Fluorine in PDB 8zyu: Cryo-Em Structure of Neurotensin Receptor 1 in Complex with Beta- ARRESTIN1 and Sbi-553 (Complex 1)

The binding sites of Fluorine atom in the Cryo-Em Structure of Neurotensin Receptor 1 in Complex with Beta- ARRESTIN1 and Sbi-553 (Complex 1) (pdb code 8zyu). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Cryo-Em Structure of Neurotensin Receptor 1 in Complex with Beta- ARRESTIN1 and Sbi-553 (Complex 1), PDB code: 8zyu:

Fluorine binding site 1 out of 1 in the Cryo-Em Structure of Neurotensin Receptor 1 in Complex with Beta- ARRESTIN1 and Sbi-553 (Complex 1)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryo-Em Structure of Neurotensin Receptor 1 in Complex with Beta- ARRESTIN1 and Sbi-553 (Complex 1) within 5.0Å range: probe atom residue distance (Å) B Occ R:F500 b:27.5 occ:1.00 F1 R:SRW500 0.0 27.5 1.0 C24 R:SRW500 1.4 20.6 1.0 C25 R:SRW500 2.4 22.4 1.0 C26 R:SRW500 2.4 27.4 1.0 C14 R:SRW500 2.4 24.5 1.0 N3 R:SRW500 2.7 26.5 1.0 NH1 R:ARG166 2.7 31.3 1.0 CD1 R:ILE170 3.5 39.3 1.0 N2 R:SRW500 3.6 29.7 1.0 CD2 R:LEU298 3.9 33.2 1.0 CZ R:ARG166 3.9 35.1 1.0 CD R:ARG166 4.0 34.6 1.0 C15 R:SRW500 4.0 18.2 1.0 CE2 R:PHE286 4.3 43.2 1.0 CG1 R:ILE170 4.4 40.8 1.0 NE R:ARG166 4.4 35.2 1.0 CD2 R:PHE286 4.5 41.6 1.0 C13 R:SRW500 4.7 25.4 1.0 CB R:ARG166 4.9 29.2 1.0 C20 R:SRW500 4.9 18.5 1.0 C16 R:SRW500 4.9 22.0 1.0 CG R:ARG166 5.0 28.4 1.0 NH2 R:ARG166 5.0 31.3 1.0

D.Sun, X.Li, Q.Yuan, Y.Wang, P.Shi, H.Zhang, T.Wang, W.Sun, S.Ling, Y.Liu, J.Lai, W.Xie, W.Yin, L.Liu, H.E.Xu, C.Tian. Molecular Mechanism of the Arrestin-Biased Agonism of Neurotensin Receptor 1 By An Intracellular Allosteric Modulator. Cell Res. V. 35 284 2025.
ISSN: ISSN 1001-0602
PubMed: 40118988
DOI: 10.1038/S41422-025-01095-7