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Atomistry » Fluorine » PDB 8fpe-8g4v » 8fvd | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 8fpe-8g4v » 8fvd » |
Fluorine in PDB 8fvd: E Coli. Ctp Synthase in Complex with Df-Dctp (Potassium Malonate + 100 Mm MGCL2)Enzymatic activity of E Coli. Ctp Synthase in Complex with Df-Dctp (Potassium Malonate + 100 Mm MGCL2)
All present enzymatic activity of E Coli. Ctp Synthase in Complex with Df-Dctp (Potassium Malonate + 100 Mm MGCL2):
6.3.4.2; Protein crystallography data
The structure of E Coli. Ctp Synthase in Complex with Df-Dctp (Potassium Malonate + 100 Mm MGCL2), PDB code: 8fvd
was solved by
T.Holyoak,
M.J.Mcleod,
N.Tran,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8fvd:
The structure of E Coli. Ctp Synthase in Complex with Df-Dctp (Potassium Malonate + 100 Mm MGCL2) also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the E Coli. Ctp Synthase in Complex with Df-Dctp (Potassium Malonate + 100 Mm MGCL2)
(pdb code 8fvd). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the E Coli. Ctp Synthase in Complex with Df-Dctp (Potassium Malonate + 100 Mm MGCL2), PDB code: 8fvd: Jump to Fluorine binding site number: 1; 2; 3; 4; Fluorine binding site 1 out of 4 in 8fvdGo back to![]() ![]()
Fluorine binding site 1 out
of 4 in the E Coli. Ctp Synthase in Complex with Df-Dctp (Potassium Malonate + 100 Mm MGCL2)
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 4 in 8fvdGo back to![]() ![]()
Fluorine binding site 2 out
of 4 in the E Coli. Ctp Synthase in Complex with Df-Dctp (Potassium Malonate + 100 Mm MGCL2)
![]() Mono view ![]() Stereo pair view
Fluorine binding site 3 out of 4 in 8fvdGo back to![]() ![]()
Fluorine binding site 3 out
of 4 in the E Coli. Ctp Synthase in Complex with Df-Dctp (Potassium Malonate + 100 Mm MGCL2)
![]() Mono view ![]() Stereo pair view
Fluorine binding site 4 out of 4 in 8fvdGo back to![]() ![]()
Fluorine binding site 4 out
of 4 in the E Coli. Ctp Synthase in Complex with Df-Dctp (Potassium Malonate + 100 Mm MGCL2)
![]() Mono view ![]() Stereo pair view
Reference:
M.J.Mcleod,
N.Tran,
G.D.Mccluskey,
T.D.Gillis,
S.L.Bearne,
T.Holyoak.
A Metal Dependent Conformational Change Provides A Structural Basis For the Inhibition of Ctp Synthase By Gemcitabine-5'-Triphosphate. Protein Sci. E4648 2023.
Page generated: Wed Jul 16 04:46:30 2025
ISSN: ESSN 1469-896X PubMed: 37106216 DOI: 10.1002/PRO.4648 |
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