna, PDB code: 8b9g:
Jump to Fluorine binding site number: 1; 2; 3; 4;

Fluorine binding site 1 out of 4 in the Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:F1202 b:27.1 occ:1.00 F1 A:ALF1202 0.0 27.1 1.0 AL A:ALF1202 1.9 27.1 1.0 OG1 A:THR414 2.4 24.5 1.0 F4 A:ALF1202 2.6 27.1 1.0 F3 A:ALF1202 2.6 27.1 1.0 O2B A:ADP1201 2.8 11.0 1.0 O A:HOH1301 3.0 30.0 1.0 O3B A:ADP1201 3.3 11.0 1.0 CA A:SER723 3.5 24.5 1.0 PB A:ADP1201 3.5 11.0 1.0 CB A:THR414 3.6 24.5 1.0 O A:HOH1302 3.6 19.6 1.0 OG A:SER723 3.7 24.5 1.0 F2 A:ALF1202 3.7 27.1 1.0 O2A A:ADP1201 3.8 11.0 1.0 CB A:SER723 3.9 24.5 1.0 CG2 A:THR414 4.2 24.5 1.0 OD1 A:ASP507 4.2 24.5 1.0 OE2 A:GLU508 4.2 24.5 1.0 O A:SER723 4.2 24.5 1.0 C A:SER723 4.3 24.5 1.0 N A:SER723 4.4 24.5 1.0 O3A A:ADP1201 4.5 11.0 1.0 CD A:GLU508 4.6 24.5 1.0 PA A:ADP1201 4.6 11.0 1.0 N A:THR414 4.7 24.5 1.0 CA A:THR414 4.8 24.5 1.0 O1B A:ADP1201 4.8 11.0 1.0 OE1 A:GLN440 4.8 24.5 1.0 NH2 A:ARG771 4.8 24.5 0.5 CG A:ASP507 4.9 24.5 1.0 O A:HOH1303 5.0 17.6 1.0 OE1 A:GLU508 5.0 24.5 1.0

Fluorine binding site 2 out of 4 in the Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:F1202 b:27.1 occ:1.00 F2 A:ALF1202 0.0 27.1 1.0 AL A:ALF1202 1.9 27.1 1.0 F3 A:ALF1202 2.6 27.1 1.0 F4 A:ALF1202 2.7 27.1 1.0 CE A:LYS413 2.8 24.5 1.0 OD2 A:ASP507 3.2 24.5 1.0 CB A:LYS413 3.3 24.5 1.0 OG1 A:THR414 3.3 24.5 1.0 O2B A:ADP1201 3.5 11.0 1.0 CD A:LYS413 3.6 24.5 1.0 CG A:ASP507 3.7 24.5 1.0 F1 A:ALF1202 3.7 27.1 1.0 NZ A:LYS413 3.8 24.5 1.0 OD1 A:ASP507 3.9 24.5 1.0 O A:HOH1303 3.9 17.6 1.0 N A:THR414 3.9 24.5 1.0 CG A:MET538 4.0 24.5 1.0 CG A:LYS413 4.0 24.5 1.0 CB A:MET538 4.0 24.5 1.0 OE1 A:GLU508 4.2 24.5 1.0 O A:MET538 4.2 24.5 1.0 PB A:ADP1201 4.3 11.0 1.0 O1B A:ADP1201 4.3 11.0 1.0 C A:MET538 4.4 24.5 1.0 SD A:MET538 4.4 24.5 1.0 CA A:LYS413 4.4 24.5 1.0 CB A:THR414 4.5 24.5 1.0 C A:LYS413 4.5 24.5 1.0 CA A:THR414 4.6 24.5 1.0 CD A:GLU508 4.7 24.5 1.0 O3B A:ADP1201 4.7 11.0 1.0 CB A:ASP507 4.7 24.5 1.0 N A:SER539 4.7 24.5 1.0 CA A:SER539 4.9 24.5 1.0 CA A:MET538 4.9 24.5 1.0

Fluorine binding site 3 out of 4 in the Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:F1202 b:27.1 occ:1.00 F3 A:ALF1202 0.0 27.1 1.0 AL A:ALF1202 1.8 27.1 1.0 O3B A:ADP1201 2.4 11.0 1.0 O A:HOH1302 2.5 19.6 1.0 F2 A:ALF1202 2.6 27.1 1.0 F1 A:ALF1202 2.6 27.1 1.0 O2B A:ADP1201 2.7 11.0 1.0 PB A:ADP1201 2.7 11.0 1.0 O A:HOH1303 3.0 17.6 1.0 O1B A:ADP1201 3.2 11.0 1.0 NZ A:LYS413 3.3 24.5 1.0 CE A:LYS413 3.4 24.5 1.0 F4 A:ALF1202 3.6 27.1 1.0 OG1 A:THR414 3.6 24.5 1.0 OE1 A:GLU508 4.1 24.5 1.0 OE2 A:GLU508 4.1 24.5 1.0 O3A A:ADP1201 4.2 11.0 1.0 CD A:GLU508 4.3 24.5 1.0 CB A:LYS413 4.6 24.5 1.0 CD A:LYS413 4.7 24.5 1.0 NH2 A:ARG771 4.8 24.5 0.5 N A:THR414 4.9 24.5 1.0

Fluorine binding site 4 out of 4 in the Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:F1202 b:27.1 occ:1.00 F4 A:ALF1202 0.0 27.1 1.0 OG1 A:THR414 1.6 24.5 1.0 AL A:ALF1202 1.8 27.1 1.0 OD1 A:ASP507 1.9 24.5 1.0 CG A:ASP507 2.5 24.5 1.0 F1 A:ALF1202 2.6 27.1 1.0 F2 A:ALF1202 2.7 27.1 1.0 CB A:THR414 2.7 24.5 1.0 OD2 A:ASP507 2.9 24.5 1.0 CG2 A:THR414 3.0 24.5 1.0 CA A:THR414 3.5 24.5 1.0 O2B A:ADP1201 3.5 11.0 1.0 CB A:ASP507 3.6 24.5 1.0 F3 A:ALF1202 3.6 27.1 1.0 N A:THR414 3.7 24.5 1.0 NE2 A:GLN440 3.8 24.5 1.0 OE1 A:GLN440 4.5 24.5 1.0 CD A:GLN440 4.6 24.5 1.0 OG A:SER723 4.7 24.5 1.0 CA A:ASP507 4.7 24.5 1.0 PB A:ADP1201 4.8 11.0 1.0 C A:LYS413 4.8 24.5 1.0 CD A:GLU508 4.9 24.5 1.0 C A:THR414 4.9 24.5 1.0 CB A:LYS413 4.9 24.5 1.0 O A:HOH1301 5.0 30.0 1.0

P.K.A.Jagtap, J.Hennig. Cryo-Em Structure of Mle in Complex with Adp:ALF4 and U10 Rna To Be Published.