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Atomistry » Fluorine » PDB 1h2j-1j97 » 1hfs » |
Fluorine in PDB 1hfs: Crystal Structure of the Catalytic Domain of Human Fibroblast Stromelysin-1 Inhibited with the N-Carboxy-Alkyl Inhibitor L-764,004Enzymatic activity of Crystal Structure of the Catalytic Domain of Human Fibroblast Stromelysin-1 Inhibited with the N-Carboxy-Alkyl Inhibitor L-764,004
All present enzymatic activity of Crystal Structure of the Catalytic Domain of Human Fibroblast Stromelysin-1 Inhibited with the N-Carboxy-Alkyl Inhibitor L-764,004:
3.4.24.17; Protein crystallography data
The structure of Crystal Structure of the Catalytic Domain of Human Fibroblast Stromelysin-1 Inhibited with the N-Carboxy-Alkyl Inhibitor L-764,004, PDB code: 1hfs
was solved by
J.W.Becker,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1hfs:
The structure of Crystal Structure of the Catalytic Domain of Human Fibroblast Stromelysin-1 Inhibited with the N-Carboxy-Alkyl Inhibitor L-764,004 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the Catalytic Domain of Human Fibroblast Stromelysin-1 Inhibited with the N-Carboxy-Alkyl Inhibitor L-764,004
(pdb code 1hfs). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the Catalytic Domain of Human Fibroblast Stromelysin-1 Inhibited with the N-Carboxy-Alkyl Inhibitor L-764,004, PDB code: 1hfs: Fluorine binding site 1 out of 1 in 1hfsGo back to Fluorine Binding Sites List in 1hfs
Fluorine binding site 1 out
of 1 in the Crystal Structure of the Catalytic Domain of Human Fibroblast Stromelysin-1 Inhibited with the N-Carboxy-Alkyl Inhibitor L-764,004
Mono view Stereo pair view
Reference:
C.K.Esser,
R.L.Bugianesi,
C.G.Caldwell,
K.T.Chapman,
P.L.Durette,
N.N.Girotra,
I.E.Kopka,
T.J.Lanza,
D.A.Levorse,
M.Maccoss,
K.A.Owens,
M.M.Ponpipom,
J.P.Simeone,
R.K.Harrison,
L.Niedzwiecki,
J.W.Becker,
A.I.Marcy,
M.G.Axel,
A.J.Christen,
J.Mcdonnell,
V.L.Moore,
J.M.Olszewski,
C.Saphos,
D.M.Visco,
F.Shen,
A.Colletti,
P.A.Krieter,
W.K.Hagmann.
Inhibition of Stromelysin-1 (Mmp-3) By P1'-Biphenylylethyl Carboxyalkyl Dipeptides. J.Med.Chem. V. 40 1026 1997.
Page generated: Sun Dec 13 11:30:06 2020
ISSN: ISSN 0022-2623 PubMed: 9083493 DOI: 10.1021/JM960465T |
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