Fluorine in PDB 8x0d: Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 2

The binding sites of Fluorine atom in the Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 2 (pdb code 8x0d). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 2, PDB code: 8x0d:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:80.7 occ:1.00 F1 A:XQT903 0.0 80.7 1.0 C15 A:XQT903 1.4 78.1 1.0 C16 A:XQT903 2.3 76.7 1.0 C14 A:XQT903 2.3 76.5 1.0 OG A:SER658 2.5 97.0 1.0 O A:SER654 2.5 84.9 1.0 O A:GLY624 2.8 105.2 1.0 C A:GLY624 2.9 105.7 1.0 C A:SER654 3.0 85.2 1.0 CB A:SER658 3.3 97.1 1.0 CA A:GLY624 3.4 108.6 1.0 CB A:SER654 3.5 86.6 1.0 C17 A:XQT903 3.6 75.6 1.0 N A:ILE625 3.6 103.8 1.0 CA A:SER654 3.6 86.8 1.0 C13 A:XQT903 3.6 74.6 1.0 N A:PRO655 3.7 87.0 1.0 CA A:ILE625 4.1 105.3 1.0 C18 A:XQT903 4.1 75.3 1.0 CA A:PRO655 4.1 90.8 1.0 N A:SER658 4.2 98.9 1.0 CA A:SER658 4.4 96.8 1.0 OG A:SER654 4.7 86.8 1.0 N A:GLY624 4.8 109.0 1.0 C12 A:XQT903 4.8 71.8 1.0 C A:PRO655 4.8 95.7 1.0 CD A:PRO655 4.8 88.5 1.0 N A:GLY628 4.8 93.3 1.0 CA A:GLY628 4.9 91.0 1.0 CG1 A:ILE625 4.9 109.6 1.0

Fluorine binding site 2 out of 2 in the Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 2 within 5.0Å range: probe atom residue distance (Å) B Occ B:F903 b:92.0 occ:1.00 F1 B:XQT903 0.0 92.0 1.0 C15 B:XQT903 1.4 89.8 1.0 C16 B:XQT903 2.3 90.2 1.0 C14 B:XQT903 2.4 89.2 1.0 O B:GLY624 2.6 109.5 1.0 OG B:SER658 2.8 103.3 1.0 C B:GLY624 2.9 108.7 1.0 CB B:SER654 3.2 99.8 1.0 O B:SER654 3.2 101.9 1.0 C B:SER654 3.3 101.1 1.0 N B:ILE625 3.5 103.2 1.0 C17 B:XQT903 3.6 88.8 1.0 C13 B:XQT903 3.6 89.2 1.0 CA B:SER654 3.7 101.3 1.0 CA B:GLY624 3.7 112.0 1.0 CA B:ILE625 3.8 99.3 1.0 CB B:SER658 3.8 104.3 1.0 N B:PRO655 3.9 100.8 1.0 OG B:SER654 4.1 98.5 1.0 C18 B:XQT903 4.1 88.6 1.0 CA B:GLY628 4.2 89.0 1.0 N B:GLY628 4.4 92.2 1.0 CA B:PRO655 4.4 102.2 1.0 C B:ILE625 4.6 100.5 1.0 CG1 B:ILE625 4.8 97.9 1.0 O B:ILE625 4.8 100.3 1.0 C12 B:XQT903 4.8 89.4 1.0 CD B:PRO655 4.8 101.3 1.0 CB B:ILE625 4.9 97.8 1.0 N B:SER658 5.0 106.0 1.0 CA B:SER658 5.0 103.3 1.0

K.R.Vinothkumar, G.Lebon, G.Cannone. Conformational Diversity in Class C Gpcr Positive Allosteric Modulation To Be Published.