Fluorine »
PDB 8ox6-8pb2 »
8p2r »
Fluorine in PDB 8p2r: Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure (3-({[2-(Carboxymethoxy)-4- Fluorobenzoyl]Amino}Methyl)Benzoic Acid)
Enzymatic activity of Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure (3-({[2-(Carboxymethoxy)-4- Fluorobenzoyl]Amino}Methyl)Benzoic Acid)
All present enzymatic activity of Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure (3-({[2-(Carboxymethoxy)-4- Fluorobenzoyl]Amino}Methyl)Benzoic Acid):
1.1.1.21; 1.1.1.300; 1.1.1.372; 1.1.1.54;
1.1.1.21; 1.1.1.300; 1.1.1.372; 1.1.1.54;
Protein crystallography data
The structure of Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure (3-({[2-(Carboxymethoxy)-4- Fluorobenzoyl]Amino}Methyl)Benzoic Acid), PDB code: 8p2r
was solved by
L.-S.Klee,
A.Heine,
G.Klebe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 21.63 / 1.25 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 47.335, 66.813, 49.298, 90, 92.1, 90 |
| R / Rfree (%) | 10.7 / 13.6 |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure (3-({[2-(Carboxymethoxy)-4- Fluorobenzoyl]Amino}Methyl)Benzoic Acid)
(pdb code 8p2r). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure (3-({[2-(Carboxymethoxy)-4- Fluorobenzoyl]Amino}Methyl)Benzoic Acid), PDB code: 8p2r:
Jump to Fluorine binding site number: 1; 2;
In total 2 binding sites of Fluorine where determined in the Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure (3-({[2-(Carboxymethoxy)-4- Fluorobenzoyl]Amino}Methyl)Benzoic Acid), PDB code: 8p2r:
Jump to Fluorine binding site number: 1; 2;
Fluorine binding site 1 out of 2 in 8p2r
Go back to
Fluorine Binding Sites List in 8p2r
Fluorine binding site 1 out
of 2 in the Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure (3-({[2-(Carboxymethoxy)-4- Fluorobenzoyl]Amino}Methyl)Benzoic Acid)
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure (3-({[2-(Carboxymethoxy)-4- Fluorobenzoyl]Amino}Methyl)Benzoic Acid) within 5.0Å range:
|
Fluorine binding site 2 out of 2 in 8p2r
Go back to
Fluorine Binding Sites List in 8p2r
Fluorine binding site 2 out
of 2 in the Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure (3-({[2-(Carboxymethoxy)-4- Fluorobenzoyl]Amino}Methyl)Benzoic Acid)
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure (3-({[2-(Carboxymethoxy)-4- Fluorobenzoyl]Amino}Methyl)Benzoic Acid) within 5.0Å range:
|
Reference:
L.-S.Klee,
A.Heine,
G.Klebe,
F.Scheer.
Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure (3-({[2-(Carboxymethoxy)-4-Fluorobenzoyl]Amino}Methyl) Benzoic Acid) To Be Published.
Page generated: Wed Jul 16 06:18:30 2025
Last articles
Mg in 2WVMMg in 2WVL
Mg in 2WVJ
Mg in 2WVG
Mg in 2WVA
Mg in 2WTZ
Mg in 2WTY
Mg in 2WTP
Mg in 2WTO
Mg in 2WSS
