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Atomistry » Fluorine » PDB 1dvz-1fk9 » 1eet » |
Fluorine in PDB 1eet: Hiv-1 Reverse Transcriptase in Complex with the Inhibitor MSC204Enzymatic activity of Hiv-1 Reverse Transcriptase in Complex with the Inhibitor MSC204
All present enzymatic activity of Hiv-1 Reverse Transcriptase in Complex with the Inhibitor MSC204:
2.7.7.49; Protein crystallography data
The structure of Hiv-1 Reverse Transcriptase in Complex with the Inhibitor MSC204, PDB code: 1eet
was solved by
M.Hogberg,
C.Sahlberg,
P.Engelhardt,
R.Noreen,
J.Kangasmetsa,
N.G.Johansson,
B.Oberg,
L.Vrang,
H.Zhang,
B.L.Sahlberg,
T.Unge,
S.Lovgren,
K.Fridborg,
K.Backbro,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1eet:
The structure of Hiv-1 Reverse Transcriptase in Complex with the Inhibitor MSC204 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Hiv-1 Reverse Transcriptase in Complex with the Inhibitor MSC204
(pdb code 1eet). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Hiv-1 Reverse Transcriptase in Complex with the Inhibitor MSC204, PDB code: 1eet: Fluorine binding site 1 out of 1 in 1eetGo back to Fluorine Binding Sites List in 1eet
Fluorine binding site 1 out
of 1 in the Hiv-1 Reverse Transcriptase in Complex with the Inhibitor MSC204
Mono view Stereo pair view
Reference:
M.Hogberg,
C.Sahlberg,
P.Engelhardt,
R.Noreen,
J.Kangasmetsa,
N.G.Johansson,
B.Oberg,
L.Vrang,
H.Zhang,
B.L.Sahlberg,
T.Unge,
S.Lovgren,
K.Fridborg,
K.Backbro.
Urea-Pett Compounds As A New Class of Hiv-1 Reverse Transcriptase Inhibitors. 3. Synthesis and Further Structure-Activity Relationship Studies of Pett Analogues. J.Med.Chem. V. 42 4150 1999.
Page generated: Sun Dec 13 11:29:16 2020
ISSN: ISSN 0022-2623 PubMed: 10514285 DOI: 10.1021/JM990572Y |
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