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Atomistry » Fluorine » PDB 8e90-8eyv » 8ekx » |
Fluorine in PDB 8ekx: Structure of Mbp-Mcl-1 in Complex with MIK665Protein crystallography data
The structure of Structure of Mbp-Mcl-1 in Complex with MIK665, PDB code: 8ekx
was solved by
R.A.Judge,
A.S.Judd,
A.J.Souers,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8ekx:
The structure of Structure of Mbp-Mcl-1 in Complex with MIK665 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of Mbp-Mcl-1 in Complex with MIK665
(pdb code 8ekx). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structure of Mbp-Mcl-1 in Complex with MIK665, PDB code: 8ekx: Fluorine binding site 1 out of 1 in 8ekxGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Structure of Mbp-Mcl-1 in Complex with MIK665
![]() Mono view ![]() Stereo pair view
Reference:
J.Yuda,
C.Will,
D.C.Phillips,
L.Abraham,
C.Alvey,
A.Avigdor,
W.Buck,
L.Besenhofer,
E.Boghaert,
D.Cheng,
D.Cojocari,
K.Doyle,
T.M.Hansen,
K.Huang,
E.F.Johnson,
A.S.Judd,
R.A.Judge,
J.C.Kalvass,
A.Kunzer,
L.T.Lam,
R.Li,
R.L.Martin,
A.Mastracchio,
M.Mitten,
A.Petrich,
J.Wang,
J.E.Ward,
H.Zhang,
X.Wang,
J.E.Wolff,
K.M.Bell-Mcguinn,
A.J.Souers.
Selective Mcl-1 Inhibitor Abbv-467 Is Efficacious in Tumor Models But Is Associated with Cardiac Troponin Increases in Patients. Commun Med (Lond) V. 3 154 2023.
Page generated: Wed Jul 16 03:56:06 2025
ISSN: ISSN 2730-664X PubMed: 37880389 DOI: 10.1038/S43856-023-00380-Z |
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