Fluorine in PDB 8fn0: Cryoem Structure of Go-Coupled NTSR1 with A Biased Allosteric Modulator

The binding sites of Fluorine atom in the Cryoem Structure of Go-Coupled NTSR1 with A Biased Allosteric Modulator (pdb code 8fn0). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Cryoem Structure of Go-Coupled NTSR1 with A Biased Allosteric Modulator, PDB code: 8fn0:

Fluorine binding site 1 out of 1 in the Cryoem Structure of Go-Coupled NTSR1 with A Biased Allosteric Modulator


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryoem Structure of Go-Coupled NTSR1 with A Biased Allosteric Modulator within 5.0Å range: probe atom residue distance (Å) B Occ A:F501 b:77.9 occ:1.00 F1 A:SRW501 0.0 77.9 1.0 C24 A:SRW501 1.4 65.3 1.0 C14 A:SRW501 2.3 65.6 1.0 C25 A:SRW501 2.4 63.2 1.0 C26 A:SRW501 2.5 65.3 1.0 N3 A:SRW501 2.6 65.2 1.0 CD2 B:LEU219 3.3 61.4 1.0 NH1 A:ARG167 3.4 58.7 1.0 CD1 A:ILE171 3.5 56.9 1.0 N2 A:SRW501 3.6 71.0 1.0 CD2 B:LEU224 3.7 78.7 1.0 C15 A:SRW501 4.0 68.2 1.0 CD A:ARG167 4.3 63.6 1.0 CG B:LEU219 4.4 61.3 1.0 CD1 B:LEU219 4.4 62.8 1.0 CZ A:ARG167 4.4 64.0 1.0 CG1 A:ILE171 4.6 55.6 1.0 CD1 A:LEU264 4.6 61.5 1.0 C13 A:SRW501 4.7 65.9 1.0 NE A:ARG167 4.8 72.2 1.0 C20 A:SRW501 4.8 74.2 1.0 C16 A:SRW501 4.9 65.6 1.0 CD1 B:LEU224 4.9 82.5 1.0 CG B:LEU224 4.9 81.5 1.0

B.E.Krumm, J.F.Diberto, R.H.J.Olsen, H.J.Kang, S.T.Slocum, S.Zhang, R.T.Strachan, X.P.Huang, L.M.Slosky, A.B.Pinkerton, L.S.Barak, M.G.Caron, T.Kenakin, J.F.Fay, B.L.Roth. Neurotensin Receptor Allosterism Revealed in Complex with A Biased Allosteric Modulator. Biochemistry 2023.
ISSN: ISSN 0006-2960
PubMed: 36917754
DOI: 10.1021/ACS.BIOCHEM.3C00029